Differential Expression Analysis on cis-Genes

library(dplyr)
library(ggplot2)
library(knitr)
library(kableExtra)
library(gridExtra)
options(stringsAsFactors = F)
dir = '/project2/xinhe/CROP_seq/line_09_11/'

Cell Filtering

We first visualize some QC metrics of Glut-09,11 single-cell RNA-seq raw count data, and use these to filter outlier cells:

include_graphics(paste0(dir,'filtered_feature_bc_matrix/seurat_cell_stats.png'))

We only keep cells with number of unique genes detected (nFeature_RNA) > 3000 and percentage of mitochondria counts (percent.mt) < 15%; then we further filter out cells that have no MAP2 reads detected. In the end, 8921 MAP2+ cells were kept.

gRNA Conditions for Differential Expression Analysis

After we further removed cells that don’t have any designed gRNAs detected, there are 8015 cells left. We partition these cells for DE analysis in this way:

For each designed gRNA (21x3 in total) condition, we partition all of the cells into 2 groups: cells that contain that gRNA, and cells that do not contain that gRNA.

Number of target cells per gRNA condition:

	gRNA 1	gRNA 2	gRNA 3
BAG5	221	316	122
BCL11B	129	343	148
CHRNA3	77	134	100
DPYD	263	509	228
GALNT10	299	224	368
KCTD13	213	126	71
KMT2E	50	172	175
LINC00637	284	241	348
LOC100507431	99	153	321
LOC105376975	215	401	130
miR137	304	228	358
NAB2	231	161	162
NGEF	79	31	54
PBRM1	77	85	76
PCDHA123	298	441	536
PPP1R16B	316	265	236
RERE	437	246	196
STAT6	205	280	246
TRANK1	9	122	485
UBE2Q2P1	80	79	116
VPS45	96	488	97

We excluded gRNA conditions that result in < 50 target cells, ‘NGEF_2’ and ‘TRANK1_1’, from the subsequent sctransform analysis.

sctranform + t test

We used sctransform to convert the raw UMI count matrix of the 8921 cells into ‘Pearson residuals’ using the following command:

sctransform::vst(sparse_counts,n_genes = NULL,return_gene_attr = TRUE, return_cell_attr = TRUE)

And then used Student’s t test on the sctransformed expression data to test for differentially expressed genes in test and control groups of cells.

We only tested for genes that were expressed in > 20% of all 8921 cells.

In cis analysis, we only need to focus on genes within \(\pm\) 500kb / 1MB of the gRNA locus of interest. Then for each gRNA condition, we test for differential expression in target vs non-target cells for each of the cis genes using categorical regression (Student’s t test).

For DE analysis on each gRNA, to ensure there is no inflation of p value, we performed permutation 20 times by scrambling the labels of all cells and conducting t test on all genes (10260 with > 20% detection rate). Then, we used all 10260 \(\times\) 20 t statistics obtained as the null distribution to compute the empirical p value of each gene.

The null p value distribution of 936 1Mb cis-gene - gRNA pairs over 20 permutations is shown here:

We can see that our DE method of sctransform followed by t test does not result in inflation of small p values.

500 kb cis gene result

cis_summary = readRDS(paste0(dir,'cis_analysis/result/cis_summary_gRNA.MAP2_8921_cells_detailed.rds'))
formatted.df = cis_summary$cis_summary_500kb
fdr_num = dim(filter(formatted.df, pval_adj_cis < 0.1))[1]
pval_num = dim(filter(formatted.df, empirical_pval < 0.05))[1]
formatted.df = select(formatted.df, c('SNP','locus','gRNA','gene','beta','pval',
                                        'empirical_pval','pval_adj_cis')) %>% arrange(pval_adj_cis)
formatted.df[,5:8] = signif(formatted.df[,5:8], digits = 3)
mutate(formatted.df, 
       beta = cell_spec(beta, "html", color = ifelse(beta < 0, "red", "blue")),
       pval = cell_spec(pval, "html", color = ifelse(pval < 0.05, "orange", "black")),
       pval_adj_cis = cell_spec(pval_adj_cis, "html", color = ifelse(pval_adj_cis < 0.1, "red", "black")),
       empirical_pval = cell_spec(empirical_pval, "html", color = ifelse(empirical_pval < 0.05, "orange", "black"))) %>% 
  kable(format = "html", escape = F) %>%
  kable_styling() %>% scroll_box(width = "100%", height = "400px")

SNP	locus	gRNA	gene	beta	pval	empirical_pval	pval_adj_cis
rs2027349	VPS45	VPS45_2_gene	VPS45	-0.448	3.68e-25	2.44e-06	0.00123
rs2027349	VPS45	VPS45_3_gene	VPS45	-0.505	1.04e-07	1.46e-05	0.0037
rs7148456	BAG5	BAG5_2_gene	BAG5	-0.233	7.28e-05	0.000239	0.0302
rs10933	PBRM1	PBRM1_3_gene	PBRM1	-0.502	5.55e-05	0.000185	0.0302
rs10933	PBRM1	PBRM1_3_gene	GNL3	-0.443	0.000143	0.000351	0.0355
rs10933	PBRM1	PBRM1_2_gene	PBRM1	-0.385	0.00108	0.00131	0.11
rs4151680	PCDHA123	PCDHA123_2_gene	HARS2	-0.121	0.00528	0.00481	0.203
rs4151680	PCDHA123	PCDHA123_3_gene	WDR55	0.118	0.00295	0.00317	0.203
rs324015	STAT6	STAT6_2_gene	R3HDM2	-0.191	0.00304	0.00383	0.203
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	SEC11A	0.237	0.0059	0.00473	0.203
rs2027349	VPS45	VPS45_1_gene	VPS45	-0.274	0.00411	0.00474	0.203
rs2027349	VPS45	VPS45_2_gene	ECM1	0.463	0.00532	0.00433	0.203
rs2027349	VPS45	VPS45_3_gene	ANP32E	0.711	0.00402	0.00534	0.208
rs12716973	KCTD13	KCTD13_2_gene	TMEM219	0.215	0.00719	0.00872	0.265
rs4151680	PCDHA123	PCDHA123_2_gene	HBEGF	0.516	0.00901	0.00834	0.265
rs324015	STAT6	STAT6_2_gene	PTGES3	-0.153	0.0075	0.00891	0.265
rs2027349	VPS45	VPS45_2_gene	APH1A	0.123	0.0101	0.00851	0.265
rs3861678	LINC00637	LINC00637_2_gene	CKB	-0.344	0.0117	0.0105	0.294
rs12716973	KCTD13	KCTD13_3_gene	ALDOA	0.265	0.00998	0.0111	0.296
rs12716973	KCTD13	KCTD13_2_gene	KCTD13	-0.25	0.0119	0.0138	0.304
rs4151680	PCDHA123	PCDHA123_2_gene	WDR55	-0.106	0.0144	0.0133	0.304
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA12	0.139	0.0128	0.0124	0.304
rs2027349	VPS45	VPS45_3_gene	HIST2H2BE	-0.314	0.0103	0.0127	0.304
rs2027349	VPS45	VPS45_2_gene	C1orf54	0.267	0.0173	0.0147	0.309
rs10933	PBRM1	PBRM1_2_gene	SFMBT1	-0.25	0.0164	0.0157	0.318
rs324017	NAB2	NAB2_1_gene	NACA	-0.109	0.0191	0.0168	0.326
rs12895055	BCL11B	BCL11B_1_gene	CCNK	-0.198	0.0175	0.0193	0.361
rs10933	PBRM1	PBRM1_1_gene	NT5DC2	0.312	0.0209	0.02	0.361
rs12716973	KCTD13	KCTD13_3_gene	HIRIP3	0.313	0.0203	0.0208	0.363
rs12895055	BCL11B	BCL11B_3_gene	SETD3	0.168	0.023	0.0248	0.404
rs4151680	PCDHA123	PCDHA123_2_gene	SLC35A4	-0.0944	0.0263	0.0246	0.404
rs12716973	KCTD13	KCTD13_2_gene	MAPK3	-0.206	0.0251	0.027	0.426
rs324017	NAB2	NAB2_2_gene	MBD6	-0.161	0.0296	0.0292	0.448
rs7148456	BAG5	BAG5_3_gene	TRMT61A	-0.183	0.0253	0.031	0.462
rs2192932	KMT2E	KMT2E_3_gene	SRPK2	-0.175	0.0353	0.0344	0.498
rs2027349	VPS45	VPS45_2_gene	RPRD2	-0.0945	0.0408	0.0359	0.505
rs7148456	BAG5	BAG5_1_gene	APOPT1	-0.121	0.0431	0.0395	0.523
rs7148456	BAG5	BAG5_3_gene	CKB	-0.397	0.0372	0.0444	0.523
rs4151680	PCDHA123	PCDHA123_3_gene	APBB3	0.0968	0.0424	0.0408	0.523
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA10	-0.105	0.0422	0.0406	0.523
rs324015	STAT6	STAT6_1_gene	PRIM1	-0.168	0.044	0.0437	0.523
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	NMB	0.198	0.0501	0.0427	0.523
rs2027349	VPS45	VPS45_2_gene	ANP32E	0.222	0.0493	0.0442	0.523
rs12716973	KCTD13	KCTD13_2_gene	PPP4C	-0.137	0.0504	0.0517	0.587
rs10933	PBRM1	PBRM1_2_gene	TWF2	0.186	0.0543	0.0522	0.587
rs7170068	CHRNA3	CHRNA3_3_gene	CHRNA3	-0.686	0.0572	0.0554	0.609
rs12895055	BCL11B	BCL11B_3_gene	CCNK	-0.149	0.0569	0.059	0.635
rs7148456	BAG5	BAG5_3_gene	BAG5	-0.175	0.0602	0.0691	0.644
rs12716973	KCTD13	KCTD13_2_gene	SEZ6L2	0.342	0.0661	0.0671	0.644
rs3861678	LINC00637	LINC00637_1_gene	PPP1R13B	-0.123	0.0687	0.07	0.644
rs4151680	PCDHA123	PCDHA123_1_gene	NDUFA2	0.0874	0.0732	0.0688	0.644
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB9	0.122	0.0659	0.0625	0.644
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ZNF592	0.193	0.0631	0.0634	0.644
rs2027349	VPS45	VPS45_3_gene	HIST2H2AC	-0.362	0.062	0.067	0.644
rs2027349	VPS45	VPS45_3_gene	SF3B4	0.171	0.063	0.068	0.644
rs7148456	BAG5	BAG5_1_gene	TRMT61A	0.106	0.0847	0.0794	0.645
rs7148456	BAG5	BAG5_2_gene	KLC1	-0.167	0.0644	0.0742	0.645
rs520843	GALNT10	GALNT10_1_gene	FAM114A2	0.0937	0.0846	0.0816	0.645
rs520843	GALNT10	GALNT10_3_gene	MFAP3	0.0889	0.0736	0.0756	0.645
rs3861678	LINC00637	LINC00637_2_gene	MARK3	-0.104	0.0846	0.08	0.645
rs4151680	PCDHA123	PCDHA123_1_gene	APBB3	0.108	0.086	0.0812	0.645
rs4151680	PCDHA123	PCDHA123_1_gene	HARS	0.0964	0.0822	0.0775	0.645
rs324015	STAT6	STAT6_2_gene	PIP4K2C	-0.104	0.071	0.0763	0.645
rs2027349	VPS45	VPS45_3_gene	SV2A	-0.35	0.0712	0.0765	0.645
rs7170068	CHRNA3	CHRNA3_3_gene	IDH3A	-0.201	0.0885	0.0856	0.659
rs4151680	PCDHA123	PCDHA123_3_gene	HARS2	-0.0669	0.0907	0.0866	0.659
rs2027349	VPS45	VPS45_3_gene	CA14	0.452	0.0812	0.0872	0.659
rs12895055	BCL11B	BCL11B_2_gene	CCNK	-0.0891	0.0861	0.0922	0.667
rs12716973	KCTD13	KCTD13_2_gene	PRRT2	-0.218	0.092	0.092	0.667
rs10933	PBRM1	PBRM1_1_gene	GLT8D1	0.168	0.0953	0.0922	0.667
rs7170068	CHRNA3	CHRNA3_2_gene	PSMA4	0.125	0.0931	0.095	0.668
rs9882911	TRANK1	TRANK1_3_gene	EPM2AIP1	-0.0804	0.0965	0.0951	0.668
rs7170068	CHRNA3	CHRNA3_2_gene	CHRNA3	-0.518	0.097	0.099	0.686
rs12716973	KCTD13	KCTD13_1_gene	ALDOA	0.0977	0.103	0.103	0.692
rs12716973	KCTD13	KCTD13_1_gene	ZNF48	0.116	0.101	0.102	0.692
rs12716973	KCTD13	KCTD13_2_gene	ALDOA	0.125	0.106	0.105	0.692
rs10933	PBRM1	PBRM1_3_gene	WDR82	0.172	0.113	0.106	0.692
rs2027349	VPS45	VPS45_3_gene	RPRD2	0.166	0.101	0.107	0.692
rs12716973	KCTD13	KCTD13_3_gene	MVP	-0.257	0.113	0.11	0.705
rs324017	NAB2	NAB2_3_gene	MBD6	0.117	0.111	0.112	0.71
rs10933	PBRM1	PBRM1_1_gene	GNL3	0.179	0.122	0.118	0.715
rs2027349	VPS45	VPS45_1_gene	ANP32E	0.387	0.12	0.118	0.715
rs2027349	VPS45	VPS45_1_gene	BOLA1	-0.145	0.12	0.119	0.715
rs2027349	VPS45	VPS45_3_gene	C1orf54	0.39	0.112	0.119	0.715
rs2192932	KMT2E	KMT2E_3_gene	KMT2E	-0.143	0.128	0.125	0.719
rs324017	NAB2	NAB2_1_gene	SHMT2	0.11	0.132	0.123	0.719
rs4151680	PCDHA123	PCDHA123_3_gene	HBEGF	0.274	0.129	0.124	0.719
rs324015	STAT6	STAT6_3_gene	MARS	0.0926	0.13	0.125	0.719
rs12716973	KCTD13	KCTD13_1_gene	ASPHD1	-0.169	0.128	0.13	0.72
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB5	0.082	0.132	0.127	0.72
rs324015	STAT6	STAT6_2_gene	MBD6	-0.0876	0.121	0.128	0.72
rs12716973	KCTD13	KCTD13_3_gene	PPP4C	0.139	0.136	0.133	0.729
rs12895055	BCL11B	BCL11B_1_gene	SETD3	0.119	0.132	0.138	0.742
rs7170068	CHRNA3	CHRNA3_3_gene	IREB2	-0.136	0.143	0.138	0.742
rs12716973	KCTD13	KCTD13_1_gene	FAM57B	-0.214	0.138	0.139	0.742
rs324017	NAB2	NAB2_1_gene	NXPH4	0.285	0.155	0.144	0.757
rs10933	PBRM1	PBRM1_3_gene	NISCH	-0.161	0.153	0.145	0.757
rs7170068	CHRNA3	CHRNA3_3_gene	MORF4L1	-0.119	0.154	0.149	0.761
rs10933	PBRM1	PBRM1_1_gene	PBRM1	-0.176	0.154	0.15	0.761
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	WDR73	0.155	0.146	0.147	0.761
rs12716973	KCTD13	KCTD13_1_gene	SEPT1	-0.0939	0.154	0.156	0.774
rs12716973	KCTD13	KCTD13_2_gene	MVP	0.172	0.159	0.158	0.774
rs324017	NAB2	NAB2_2_gene	KIF5A	-0.224	0.159	0.159	0.774
rs186132169	NGEF	NGEF_3_gene	EIF4E2	0.181	0.165	0.157	0.774
rs7148456	BAG5	BAG5_2_gene	MARK3	-0.0739	0.162	0.175	0.785
rs520843	GALNT10	GALNT10_3_gene	SAP30L	-0.0649	0.17	0.174	0.785
rs3861678	LINC00637	LINC00637_3_gene	BAG5	-0.076	0.175	0.175	0.785
rs10933	PBRM1	PBRM1_1_gene	WDR82	0.146	0.174	0.169	0.785
rs10933	PBRM1	PBRM1_3_gene	SFMBT1	-0.15	0.172	0.165	0.785
rs301791	RERE	RERE_1_gene	ENO1	0.0859	0.173	0.169	0.785
rs324015	STAT6	STAT6_2_gene	BAZ2A	-0.0829	0.166	0.174	0.785
rs2027349	VPS45	VPS45_1_gene	CA14	0.356	0.173	0.171	0.785
rs2027349	VPS45	VPS45_3_gene	BOLA1	0.13	0.163	0.17	0.785
rs324017	NAB2	NAB2_1_gene	R3HDM2	-0.093	0.188	0.177	0.787
rs3861678	LINC00637	LINC00637_3_gene	ZFYVE21	0.065	0.179	0.179	0.788
rs7170068	CHRNA3	CHRNA3_1_gene	PSMA4	-0.126	0.196	0.183	0.796
rs7170068	CHRNA3	CHRNA3_2_gene	CTSH	0.131	0.185	0.189	0.804
rs12716973	KCTD13	KCTD13_2_gene	TAOK2	0.104	0.19	0.189	0.804
rs301791	RERE	RERE_1_gene	PARK7	0.0465	0.194	0.19	0.804
rs2027349	VPS45	VPS45_3_gene	APH1A	0.139	0.182	0.191	0.804
rs4151680	PCDHA123	PCDHA123_1_gene	ANKHD1	-0.0671	0.201	0.194	0.812
rs3861678	LINC00637	LINC00637_2_gene	TRMT61A	-0.0743	0.206	0.198	0.814
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ZSCAN2	-0.144	0.192	0.197	0.814
rs7148456	BAG5	BAG5_1_gene	BAG5	-0.0788	0.258	0.251	0.821
rs7148456	BAG5	BAG5_2_gene	PPP1R13B	-0.0763	0.235	0.249	0.821
rs7170068	CHRNA3	CHRNA3_1_gene	CHRNA3	-0.451	0.272	0.257	0.821
rs7170068	CHRNA3	CHRNA3_1_gene	IREB2	0.11	0.299	0.284	0.821
rs520843	GALNT10	GALNT10_3_gene	GALNT10	0.0687	0.262	0.268	0.821
rs520843	GALNT10	GALNT10_3_gene	LARP1	0.0543	0.272	0.277	0.821
rs12716973	KCTD13	KCTD13_1_gene	KCTD13	-0.0944	0.219	0.221	0.821
rs12716973	KCTD13	KCTD13_1_gene	PPP4C	0.0598	0.27	0.273	0.821
rs12716973	KCTD13	KCTD13_1_gene	QPRT	0.117	0.271	0.274	0.821
rs12716973	KCTD13	KCTD13_1_gene	YPEL3	-0.1	0.279	0.282	0.821
rs12716973	KCTD13	KCTD13_1_gene	ZNF771	0.0812	0.205	0.206	0.821
rs12716973	KCTD13	KCTD13_2_gene	MAZ	-0.107	0.216	0.215	0.821
rs12716973	KCTD13	KCTD13_3_gene	CD2BP2	0.131	0.218	0.216	0.821
rs12716973	KCTD13	KCTD13_3_gene	MAPK3	0.149	0.221	0.22	0.821
rs12716973	KCTD13	KCTD13_3_gene	SEPT1	-0.122	0.281	0.279	0.821
rs12716973	KCTD13	KCTD13_3_gene	YPEL3	0.184	0.249	0.247	0.821
rs12716973	KCTD13	KCTD13_3_gene	ZNF771	0.126	0.253	0.251	0.821
rs3861678	LINC00637	LINC00637_2_gene	ZFYVE21	0.0679	0.24	0.232	0.821
rs3861678	LINC00637	LINC00637_3_gene	PPP1R13B	-0.0683	0.266	0.265	0.821
rs324017	NAB2	NAB2_1_gene	PRIM1	-0.0946	0.229	0.218	0.821
rs324017	NAB2	NAB2_2_gene	NACA	-0.0667	0.23	0.232	0.821
rs324017	NAB2	NAB2_3_gene	NAB2	-0.0975	0.256	0.258	0.821
rs324017	NAB2	NAB2_3_gene	NACA	-0.0649	0.241	0.243	0.821
rs324017	NAB2	NAB2_3_gene	R3HDM2	0.107	0.203	0.205	0.821
rs186132169	NGEF	NGEF_1_gene	DGKD	-0.141	0.244	0.24	0.821
rs186132169	NGEF	NGEF_1_gene	TIGD1	-0.125	0.274	0.27	0.821
rs186132169	NGEF	NGEF_3_gene	ATG16L1	-0.154	0.24	0.231	0.821
rs186132169	NGEF	NGEF_3_gene	DGKD	-0.157	0.286	0.276	0.821
rs10933	PBRM1	PBRM1_1_gene	BAP1	-0.109	0.271	0.267	0.821
rs10933	PBRM1	PBRM1_2_gene	GNL3	-0.129	0.243	0.242	0.821
rs10933	PBRM1	PBRM1_3_gene	ALAS1	-0.117	0.256	0.248	0.821
rs10933	PBRM1	PBRM1_3_gene	NT5DC2	-0.143	0.292	0.283	0.821
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB10	0.0947	0.261	0.253	0.821
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB5	-0.0754	0.251	0.243	0.821
rs4151680	PCDHA123	PCDHA123_2_gene	SRA1	-0.0507	0.29	0.282	0.821
rs4151680	PCDHA123	PCDHA123_3_gene	NDUFA2	-0.0416	0.26	0.255	0.821
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB14	0.0662	0.222	0.217	0.821
rs6071578	PPP1R16B	PPP1R16B_2_gene	ACTR5	0.0647	0.281	0.279	0.821
rs6071578	PPP1R16B	PPP1R16B_2_gene	RALGAPB	0.0645	0.276	0.273	0.821
rs301791	RERE	RERE_3_gene	RERE	-0.0938	0.244	0.248	0.821
rs324015	STAT6	STAT6_2_gene	DCTN2	-0.0666	0.222	0.232	0.821
rs324015	STAT6	STAT6_2_gene	KIF5A	-0.157	0.195	0.204	0.821
rs324015	STAT6	STAT6_2_gene	MARS	-0.0641	0.264	0.275	0.821
rs324015	STAT6	STAT6_2_gene	NAB2	0.0805	0.221	0.231	0.821
rs324015	STAT6	STAT6_3_gene	DCTN2	-0.0632	0.276	0.269	0.821
rs324015	STAT6	STAT6_3_gene	MBD6	-0.0639	0.288	0.281	0.821
rs324015	STAT6	STAT6_3_gene	NAB2	0.0784	0.263	0.256	0.821
rs9882911	TRANK1	TRANK1_2_gene	MLH1	0.0911	0.264	0.26	0.821
rs9882911	TRANK1	TRANK1_3_gene	LRRFIP2	0.0485	0.251	0.251	0.821
rs2027349	VPS45	VPS45_2_gene	TARS2	-0.0473	0.245	0.238	0.821
rs2027349	VPS45	VPS45_3_gene	ECM1	-0.422	0.246	0.253	0.821
rs2027349	VPS45	VPS45_3_gene	MRPS21	-0.0924	0.24	0.248	0.821
rs3861678	LINC00637	LINC00637_2_gene	PPP1R13B	0.0768	0.294	0.286	0.822
rs7148456	BAG5	BAG5_2_gene	APOPT1	0.054	0.282	0.297	0.824
rs520843	GALNT10	GALNT10_2_gene	FAM114A2	0.0633	0.311	0.301	0.824
rs12716973	KCTD13	KCTD13_3_gene	KIF22	-0.229	0.296	0.294	0.824
rs12716973	KCTD13	KCTD13_3_gene	TMEM219	-0.11	0.301	0.299	0.824
rs2192932	KMT2E	KMT2E_2_gene	KMT2E	-0.0977	0.301	0.3	0.824
rs186132169	NGEF	NGEF_1_gene	EIF4E2	0.111	0.305	0.301	0.824
rs9882911	TRANK1	TRANK1_3_gene	GOLGA4	0.0531	0.294	0.294	0.824
rs2027349	VPS45	VPS45_1_gene	PLEKHO1	0.102	0.297	0.296	0.824
rs2027349	VPS45	VPS45_3_gene	TARS2	-0.0939	0.292	0.299	0.824
rs2027349	VPS45	VPS45_1_gene	RPRD2	0.104	0.304	0.303	0.825
rs7170068	CHRNA3	CHRNA3_2_gene	CHRNA5	0.104	0.302	0.306	0.829
rs12895055	BCL11B	BCL11B_3_gene	CYP46A1	0.122	0.307	0.312	0.835
rs324015	STAT6	STAT6_2_gene	DDIT3	0.12	0.3	0.311	0.835
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA10	0.0561	0.322	0.315	0.838
rs520843	GALNT10	GALNT10_1_gene	MFAP3	-0.0543	0.322	0.319	0.845
rs324017	NAB2	NAB2_3_gene	DDIT3	0.15	0.321	0.324	0.846
rs10933	PBRM1	PBRM1_2_gene	SMIM4	0.0979	0.325	0.324	0.846
rs4151680	PCDHA123	PCDHA123_1_gene	HBEGF	0.231	0.331	0.324	0.846
rs12716973	KCTD13	KCTD13_2_gene	INO80E	0.0759	0.333	0.331	0.851
rs324015	STAT6	STAT6_3_gene	NACA	-0.0433	0.338	0.331	0.851
rs2027349	VPS45	VPS45_2_gene	OTUD7B	-0.0431	0.337	0.329	0.851
rs7170068	CHRNA3	CHRNA3_2_gene	IREB2	0.0779	0.333	0.337	0.861
rs2192932	KMT2E	KMT2E_1_gene	SRPK2	0.146	0.344	0.341	0.866
rs12716973	KCTD13	KCTD13_3_gene	FAM57B	-0.233	0.345	0.344	0.87
rs324017	NAB2	NAB2_2_gene	DCTN2	-0.0675	0.345	0.348	0.87
rs324017	NAB2	NAB2_3_gene	PIP4K2C	-0.0709	0.345	0.349	0.87
rs4151680	PCDHA123	PCDHA123_1_gene	SRA1	0.0534	0.355	0.348	0.87
rs301791	RERE	RERE_2_gene	PARK7	0.0434	0.357	0.354	0.878
rs12716973	KCTD13	KCTD13_2_gene	HIRIP3	-0.0931	0.36	0.358	0.884
rs7170068	CHRNA3	CHRNA3_1_gene	CHRNA5	0.116	0.379	0.364	0.885
rs520843	GALNT10	GALNT10_2_gene	SAP30L	0.0534	0.374	0.364	0.885
rs17200916	LOC105376975	LOC105376975_3_gene	TBC1D5	-0.0729	0.368	0.369	0.885
rs324017	NAB2	NAB2_1_gene	BAZ2A	0.0578	0.378	0.368	0.885
rs324015	STAT6	STAT6_2_gene	NACA	0.0393	0.354	0.366	0.885
rs2027349	VPS45	VPS45_1_gene	ECM1	0.329	0.367	0.366	0.885
rs7148456	BAG5	BAG5_2_gene	ZFYVE21	0.0468	0.356	0.371	0.886
rs186132169	NGEF	NGEF_3_gene	ECEL1	0.567	0.386	0.377	0.886
rs9882911	TRANK1	TRANK1_2_gene	EPM2AIP1	0.0829	0.378	0.376	0.886
rs2027349	VPS45	VPS45_2_gene	SV2A	-0.0773	0.383	0.375	0.886
rs324015	STAT6	STAT6_3_gene	PRIM1	-0.0663	0.386	0.379	0.888
rs2192932	KMT2E	KMT2E_3_gene	PUS7	-0.0604	0.385	0.383	0.894
rs12895055	BCL11B	BCL11B_3_gene	CCDC85C	-0.082	0.382	0.388	0.901
rs10933	PBRM1	PBRM1_2_gene	SPCS1	0.0733	0.394	0.394	0.906
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	NMB	0.105	0.39	0.394	0.906
rs7170068	CHRNA3	CHRNA3_3_gene	PSMA4	0.0705	0.412	0.406	0.91
rs12716973	KCTD13	KCTD13_1_gene	TMEM219	0.0515	0.405	0.409	0.91
rs12716973	KCTD13	KCTD13_2_gene	CD2BP2	0.0656	0.413	0.412	0.91
rs324017	NAB2	NAB2_2_gene	R3HDM2	-0.0705	0.403	0.407	0.91
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB16	-0.0631	0.406	0.399	0.91
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB16	-0.0511	0.417	0.409	0.91
rs301791	RERE	RERE_2_gene	SLC45A1	-0.0638	0.413	0.411	0.91
rs2027349	VPS45	VPS45_1_gene	OTUD7B	-0.0821	0.405	0.403	0.91
rs2027349	VPS45	VPS45_1_gene	PRPF3	-0.0855	0.404	0.402	0.91
rs7148456	BAG5	BAG5_2_gene	TRMT61A	-0.04	0.438	0.452	0.921
rs7148456	BAG5	BAG5_3_gene	KLC1	-0.118	0.409	0.424	0.921
rs7170068	CHRNA3	CHRNA3_1_gene	ADAMTS7	-0.0836	0.451	0.436	0.921
rs7170068	CHRNA3	CHRNA3_2_gene	WDR61	0.0532	0.459	0.462	0.921
rs520843	GALNT10	GALNT10_2_gene	MFAP3	0.0477	0.45	0.442	0.921
rs520843	GALNT10	GALNT10_3_gene	FAM114A2	0.0368	0.455	0.461	0.921
rs12716973	KCTD13	KCTD13_1_gene	MAPK3	-0.0524	0.461	0.464	0.921
rs12716973	KCTD13	KCTD13_1_gene	SEZ6L2	-0.113	0.43	0.434	0.921
rs3861678	LINC00637	LINC00637_1_gene	APOPT1	-0.0409	0.439	0.439	0.921
rs7936858	LOC100507431	LOC100507431_2_gene	SNX19	0.0538	0.459	0.451	0.921
rs7936858	LOC100507431	LOC100507431_3_gene	SNX19	-0.039	0.442	0.445	0.921
rs324017	NAB2	NAB2_2_gene	NAB2	0.0638	0.458	0.463	0.921
rs324017	NAB2	NAB2_3_gene	NXPH4	0.175	0.462	0.464	0.921
rs10933	PBRM1	PBRM1_1_gene	NISCH	0.0822	0.461	0.459	0.921
rs10933	PBRM1	PBRM1_1_gene	SPCS1	0.0725	0.422	0.419	0.921
rs10933	PBRM1	PBRM1_2_gene	NT5DC2	0.0953	0.459	0.458	0.921
rs4151680	PCDHA123	PCDHA123_1_gene	HARS2	0.0389	0.456	0.448	0.921
rs4151680	PCDHA123	PCDHA123_2_gene	APBB3	0.0393	0.452	0.444	0.921
rs4151680	PCDHA123	PCDHA123_2_gene	ZMAT2	-0.0337	0.441	0.433	0.921
rs6071578	PPP1R16B	PPP1R16B_1_gene	RALGAPB	0.0449	0.409	0.422	0.921
rs301791	RERE	RERE_3_gene	SLC45A1	-0.0692	0.426	0.43	0.921
rs324015	STAT6	STAT6_1_gene	MARS	0.0505	0.45	0.45	0.921
rs324015	STAT6	STAT6_3_gene	R3HDM2	-0.0509	0.459	0.453	0.921
rs2027349	VPS45	VPS45_1_gene	APH1A	0.0796	0.448	0.447	0.921
rs2027349	VPS45	VPS45_1_gene	SV2A	-0.153	0.431	0.43	0.921
rs2027349	VPS45	VPS45_2_gene	CA14	0.0874	0.462	0.454	0.921
rs7148456	BAG5	BAG5_1_gene	KLC1	-0.0699	0.515	0.509	0.921
rs7148456	BAG5	BAG5_3_gene	APOPT1	0.0545	0.495	0.508	0.921
rs7148456	BAG5	BAG5_3_gene	EIF5	0.0762	0.488	0.502	0.921
rs7170068	CHRNA3	CHRNA3_2_gene	CRABP1	1.3	0.476	0.48	0.921
rs7170068	CHRNA3	CHRNA3_3_gene	CHRNA5	0.0822	0.479	0.474	0.921
rs520843	GALNT10	GALNT10_2_gene	GALNT10	-0.05	0.521	0.513	0.921
rs12716973	KCTD13	KCTD13_1_gene	TBC1D10B	-0.0433	0.506	0.509	0.921
rs12716973	KCTD13	KCTD13_2_gene	CORO1A	0.0907	0.494	0.493	0.921
rs3861678	LINC00637	LINC00637_1_gene	KLC1	0.0641	0.5	0.501	0.921
rs3861678	LINC00637	LINC00637_3_gene	MARK3	-0.0355	0.482	0.481	0.921
rs324017	NAB2	NAB2_1_gene	DCTN2	0.041	0.494	0.484	0.921
rs324017	NAB2	NAB2_1_gene	MARS	-0.042	0.505	0.496	0.921
rs324017	NAB2	NAB2_2_gene	PIP4K2C	-0.0517	0.493	0.497	0.921
rs324017	NAB2	NAB2_2_gene	PRIM1	0.0661	0.481	0.486	0.921
rs324017	NAB2	NAB2_2_gene	PTGES3	0.052	0.489	0.493	0.921
rs186132169	NGEF	NGEF_3_gene	TIGD1	-0.095	0.491	0.482	0.921
rs10933	PBRM1	PBRM1_1_gene	NEK4	-0.0697	0.512	0.511	0.921
rs10933	PBRM1	PBRM1_1_gene	SFMBT1	-0.073	0.505	0.504	0.921
rs10933	PBRM1	PBRM1_2_gene	BAP1	0.0631	0.505	0.505	0.921
rs10933	PBRM1	PBRM1_3_gene	BAP1	0.0671	0.502	0.497	0.921
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA12	0.0395	0.52	0.512	0.921
rs4151680	PCDHA123	PCDHA123_3_gene	HARS	0.0282	0.502	0.497	0.921
rs4151680	PCDHA123	PCDHA123_3_gene	SLC35A4	-0.0265	0.494	0.49	0.921
rs324015	STAT6	STAT6_1_gene	R3HDM2	0.0496	0.508	0.509	0.921
rs324015	STAT6	STAT6_3_gene	NXPH4	0.131	0.499	0.493	0.921
rs2027349	VPS45	VPS45_1_gene	SF3B4	-0.0662	0.473	0.472	0.921
rs2027349	VPS45	VPS45_3_gene	PRPF3	0.0717	0.482	0.49	0.921
rs7170068	CHRNA3	CHRNA3_1_gene	CRABP1	-1.42	0.553	0.541	0.923
rs7170068	CHRNA3	CHRNA3_3_gene	WDR61	-0.0505	0.542	0.539	0.923
rs12716973	KCTD13	KCTD13_2_gene	ZNF771	-0.0492	0.552	0.551	0.923
rs12716973	KCTD13	KCTD13_3_gene	DCTPP1	0.0778	0.527	0.526	0.923
rs12716973	KCTD13	KCTD13_3_gene	TAOK2	-0.0665	0.527	0.527	0.923
rs12716973	KCTD13	KCTD13_3_gene	ZNF48	0.0754	0.536	0.535	0.923
rs3861678	LINC00637	LINC00637_3_gene	CKB	0.0682	0.551	0.551	0.923
rs3861678	LINC00637	LINC00637_3_gene	KLC1	0.0515	0.551	0.551	0.923
rs324017	NAB2	NAB2_1_gene	LRP1	0.0401	0.558	0.55	0.923
rs324017	NAB2	NAB2_1_gene	NAB2	-0.0418	0.563	0.554	0.923
rs324017	NAB2	NAB2_3_gene	PTGES3	0.0448	0.55	0.551	0.923
rs10933	PBRM1	PBRM1_2_gene	ALAS1	-0.0579	0.553	0.553	0.923
rs10933	PBRM1	PBRM1_2_gene	PHF7	0.0644	0.529	0.529	0.923
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA12	0.0469	0.526	0.518	0.923
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB14	-0.0352	0.553	0.547	0.923
rs4151680	PCDHA123	PCDHA123_3_gene	IK	-0.03	0.559	0.554	0.923
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB10	0.0375	0.557	0.553	0.923
rs4151680	PCDHA123	PCDHA123_3_gene	ZMAT2	0.0239	0.549	0.545	0.923
rs6071578	PPP1R16B	PPP1R16B_1_gene	ACTR5	-0.0365	0.508	0.52	0.923
rs6071578	PPP1R16B	PPP1R16B_3_gene	SNHG11	-0.0425	0.539	0.537	0.923
rs324015	STAT6	STAT6_3_gene	DDIT3	-0.0784	0.523	0.519	0.923
rs324015	STAT6	STAT6_3_gene	KIF5A	0.0756	0.559	0.554	0.923
rs12716973	KCTD13	KCTD13_2_gene	FAM57B	-0.108	0.56	0.559	0.923
rs3861678	LINC00637	LINC00637_2_gene	BAG5	-0.0382	0.568	0.562	0.923
rs10933	PBRM1	PBRM1_1_gene	ALAS1	-0.0592	0.563	0.562	0.923
rs4151680	PCDHA123	PCDHA123_2_gene	NDUFA2	-0.0234	0.563	0.557	0.923
rs10933	PBRM1	PBRM1_1_gene	PHF7	-0.0608	0.571	0.57	0.927
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA10	-0.0384	0.574	0.567	0.927
rs4151680	PCDHA123	PCDHA123_1_gene	SLC35A4	0.0285	0.579	0.572	0.927
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	WDR73	0.0483	0.585	0.572	0.927
rs186132169	NGEF	NGEF_1_gene	ECEL1	-0.3	0.581	0.577	0.933
rs2027349	VPS45	VPS45_1_gene	TARS2	0.0495	0.58	0.579	0.933
rs7148456	BAG5	BAG5_1_gene	CKB	-0.0713	0.617	0.611	0.933
rs12895055	BCL11B	BCL11B_2_gene	CYP46A1	-0.0416	0.601	0.606	0.933
rs7170068	CHRNA3	CHRNA3_2_gene	ADAMTS7	-0.0448	0.595	0.597	0.933
rs520843	GALNT10	GALNT10_2_gene	GRIA1	0.0446	0.61	0.605	0.933
rs12716973	KCTD13	KCTD13_2_gene	DCTPP1	-0.0476	0.607	0.606	0.933
rs12716973	KCTD13	KCTD13_2_gene	KIF22	-0.0904	0.584	0.583	0.933
rs12716973	KCTD13	KCTD13_3_gene	CDIPT	0.0609	0.608	0.607	0.933
rs12716973	KCTD13	KCTD13_3_gene	CORO1A	-0.089	0.613	0.611	0.933
rs12716973	KCTD13	KCTD13_3_gene	TBC1D10B	-0.0566	0.612	0.611	0.933
rs3861678	LINC00637	LINC00637_3_gene	APOPT1	-0.0243	0.613	0.612	0.933
rs7936858	LOC100507431	LOC100507431_1_gene	SNX19	-0.0468	0.604	0.6	0.933
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB10	-0.0373	0.594	0.588	0.933
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB2	-0.0284	0.596	0.592	0.933
rs6071578	PPP1R16B	PPP1R16B_1_gene	SNHG11	0.0331	0.581	0.592	0.933
rs301791	RERE	RERE_2_gene	ERRFI1	-0.041	0.609	0.608	0.933
rs301791	RERE	RERE_3_gene	ENO1	-0.0483	0.602	0.605	0.933
rs301791	RERE	RERE_3_gene	ERRFI1	-0.046	0.607	0.61	0.933
rs324015	STAT6	STAT6_1_gene	MBD6	-0.0347	0.597	0.598	0.933
rs2027349	VPS45	VPS45_1_gene	HIST2H2AC	0.098	0.615	0.614	0.934
rs324017	NAB2	NAB2_1_gene	MBD6	-0.0302	0.626	0.618	0.937
rs7148456	BAG5	BAG5_2_gene	CKB	0.0527	0.66	0.669	0.938
rs7148456	BAG5	BAG5_2_gene	EIF5	-0.0304	0.66	0.67	0.938
rs7148456	BAG5	BAG5_3_gene	MARK3	0.0355	0.673	0.682	0.938
rs7170068	CHRNA3	CHRNA3_1_gene	MORF4L1	0.0411	0.665	0.655	0.938
rs7170068	CHRNA3	CHRNA3_1_gene	WDR61	-0.0407	0.666	0.656	0.938
rs7170068	CHRNA3	CHRNA3_2_gene	MORF4L1	-0.0349	0.63	0.631	0.938
rs7170068	CHRNA3	CHRNA3_3_gene	ADAMTS7	0.0382	0.695	0.693	0.938
rs520843	GALNT10	GALNT10_2_gene	LARP1	-0.0284	0.651	0.645	0.938
rs12716973	KCTD13	KCTD13_2_gene	ZNF48	-0.0436	0.635	0.634	0.938
rs12716973	KCTD13	KCTD13_3_gene	KCTD13	0.0544	0.68	0.679	0.938
rs12716973	KCTD13	KCTD13_3_gene	MAZ	-0.0503	0.662	0.661	0.938
rs12716973	KCTD13	KCTD13_3_gene	QPRT	-0.0772	0.672	0.671	0.938
rs2192932	KMT2E	KMT2E_1_gene	PUS7	-0.0581	0.653	0.651	0.938
rs3861678	LINC00637	LINC00637_1_gene	MARK3	0.0256	0.645	0.645	0.938
rs3861678	LINC00637	LINC00637_1_gene	ZFYVE21	0.0225	0.673	0.673	0.938
rs17200916	LOC105376975	LOC105376975_2_gene	TBC1D5	0.0217	0.643	0.647	0.938
rs324017	NAB2	NAB2_1_gene	DDIT3	-0.0541	0.67	0.662	0.938
rs324017	NAB2	NAB2_2_gene	MARS	0.0327	0.663	0.667	0.938
rs324017	NAB2	NAB2_3_gene	KIF5A	-0.0735	0.643	0.645	0.938
rs324017	NAB2	NAB2_3_gene	LRP1	0.0324	0.691	0.693	0.938
rs324017	NAB2	NAB2_3_gene	PRIM1	-0.0436	0.642	0.644	0.938
rs186132169	NGEF	NGEF_1_gene	ATG16L1	0.0452	0.678	0.675	0.938
rs10933	PBRM1	PBRM1_1_gene	SMIM4	-0.0412	0.693	0.692	0.938
rs10933	PBRM1	PBRM1_3_gene	PHF7	-0.0515	0.633	0.631	0.938
rs10933	PBRM1	PBRM1_3_gene	RFT1	-0.0445	0.649	0.646	0.938
rs4151680	PCDHA123	PCDHA123_1_gene	IK	0.0284	0.675	0.669	0.938
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB9	-0.0315	0.692	0.686	0.938
rs4151680	PCDHA123	PCDHA123_1_gene	ZMAT2	0.0227	0.666	0.66	0.938
rs6071578	PPP1R16B	PPP1R16B_3_gene	ACTR5	0.03	0.636	0.635	0.938
rs301791	RERE	RERE_1_gene	RERE	-0.0258	0.637	0.635	0.938
rs301791	RERE	RERE_3_gene	PARK7	-0.0221	0.674	0.676	0.938
rs324015	STAT6	STAT6_2_gene	LRP1	0.0257	0.68	0.688	0.938
rs324015	STAT6	STAT6_2_gene	NXPH4	-0.0761	0.677	0.685	0.938
rs324015	STAT6	STAT6_2_gene	SHMT2	0.0317	0.634	0.643	0.938
rs324015	STAT6	STAT6_3_gene	PIP4K2C	0.0247	0.687	0.683	0.938
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	SEC11A	0.0434	0.677	0.682	0.938
rs2027349	VPS45	VPS45_1_gene	MRPS21	-0.0351	0.657	0.656	0.938
rs2027349	VPS45	VPS45_2_gene	HIST2H2BE	0.0263	0.638	0.631	0.938
rs2027349	VPS45	VPS45_2_gene	MRPS21	0.0166	0.645	0.638	0.938
rs2027349	VPS45	VPS45_3_gene	OTUD7B	0.0456	0.642	0.649	0.938
rs12716973	KCTD13	KCTD13_1_gene	DCTPP1	-0.0275	0.701	0.703	0.939
rs10933	PBRM1	PBRM1_2_gene	NISCH	-0.0406	0.702	0.702	0.939
rs324015	STAT6	STAT6_1_gene	DCTN2	0.0246	0.699	0.699	0.939
rs324015	STAT6	STAT6_1_gene	SHMT2	0.0296	0.703	0.703	0.939
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ZNF592	0.0325	0.706	0.696	0.939
rs10933	PBRM1	PBRM1_3_gene	GLT8D1	-0.0376	0.71	0.708	0.941
rs4151680	PCDHA123	PCDHA123_3_gene	ANKHD1	0.0148	0.71	0.708	0.941
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	SEC11A	0.0387	0.708	0.711	0.942
rs7148456	BAG5	BAG5_1_gene	PPP1R13B	-0.0267	0.726	0.722	0.953
rs324017	NAB2	NAB2_2_gene	LRP1	-0.0285	0.727	0.73	0.962
rs7148456	BAG5	BAG5_1_gene	EIF5	0.0212	0.797	0.793	0.963
rs7148456	BAG5	BAG5_3_gene	PPP1R13B	0.0359	0.725	0.733	0.963
rs7148456	BAG5	BAG5_3_gene	ZFYVE21	0.0235	0.77	0.777	0.963
rs12895055	BCL11B	BCL11B_1_gene	CCDC85C	-0.0344	0.732	0.737	0.963
rs7170068	CHRNA3	CHRNA3_1_gene	CTSH	0.0343	0.792	0.786	0.963
rs7170068	CHRNA3	CHRNA3_1_gene	IDH3A	0.0349	0.795	0.788	0.963
rs7170068	CHRNA3	CHRNA3_3_gene	CIB2	0.0415	0.786	0.785	0.963
rs7170068	CHRNA3	CHRNA3_3_gene	CTSH	-0.0315	0.783	0.782	0.963
rs520843	GALNT10	GALNT10_1_gene	GALNT10	-0.0182	0.788	0.786	0.963
rs12716973	KCTD13	KCTD13_2_gene	QPRT	0.0361	0.793	0.791	0.963
rs12716973	KCTD13	KCTD13_2_gene	TBC1D10B	-0.0228	0.786	0.785	0.963
rs12716973	KCTD13	KCTD13_2_gene	YPEL3	-0.0331	0.783	0.781	0.963
rs17200916	LOC105376975	LOC105376975_1_gene	TBC1D5	-0.0172	0.786	0.788	0.963
rs324017	NAB2	NAB2_1_gene	PTGES3	-0.0196	0.756	0.75	0.963
rs324017	NAB2	NAB2_2_gene	BAZ2A	-0.0269	0.731	0.734	0.963
rs186132169	NGEF	NGEF_3_gene	GIGYF2	0.0408	0.762	0.756	0.963
rs10933	PBRM1	PBRM1_2_gene	NEK4	0.0329	0.745	0.745	0.963
rs10933	PBRM1	PBRM1_2_gene	RFT1	-0.0245	0.791	0.791	0.963
rs10933	PBRM1	PBRM1_3_gene	SMIM4	-0.0341	0.746	0.744	0.963
rs4151680	PCDHA123	PCDHA123_1_gene	WDR55	0.0155	0.767	0.763	0.963
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB2	0.0157	0.788	0.784	0.963
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB5	0.0133	0.789	0.788	0.963
rs6071578	PPP1R16B	PPP1R16B_3_gene	RALGAPB	-0.0163	0.795	0.793	0.963
rs301791	RERE	RERE_1_gene	ERRFI1	-0.0162	0.789	0.788	0.963
rs301791	RERE	RERE_2_gene	ENO1	0.0247	0.766	0.765	0.963
rs301791	RERE	RERE_2_gene	RERE	-0.0203	0.779	0.777	0.963
rs324015	STAT6	STAT6_1_gene	KIF5A	-0.0437	0.757	0.757	0.963
rs324015	STAT6	STAT6_1_gene	LRP1	0.0212	0.77	0.769	0.963
rs324015	STAT6	STAT6_1_gene	NXPH4	0.0619	0.77	0.77	0.963
rs324015	STAT6	STAT6_1_gene	PIP4K2C	0.021	0.753	0.753	0.963
rs9882911	TRANK1	TRANK1_2_gene	LRRFIP2	-0.0241	0.769	0.768	0.963
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	WDR73	0.0342	0.75	0.753	0.963
rs2027349	VPS45	VPS45_2_gene	BOLA1	0.0123	0.773	0.768	0.963
rs12716973	KCTD13	KCTD13_1_gene	INO80E	-0.0156	0.797	0.798	0.963
rs12716973	KCTD13	KCTD13_3_gene	INO80E	0.0264	0.8	0.8	0.963
rs3861678	LINC00637	LINC00637_1_gene	CKB	-0.0322	0.798	0.798	0.963
rs12895055	BCL11B	BCL11B_1_gene	CYP46A1	0.0291	0.82	0.823	0.971
rs7170068	CHRNA3	CHRNA3_2_gene	CIB2	0.0299	0.822	0.823	0.971
rs7170068	CHRNA3	CHRNA3_3_gene	CRABP1	0.472	0.823	0.821	0.971
rs12716973	KCTD13	KCTD13_1_gene	CORO1A	-0.0213	0.835	0.836	0.971
rs12716973	KCTD13	KCTD13_1_gene	MVP	-0.0194	0.837	0.838	0.971
rs12716973	KCTD13	KCTD13_1_gene	PRRT2	0.0215	0.83	0.831	0.971
rs3861678	LINC00637	LINC00637_3_gene	TRMT61A	-0.01	0.838	0.839	0.971
rs324017	NAB2	NAB2_1_gene	KIF5A	-0.0272	0.839	0.835	0.971
rs186132169	NGEF	NGEF_1_gene	GIGYF2	-0.0242	0.828	0.826	0.971
rs10933	PBRM1	PBRM1_3_gene	TWF2	-0.022	0.83	0.828	0.971
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB2	0.0161	0.82	0.816	0.971
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB16	0.0139	0.81	0.809	0.971
rs324015	STAT6	STAT6_1_gene	DDIT3	0.0274	0.839	0.838	0.971
rs324015	STAT6	STAT6_2_gene	PRIM1	-0.0165	0.818	0.824	0.971
rs324015	STAT6	STAT6_3_gene	LRP1	0.0137	0.837	0.836	0.971
rs2027349	VPS45	VPS45_1_gene	HIST2H2BE	-0.0263	0.83	0.83	0.971
rs2027349	VPS45	VPS45_2_gene	SF3B4	0.00937	0.823	0.819	0.971
rs324017	NAB2	NAB2_1_gene	PIP4K2C	0.0118	0.852	0.849	0.981
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ZSCAN2	-0.0205	0.851	0.853	0.983
rs12895055	BCL11B	BCL11B_2_gene	CCDC85C	-0.0107	0.864	0.865	0.984
rs12895055	BCL11B	BCL11B_2_gene	SETD3	0.00587	0.905	0.906	0.984
rs520843	GALNT10	GALNT10_1_gene	GRIA1	0.0114	0.881	0.879	0.984
rs520843	GALNT10	GALNT10_1_gene	LARP1	0.00612	0.911	0.91	0.984
rs12716973	KCTD13	KCTD13_1_gene	CDIPT	-0.0087	0.9	0.9	0.984
rs12716973	KCTD13	KCTD13_1_gene	HIRIP3	-0.0126	0.872	0.873	0.984
rs12716973	KCTD13	KCTD13_1_gene	KIF22	-0.0154	0.904	0.904	0.984
rs12716973	KCTD13	KCTD13_2_gene	ASPHD1	0.0207	0.885	0.883	0.984
rs12716973	KCTD13	KCTD13_2_gene	CDIPT	0.0123	0.89	0.888	0.984
rs12716973	KCTD13	KCTD13_3_gene	ASPHD1	-0.0343	0.857	0.857	0.984
rs12716973	KCTD13	KCTD13_3_gene	PRRT2	0.0285	0.868	0.869	0.984
rs12716973	KCTD13	KCTD13_3_gene	SEZ6L2	0.0365	0.883	0.884	0.984
rs2192932	KMT2E	KMT2E_2_gene	SRPK2	0.00967	0.908	0.907	0.984
rs3861678	LINC00637	LINC00637_1_gene	BAG5	0.00695	0.91	0.911	0.984
rs3861678	LINC00637	LINC00637_2_gene	KLC1	0.0156	0.879	0.878	0.984
rs324017	NAB2	NAB2_2_gene	DDIT3	0.02	0.895	0.895	0.984
rs10933	PBRM1	PBRM1_3_gene	SPCS1	0.0102	0.91	0.91	0.984
rs4151680	PCDHA123	PCDHA123_2_gene	IK	-0.00656	0.907	0.905	0.984
rs4151680	PCDHA123	PCDHA123_3_gene	SRA1	-0.00719	0.869	0.869	0.984
rs6071578	PPP1R16B	PPP1R16B_2_gene	SNHG11	-0.0107	0.87	0.869	0.984
rs301791	RERE	RERE_1_gene	SLC45A1	-0.00696	0.906	0.907	0.984
rs324015	STAT6	STAT6_1_gene	BAZ2A	0.00801	0.908	0.908	0.984
rs324015	STAT6	STAT6_1_gene	NAB2	-0.00979	0.898	0.898	0.984
rs324015	STAT6	STAT6_1_gene	PTGES3	-0.0108	0.872	0.872	0.984
rs324015	STAT6	STAT6_3_gene	PTGES3	0.00875	0.886	0.885	0.984
rs9882911	TRANK1	TRANK1_2_gene	GOLGA4	-0.0137	0.889	0.888	0.984
rs9882911	TRANK1	TRANK1_3_gene	MLH1	-0.00543	0.897	0.896	0.984
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ZNF592	-0.0129	0.901	0.903	0.984
rs2027349	VPS45	VPS45_2_gene	PLEKHO1	0.0069	0.877	0.874	0.984
rs7148456	BAG5	BAG5_1_gene	ZFYVE21	-0.00582	0.923	0.922	0.985
rs7170068	CHRNA3	CHRNA3_2_gene	IDH3A	0.00984	0.923	0.923	0.985
rs3861678	LINC00637	LINC00637_1_gene	TRMT61A	0.00563	0.917	0.918	0.985
rs10933	PBRM1	PBRM1_2_gene	WDR82	0.0106	0.917	0.918	0.985
rs10933	PBRM1	PBRM1_3_gene	NEK4	-0.0101	0.925	0.925	0.985
rs4151680	PCDHA123	PCDHA123_2_gene	ANKHD1	0.00394	0.928	0.926	0.985
rs2027349	VPS45	VPS45_1_gene	C1orf54	-0.0229	0.926	0.926	0.985
rs2027349	VPS45	VPS45_2_gene	PRPF3	0.00492	0.916	0.914	0.985
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ZSCAN2	-0.00756	0.934	0.931	0.988
rs324017	NAB2	NAB2_3_gene	DCTN2	0.00572	0.936	0.937	0.992
rs7148456	BAG5	BAG5_1_gene	MARK3	0.00323	0.959	0.958	0.992
rs7170068	CHRNA3	CHRNA3_1_gene	CIB2	-0.00692	0.968	0.967	0.992
rs520843	GALNT10	GALNT10_1_gene	SAP30L	0.00342	0.948	0.947	0.992
rs520843	GALNT10	GALNT10_3_gene	GRIA1	-0.00371	0.957	0.958	0.992
rs12716973	KCTD13	KCTD13_1_gene	CD2BP2	-0.00165	0.979	0.979	0.992
rs12716973	KCTD13	KCTD13_1_gene	MAZ	-0.00327	0.961	0.961	0.992
rs12716973	KCTD13	KCTD13_1_gene	TAOK2	-0.00173	0.977	0.978	0.992
rs12716973	KCTD13	KCTD13_2_gene	SEPT1	0.006	0.944	0.943	0.992
rs2192932	KMT2E	KMT2E_1_gene	KMT2E	0.00838	0.962	0.961	0.992
rs2192932	KMT2E	KMT2E_2_gene	PUS7	-0.00287	0.967	0.967	0.992
rs3861678	LINC00637	LINC00637_2_gene	APOPT1	0.00171	0.976	0.975	0.992
rs324017	NAB2	NAB2_2_gene	NXPH4	-0.00847	0.972	0.972	0.992
rs324017	NAB2	NAB2_2_gene	SHMT2	-0.00306	0.972	0.972	0.992
rs324017	NAB2	NAB2_3_gene	BAZ2A	-0.0026	0.973	0.974	0.992
rs324017	NAB2	NAB2_3_gene	MARS	-0.00148	0.984	0.985	0.992
rs324017	NAB2	NAB2_3_gene	SHMT2	-0.00164	0.985	0.985	0.992
rs10933	PBRM1	PBRM1_1_gene	RFT1	0.00567	0.953	0.953	0.992
rs10933	PBRM1	PBRM1_1_gene	TWF2	0.00691	0.946	0.945	0.992
rs10933	PBRM1	PBRM1_2_gene	GLT8D1	-0.00341	0.972	0.972	0.992
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB14	0.00436	0.951	0.951	0.992
rs4151680	PCDHA123	PCDHA123_2_gene	HARS	-0.00119	0.979	0.98	0.992
rs324015	STAT6	STAT6_3_gene	BAZ2A	-0.00478	0.94	0.94	0.992
rs324015	STAT6	STAT6_3_gene	SHMT2	-0.00186	0.979	0.979	0.992
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	NMB	0.00282	0.982	0.982	0.992
rs2027349	VPS45	VPS45_3_gene	PLEKHO1	0.00167	0.986	0.986	0.992
rs2027349	VPS45	VPS45_2_gene	HIST2H2AC	-0.00123	0.989	0.989	0.993
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB9	0.000211	0.997	0.997	0.998
rs324015	STAT6	STAT6_1_gene	NACA	0.000111	0.998	0.998	0.998

cis pairs that passed FDR < 0.1: 5 

cis pairs that have an empirical p values < 0.05: 43

---

1 Mb cis gene result

formatted.df = cis_summary$cis_summary_1Mb
fdr_num = dim(filter(formatted.df, pval_adj_cis < 0.1))[1]
pval_num = dim(filter(formatted.df, empirical_pval < 0.05))[1]
formatted.df = select(formatted.df, c('SNP','locus','gRNA','gene','beta','pval',
                                        'empirical_pval','pval_adj_cis')) %>% arrange(pval_adj_cis)
formatted.df[,5:8] = signif(formatted.df[,5:8], digits = 3)
mutate(formatted.df, 
       beta = cell_spec(beta, "html", color = ifelse(beta < 0, "red", "blue")),
       pval = cell_spec(pval, "html", color = ifelse(pval < 0.05, "orange", "black")),
       pval_adj_cis = cell_spec(pval_adj_cis, "html", color = ifelse(pval_adj_cis < 0.1, "red", "black")),
       empirical_pval = cell_spec(empirical_pval, "html", color = ifelse(empirical_pval < 0.05, "orange", "black"))) %>% 
  kable(format = "html", escape = F) %>%
  kable_styling() %>% scroll_box(width = "100%", height = "400px")

SNP	locus	gRNA	gene	beta	pval	empirical_pval	pval_adj_cis
rs2027349	VPS45	VPS45_2_gene	VPS45	-0.448	3.68e-25	2.44e-06	0.00225
rs2027349	VPS45	VPS45_3_gene	VPS45	-0.505	1.04e-07	1.46e-05	0.00675
rs7148456	BAG5	BAG5_2_gene	BAG5	-0.233	7.28e-05	0.000239	0.0552
rs10933	PBRM1	PBRM1_3_gene	PBRM1	-0.502	5.55e-05	0.000185	0.0552
rs10933	PBRM1	PBRM1_3_gene	GNL3	-0.443	0.000143	0.000351	0.0648
rs324015	STAT6	STAT6_2_gene	MYL6	0.293	0.000518	0.000677	0.104
rs10933	PBRM1	PBRM1_2_gene	PBRM1	-0.385	0.00108	0.00131	0.151
rs324015	STAT6	STAT6_1_gene	MYL6B	-0.233	0.00105	0.00128	0.151
rs301791	RERE	RERE_2_gene	SPSB1	0.234	0.00229	0.00221	0.227
rs324015	STAT6	STAT6_1_gene	MYL6	0.303	0.00209	0.00246	0.227
rs324017	NAB2	NAB2_2_gene	OS9	-0.202	0.00291	0.00332	0.256
rs4151680	PCDHA123	PCDHA123_3_gene	WDR55	0.118	0.00295	0.00317	0.256
rs4151680	PCDHA123	PCDHA123_2_gene	HARS2	-0.121	0.00528	0.00481	0.261
rs324015	STAT6	STAT6_2_gene	R3HDM2	-0.191	0.00304	0.00383	0.261
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	SEC11A	0.237	0.0059	0.00473	0.261
rs2027349	VPS45	VPS45_1_gene	VPS45	-0.274	0.00411	0.00474	0.261
rs2027349	VPS45	VPS45_2_gene	ECM1	0.463	0.00532	0.00433	0.261
rs2027349	VPS45	VPS45_3_gene	ANP32E	0.711	0.00402	0.00534	0.274
rs12716973	KCTD13	KCTD13_2_gene	TMEM219	0.215	0.00719	0.00872	0.358
rs4151680	PCDHA123	PCDHA123_2_gene	HBEGF	0.516	0.00901	0.00834	0.358
rs324015	STAT6	STAT6_2_gene	PTGES3	-0.153	0.0075	0.00891	0.358
rs324015	STAT6	STAT6_3_gene	ZC3H10	-0.167	0.00748	0.00742	0.358
rs2027349	VPS45	VPS45_2_gene	APH1A	0.123	0.0101	0.00851	0.358
rs12716973	KCTD13	KCTD13_2_gene	KCTD13	-0.25	0.0119	0.0138	0.366
rs12716973	KCTD13	KCTD13_3_gene	ALDOA	0.265	0.00998	0.0111	0.366
rs12716973	KCTD13	KCTD13_3_gene	CCDC189	0.311	0.0102	0.0114	0.366
rs3861678	LINC00637	LINC00637_2_gene	CKB	-0.344	0.0117	0.0105	0.366
rs3861678	LINC00637	LINC00637_2_gene	TRAF3	-0.163	0.0122	0.0109	0.366
rs3861678	LINC00637	LINC00637_3_gene	CDC42BPB	0.135	0.0147	0.014	0.366
rs7936858	LOC100507431	LOC100507431_3_gene	NTM	0.417	0.0132	0.0146	0.366
rs4151680	PCDHA123	PCDHA123_1_gene	CYSTM1	0.241	0.016	0.0145	0.366
rs4151680	PCDHA123	PCDHA123_2_gene	WDR55	-0.106	0.0144	0.0133	0.366
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA12	0.139	0.0128	0.0124	0.366
rs324015	STAT6	STAT6_1_gene	TSFM	0.147	0.0103	0.0106	0.366
rs324015	STAT6	STAT6_3_gene	DTX3	-0.168	0.0142	0.0138	0.366
rs2027349	VPS45	VPS45_2_gene	C1orf54	0.267	0.0173	0.0147	0.366
rs2027349	VPS45	VPS45_3_gene	HIST2H2BE	-0.314	0.0103	0.0127	0.366
rs10933	PBRM1	PBRM1_2_gene	SFMBT1	-0.25	0.0164	0.0157	0.383
rs324017	NAB2	NAB2_1_gene	NACA	-0.109	0.0191	0.0168	0.397
rs324017	NAB2	NAB2_2_gene	MYL6B	-0.191	0.0171	0.0173	0.399
rs12895055	BCL11B	BCL11B_1_gene	CCNK	-0.198	0.0175	0.0193	0.436
rs10933	PBRM1	PBRM1_1_gene	NT5DC2	0.312	0.0209	0.02	0.439
rs7170068	CHRNA3	CHRNA3_2_gene	TBC1D2B	0.206	0.0211	0.0218	0.442
rs12716973	KCTD13	KCTD13_3_gene	HIRIP3	0.313	0.0203	0.0208	0.442
rs324017	NAB2	NAB2_1_gene	ESYT1	0.133	0.0246	0.0219	0.442
rs2027349	VPS45	VPS45_3_gene	MLLT11	-0.639	0.0192	0.022	0.442
rs12895055	BCL11B	BCL11B_3_gene	SETD3	0.168	0.023	0.0248	0.458
rs10933	PBRM1	PBRM1_2_gene	TKT	0.222	0.0262	0.0247	0.458
rs10933	PBRM1	PBRM1_3_gene	POC1A	-0.346	0.0253	0.0235	0.458
rs4151680	PCDHA123	PCDHA123_2_gene	SLC35A4	-0.0944	0.0263	0.0246	0.458
rs12716973	KCTD13	KCTD13_2_gene	MAPK3	-0.206	0.0251	0.027	0.482
rs4151680	PCDHA123	PCDHA123_1_gene	RELL2	0.156	0.0291	0.0271	0.482
rs12716973	KCTD13	KCTD13_1_gene	PHKG2	-0.136	0.0284	0.0284	0.495
rs324017	NAB2	NAB2_2_gene	MBD6	-0.161	0.0296	0.0292	0.5
rs7148456	BAG5	BAG5_3_gene	TRMT61A	-0.183	0.0253	0.031	0.507
rs12716973	KCTD13	KCTD13_2_gene	ZNF768	0.177	0.0287	0.0307	0.507
rs324015	STAT6	STAT6_2_gene	ESYT1	0.118	0.0278	0.0313	0.507
rs3861678	LINC00637	LINC00637_3_gene	EIF5	-0.14	0.0341	0.0333	0.528
rs324017	NAB2	NAB2_2_gene	ATP23	0.143	0.034	0.0337	0.528
rs2192932	KMT2E	KMT2E_3_gene	SRPK2	-0.175	0.0353	0.0344	0.53
rs12716973	KCTD13	KCTD13_1_gene	SEPHS2	-0.183	0.036	0.0361	0.532
rs324017	NAB2	NAB2_2_gene	MYL6	0.232	0.0363	0.0363	0.532
rs2027349	VPS45	VPS45_2_gene	RPRD2	-0.0945	0.0408	0.0359	0.532
rs7148456	BAG5	BAG5_1_gene	APOPT1	-0.121	0.0431	0.0395	0.57
rs4151680	PCDHA123	PCDHA123_3_gene	APBB3	0.0968	0.0424	0.0408	0.571
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA10	-0.105	0.0422	0.0406	0.571
rs7148456	BAG5	BAG5_3_gene	CKB	-0.397	0.0372	0.0444	0.581
rs324015	STAT6	STAT6_1_gene	PRIM1	-0.168	0.044	0.0437	0.581
rs324015	STAT6	STAT6_2_gene	METTL1	0.114	0.0406	0.0446	0.581
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	NMB	0.198	0.0501	0.0427	0.581
rs2027349	VPS45	VPS45_2_gene	ANP32E	0.222	0.0493	0.0442	0.581
rs324015	STAT6	STAT6_2_gene	RPL41	0.15	0.0453	0.0498	0.639
rs12716973	KCTD13	KCTD13_2_gene	PPP4C	-0.137	0.0504	0.0517	0.652
rs10933	PBRM1	PBRM1_2_gene	TWF2	0.186	0.0543	0.0522	0.652
rs7148456	BAG5	BAG5_2_gene	RCOR1	-0.11	0.0453	0.0532	0.655
rs7936858	LOC100507431	LOC100507431_2_gene	NTM	0.454	0.0598	0.0538	0.655
rs7170068	CHRNA3	CHRNA3_3_gene	CHRNA3	-0.686	0.0572	0.0554	0.664
rs12895055	BCL11B	BCL11B_3_gene	CCNK	-0.149	0.0569	0.059	0.69
rs12716973	KCTD13	KCTD13_3_gene	ZNF629	-0.215	0.06	0.0588	0.69
rs7936858	LOC100507431	LOC100507431_1_gene	ZBTB44	-0.185	0.0612	0.0609	0.703
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB9	0.122	0.0659	0.0625	0.705
rs324015	STAT6	STAT6_2_gene	SMARCC2	-0.127	0.0577	0.0623	0.705
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ZNF592	0.193	0.0631	0.0634	0.706
rs7148456	BAG5	BAG5_3_gene	BAG5	-0.175	0.0602	0.0691	0.717
rs12716973	KCTD13	KCTD13_2_gene	SEZ6L2	0.342	0.0661	0.0671	0.717
rs4151680	PCDHA123	PCDHA123_1_gene	NDUFA2	0.0874	0.0732	0.0688	0.717
rs324015	STAT6	STAT6_2_gene	DTX3	-0.12	0.0637	0.0684	0.717
rs2027349	VPS45	VPS45_3_gene	HIST2H2AC	-0.362	0.062	0.067	0.717
rs2027349	VPS45	VPS45_3_gene	SF3B4	0.171	0.063	0.068	0.717
rs3861678	LINC00637	LINC00637_1_gene	PPP1R13B	-0.123	0.0687	0.07	0.719
rs7148456	BAG5	BAG5_2_gene	KLC1	-0.167	0.0644	0.0742	0.736
rs520843	GALNT10	GALNT10_3_gene	MFAP3	0.0889	0.0736	0.0756	0.736
rs10933	PBRM1	PBRM1_3_gene	RRP9	0.192	0.0785	0.0738	0.736
rs324015	STAT6	STAT6_2_gene	PIP4K2C	-0.104	0.071	0.0763	0.736
rs2027349	VPS45	VPS45_1_gene	ARNT	-0.161	0.0745	0.0735	0.736
rs2027349	VPS45	VPS45_3_gene	SV2A	-0.35	0.0712	0.0765	0.736
rs4151680	PCDHA123	PCDHA123_1_gene	HARS	0.0964	0.0822	0.0775	0.738
rs7148456	BAG5	BAG5_1_gene	TRMT61A	0.106	0.0847	0.0794	0.739
rs12716973	KCTD13	KCTD13_3_gene	ZNF768	0.188	0.0813	0.079	0.739
rs3861678	LINC00637	LINC00637_2_gene	MARK3	-0.104	0.0846	0.08	0.739
rs520843	GALNT10	GALNT10_1_gene	FAM114A2	0.0937	0.0846	0.0816	0.74
rs4151680	PCDHA123	PCDHA123_1_gene	APBB3	0.108	0.086	0.0812	0.74
rs2192932	KMT2E	KMT2E_1_gene	ORC5	-0.217	0.0894	0.0841	0.754
rs7170068	CHRNA3	CHRNA3_3_gene	IDH3A	-0.201	0.0885	0.0856	0.76
rs12716973	KCTD13	KCTD13_1_gene	BCL7C	0.125	0.0876	0.088	0.76
rs4151680	PCDHA123	PCDHA123_3_gene	HARS2	-0.0669	0.0907	0.0866	0.76
rs2027349	VPS45	VPS45_3_gene	CA14	0.452	0.0812	0.0872	0.76
rs12895055	BCL11B	BCL11B_2_gene	CCNK	-0.0891	0.0861	0.0922	0.768
rs12716973	KCTD13	KCTD13_2_gene	PRRT2	-0.218	0.092	0.092	0.768
rs10933	PBRM1	PBRM1_1_gene	GLT8D1	0.168	0.0953	0.0922	0.768
rs4151680	PCDHA123	PCDHA123_1_gene	PFDN1	-0.0851	0.0966	0.0915	0.768
rs7170068	CHRNA3	CHRNA3_2_gene	PSMA4	0.125	0.0931	0.095	0.774
rs12716973	KCTD13	KCTD13_1_gene	ZNF688	-0.107	0.0951	0.0955	0.774
rs9882911	TRANK1	TRANK1_3_gene	EPM2AIP1	-0.0804	0.0965	0.0951	0.774
rs12895055	BCL11B	BCL11B_1_gene	EVL	-0.217	0.107	0.111	0.792
rs7170068	CHRNA3	CHRNA3_2_gene	CHRNA3	-0.518	0.097	0.099	0.792
rs12716973	KCTD13	KCTD13_1_gene	ALDOA	0.0977	0.103	0.103	0.792
rs12716973	KCTD13	KCTD13_1_gene	ZNF48	0.116	0.101	0.102	0.792
rs12716973	KCTD13	KCTD13_2_gene	ALDOA	0.125	0.106	0.105	0.792
rs12716973	KCTD13	KCTD13_3_gene	FBRS	-0.18	0.112	0.109	0.792
rs12716973	KCTD13	KCTD13_3_gene	MVP	-0.257	0.113	0.11	0.792
rs3861678	LINC00637	LINC00637_1_gene	TRAF3	0.0981	0.103	0.104	0.792
rs3861678	LINC00637	LINC00637_3_gene	TRAF3	-0.0872	0.111	0.11	0.792
rs324017	NAB2	NAB2_2_gene	CDK4	0.202	0.106	0.106	0.792
rs10933	PBRM1	PBRM1_2_gene	PCBP4	-0.354	0.104	0.102	0.792
rs10933	PBRM1	PBRM1_3_gene	WDR82	0.172	0.113	0.106	0.792
rs324015	STAT6	STAT6_1_gene	COQ10A	-0.124	0.113	0.111	0.792
rs324015	STAT6	STAT6_2_gene	SPRYD4	-0.0863	0.103	0.11	0.792
rs2027349	VPS45	VPS45_1_gene	MCL1	-0.179	0.102	0.101	0.792
rs2027349	VPS45	VPS45_3_gene	RPRD2	0.166	0.101	0.107	0.792
rs324017	NAB2	NAB2_3_gene	MBD6	0.117	0.111	0.112	0.792
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHGB6	-0.0945	0.119	0.114	0.797
rs324017	NAB2	NAB2_2_gene	PA2G4	0.133	0.116	0.116	0.801
rs10933	PBRM1	PBRM1_1_gene	GNL3	0.179	0.122	0.118	0.801
rs2027349	VPS45	VPS45_1_gene	ANP32E	0.387	0.12	0.118	0.801
rs2027349	VPS45	VPS45_1_gene	BOLA1	-0.145	0.12	0.119	0.801
rs2027349	VPS45	VPS45_3_gene	C1orf54	0.39	0.112	0.119	0.801
rs7148456	BAG5	BAG5_1_gene	CDC42BPB	-0.105	0.127	0.121	0.807
rs324017	NAB2	NAB2_2_gene	TIMELESS	0.135	0.122	0.121	0.807
rs2192932	KMT2E	KMT2E_3_gene	KMT2E	-0.143	0.128	0.125	0.808
rs324017	NAB2	NAB2_1_gene	SHMT2	0.11	0.132	0.123	0.808
rs4151680	PCDHA123	PCDHA123_3_gene	HBEGF	0.274	0.129	0.124	0.808
rs324015	STAT6	STAT6_3_gene	MARS	0.0926	0.13	0.125	0.808
rs12716973	KCTD13	KCTD13_1_gene	ASPHD1	-0.169	0.128	0.13	0.81
rs324017	NAB2	NAB2_1_gene	NABP2	0.087	0.138	0.129	0.81
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB5	0.082	0.132	0.127	0.81
rs6071578	PPP1R16B	PPP1R16B_2_gene	CTNNBL1	-0.079	0.132	0.13	0.81
rs324015	STAT6	STAT6_2_gene	MBD6	-0.0876	0.121	0.128	0.81
rs12716973	KCTD13	KCTD13_3_gene	PPP4C	0.139	0.136	0.133	0.817
rs12716973	KCTD13	KCTD13_3_gene	ZNF689	-0.176	0.136	0.132	0.817
rs12895055	BCL11B	BCL11B_1_gene	SETD3	0.119	0.132	0.138	0.836
rs7170068	CHRNA3	CHRNA3_3_gene	IREB2	-0.136	0.143	0.138	0.836
rs12716973	KCTD13	KCTD13_1_gene	FAM57B	-0.214	0.138	0.139	0.836
rs7936858	LOC100507431	LOC100507431_3_gene	APLP2	0.108	0.138	0.139	0.836
rs7148456	BAG5	BAG5_3_gene	RCOR1	0.131	0.132	0.144	0.838
rs7170068	CHRNA3	CHRNA3_3_gene	MORF4L1	-0.119	0.154	0.149	0.838
rs3861678	LINC00637	LINC00637_1_gene	SIVA1	0.115	0.147	0.148	0.838
rs7936858	LOC100507431	LOC100507431_3_gene	NFRKB	-0.0739	0.144	0.146	0.838
rs324017	NAB2	NAB2_1_gene	NXPH4	0.285	0.155	0.144	0.838
rs324017	NAB2	NAB2_1_gene	OS9	0.0812	0.154	0.143	0.838
rs10933	PBRM1	PBRM1_1_gene	PBRM1	-0.176	0.154	0.15	0.838
rs10933	PBRM1	PBRM1_3_gene	ABHD14A	0.245	0.154	0.147	0.838
rs10933	PBRM1	PBRM1_3_gene	NISCH	-0.161	0.153	0.145	0.838
rs4151680	PCDHA123	PCDHA123_1_gene	PURA	0.0925	0.151	0.145	0.838
rs324015	STAT6	STAT6_3_gene	SMARCC2	-0.101	0.156	0.15	0.838
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	WDR73	0.155	0.146	0.147	0.838
rs186132169	NGEF	NGEF_1_gene	DIS3L2	-0.146	0.156	0.152	0.843
rs324015	STAT6	STAT6_3_gene	ESYT1	0.0803	0.16	0.154	0.849
rs12716973	KCTD13	KCTD13_1_gene	SEPT1	-0.0939	0.154	0.156	0.849
rs12716973	KCTD13	KCTD13_2_gene	MVP	0.172	0.159	0.158	0.849
rs324017	NAB2	NAB2_2_gene	KIF5A	-0.224	0.159	0.159	0.849
rs186132169	NGEF	NGEF_3_gene	EIF4E2	0.181	0.165	0.157	0.849
rs324015	STAT6	STAT6_1_gene	DTX3	-0.106	0.159	0.159	0.849
rs7148456	BAG5	BAG5_2_gene	MARK3	-0.0739	0.162	0.175	0.866
rs7148456	BAG5	BAG5_3_gene	TRAF3	-0.129	0.157	0.169	0.866
rs520843	GALNT10	GALNT10_3_gene	SAP30L	-0.0649	0.17	0.174	0.866
rs3861678	LINC00637	LINC00637_3_gene	BAG5	-0.076	0.175	0.175	0.866
rs324017	NAB2	NAB2_2_gene	MARCH9	0.118	0.17	0.17	0.866
rs186132169	NGEF	NGEF_1_gene	USP40	-0.142	0.177	0.173	0.866
rs10933	PBRM1	PBRM1_1_gene	WDR82	0.146	0.174	0.169	0.866
rs10933	PBRM1	PBRM1_3_gene	SFMBT1	-0.15	0.172	0.165	0.866
rs6071578	PPP1R16B	PPP1R16B_1_gene	RPRD1B	-0.0747	0.155	0.165	0.866
rs301791	RERE	RERE_1_gene	ENO1	0.0859	0.173	0.169	0.866
rs324015	STAT6	STAT6_2_gene	BAZ2A	-0.0829	0.166	0.174	0.866
rs324015	STAT6	STAT6_3_gene	MYL6	0.122	0.176	0.17	0.866
rs2027349	VPS45	VPS45_1_gene	CA14	0.356	0.173	0.171	0.866
rs2027349	VPS45	VPS45_3_gene	BOLA1	0.13	0.163	0.17	0.866
rs324017	NAB2	NAB2_1_gene	R3HDM2	-0.093	0.188	0.177	0.872
rs7170068	CHRNA3	CHRNA3_1_gene	PSMA4	-0.126	0.196	0.183	0.876
rs3861678	LINC00637	LINC00637_3_gene	ZFYVE21	0.065	0.179	0.179	0.876
rs324017	NAB2	NAB2_1_gene	ATP23	-0.0735	0.193	0.181	0.876
rs324017	NAB2	NAB2_2_gene	ESYT1	0.0938	0.182	0.183	0.876
rs10933	PBRM1	PBRM1_1_gene	PCBP4	-0.302	0.187	0.183	0.876
rs7170068	CHRNA3	CHRNA3_2_gene	CTSH	0.131	0.185	0.189	0.894
rs12716973	KCTD13	KCTD13_2_gene	TAOK2	0.104	0.19	0.189	0.894
rs301791	RERE	RERE_1_gene	PARK7	0.0465	0.194	0.19	0.894
rs2027349	VPS45	VPS45_3_gene	APH1A	0.139	0.182	0.191	0.894
rs17200916	LOC105376975	LOC105376975_3_gene	SATB1	0.143	0.194	0.195	0.903
rs4151680	PCDHA123	PCDHA123_1_gene	ANKHD1	-0.0671	0.201	0.194	0.903
rs3861678	LINC00637	LINC00637_2_gene	TRMT61A	-0.0743	0.206	0.198	0.909
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ZSCAN2	-0.144	0.192	0.197	0.909
rs12716973	KCTD13	KCTD13_3_gene	ZNF688	-0.141	0.201	0.199	0.909
rs324017	NAB2	NAB2_2_gene	DTX3	-0.109	0.199	0.2	0.909
rs7148456	BAG5	BAG5_1_gene	BAG5	-0.0788	0.258	0.251	0.92
rs7148456	BAG5	BAG5_2_gene	PPP1R13B	-0.0763	0.235	0.249	0.92
rs12895055	BCL11B	BCL11B_3_gene	YY1	-0.112	0.226	0.231	0.92
rs7170068	CHRNA3	CHRNA3_1_gene	CHRNA3	-0.451	0.272	0.257	0.92
rs7170068	CHRNA3	CHRNA3_1_gene	IREB2	0.11	0.299	0.284	0.92
rs520843	GALNT10	GALNT10_3_gene	CNOT8	-0.0586	0.234	0.24	0.92
rs520843	GALNT10	GALNT10_3_gene	GALNT10	0.0687	0.262	0.268	0.92
rs520843	GALNT10	GALNT10_3_gene	LARP1	0.0543	0.272	0.277	0.92
rs12716973	KCTD13	KCTD13_1_gene	KCTD13	-0.0944	0.219	0.221	0.92
rs12716973	KCTD13	KCTD13_1_gene	PPP4C	0.0598	0.27	0.273	0.92
rs12716973	KCTD13	KCTD13_1_gene	QPRT	0.117	0.271	0.274	0.92
rs12716973	KCTD13	KCTD13_1_gene	YPEL3	-0.1	0.279	0.282	0.92
rs12716973	KCTD13	KCTD13_1_gene	ZNF771	0.0812	0.205	0.206	0.92
rs12716973	KCTD13	KCTD13_2_gene	BCL7C	0.101	0.284	0.282	0.92
rs12716973	KCTD13	KCTD13_2_gene	CCDC189	-0.102	0.265	0.263	0.92
rs12716973	KCTD13	KCTD13_2_gene	MAZ	-0.107	0.216	0.215	0.92
rs12716973	KCTD13	KCTD13_2_gene	ZNF785	0.12	0.223	0.222	0.92
rs12716973	KCTD13	KCTD13_3_gene	CD2BP2	0.131	0.218	0.216	0.92
rs12716973	KCTD13	KCTD13_3_gene	MAPK3	0.149	0.221	0.22	0.92
rs12716973	KCTD13	KCTD13_3_gene	SEPT1	-0.122	0.281	0.279	0.92
rs12716973	KCTD13	KCTD13_3_gene	YPEL3	0.184	0.249	0.247	0.92
rs12716973	KCTD13	KCTD13_3_gene	ZNF771	0.126	0.253	0.251	0.92
rs2192932	KMT2E	KMT2E_2_gene	ORC5	-0.0805	0.247	0.246	0.92
rs2192932	KMT2E	KMT2E_3_gene	RINT1	-0.0747	0.282	0.28	0.92
rs3861678	LINC00637	LINC00637_2_gene	INF2	0.0623	0.293	0.285	0.92
rs3861678	LINC00637	LINC00637_2_gene	PPP1R13B	0.0768	0.294	0.286	0.92
rs3861678	LINC00637	LINC00637_2_gene	ZFYVE21	0.0679	0.24	0.232	0.92
rs3861678	LINC00637	LINC00637_3_gene	PPP1R13B	-0.0683	0.266	0.265	0.92
rs324017	NAB2	NAB2_1_gene	COQ10A	-0.0872	0.235	0.224	0.92
rs324017	NAB2	NAB2_1_gene	METTL1	-0.0711	0.244	0.233	0.92
rs324017	NAB2	NAB2_1_gene	PA2G4	-0.076	0.284	0.273	0.92
rs324017	NAB2	NAB2_1_gene	PRIM1	-0.0946	0.229	0.218	0.92
rs324017	NAB2	NAB2_1_gene	RNF41	0.0713	0.236	0.224	0.92
rs324017	NAB2	NAB2_2_gene	METTL1	0.0886	0.224	0.225	0.92
rs324017	NAB2	NAB2_2_gene	NACA	-0.0667	0.23	0.232	0.92
rs324017	NAB2	NAB2_3_gene	MYL6	-0.13	0.238	0.24	0.92
rs324017	NAB2	NAB2_3_gene	NAB2	-0.0975	0.256	0.258	0.92
rs324017	NAB2	NAB2_3_gene	NACA	-0.0649	0.241	0.243	0.92
rs324017	NAB2	NAB2_3_gene	R3HDM2	0.107	0.203	0.205	0.92
rs324017	NAB2	NAB2_3_gene	RPL41	-0.111	0.257	0.26	0.92
rs186132169	NGEF	NGEF_1_gene	DGKD	-0.141	0.244	0.24	0.92
rs186132169	NGEF	NGEF_1_gene	TIGD1	-0.125	0.274	0.27	0.92
rs186132169	NGEF	NGEF_3_gene	ATG16L1	-0.154	0.24	0.231	0.92
rs186132169	NGEF	NGEF_3_gene	DGKD	-0.157	0.286	0.276	0.92
rs10933	PBRM1	PBRM1_1_gene	BAP1	-0.109	0.271	0.267	0.92
rs10933	PBRM1	PBRM1_2_gene	GNL3	-0.129	0.243	0.242	0.92
rs10933	PBRM1	PBRM1_3_gene	ALAS1	-0.117	0.256	0.248	0.92
rs10933	PBRM1	PBRM1_3_gene	NT5DC2	-0.143	0.292	0.283	0.92
rs10933	PBRM1	PBRM1_3_gene	TEX264	-0.117	0.252	0.244	0.92
rs4151680	PCDHA123	PCDHA123_1_gene	DIAPH1	-0.0592	0.293	0.285	0.92
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB10	0.0947	0.261	0.253	0.92
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB5	-0.0754	0.251	0.243	0.92
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHGB6	0.0805	0.225	0.219	0.92
rs4151680	PCDHA123	PCDHA123_2_gene	SRA1	-0.0507	0.29	0.282	0.92
rs4151680	PCDHA123	PCDHA123_3_gene	CYSTM1	0.0948	0.211	0.206	0.92
rs4151680	PCDHA123	PCDHA123_3_gene	NDUFA2	-0.0416	0.26	0.255	0.92
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB14	0.0662	0.222	0.217	0.92
rs4151680	PCDHA123	PCDHA123_3_gene	PFDN1	0.0417	0.283	0.278	0.92
rs6071578	PPP1R16B	PPP1R16B_2_gene	ACTR5	0.0647	0.281	0.279	0.92
rs6071578	PPP1R16B	PPP1R16B_2_gene	RALGAPB	0.0645	0.276	0.273	0.92
rs6071578	PPP1R16B	PPP1R16B_2_gene	TTI1	-0.0642	0.256	0.254	0.92
rs301791	RERE	RERE_3_gene	RERE	-0.0938	0.244	0.248	0.92
rs324015	STAT6	STAT6_1_gene	ANKRD52	0.0667	0.278	0.278	0.92
rs324015	STAT6	STAT6_1_gene	B4GALNT1	-0.104	0.249	0.25	0.92
rs324015	STAT6	STAT6_1_gene	SMARCC2	-0.0966	0.213	0.214	0.92
rs324015	STAT6	STAT6_1_gene	ZC3H10	-0.0731	0.284	0.285	0.92
rs324015	STAT6	STAT6_2_gene	DCTN2	-0.0666	0.222	0.232	0.92
rs324015	STAT6	STAT6_2_gene	KIF5A	-0.157	0.195	0.204	0.92
rs324015	STAT6	STAT6_2_gene	MARS	-0.0641	0.264	0.275	0.92
rs324015	STAT6	STAT6_2_gene	MYL6B	-0.0776	0.204	0.214	0.92
rs324015	STAT6	STAT6_2_gene	NAB2	0.0805	0.221	0.231	0.92
rs324015	STAT6	STAT6_3_gene	DCTN2	-0.0632	0.276	0.269	0.92
rs324015	STAT6	STAT6_3_gene	MBD6	-0.0639	0.288	0.281	0.92
rs324015	STAT6	STAT6_3_gene	NAB2	0.0784	0.263	0.256	0.92
rs9882911	TRANK1	TRANK1_2_gene	MLH1	0.0911	0.264	0.26	0.92
rs9882911	TRANK1	TRANK1_3_gene	LRRFIP2	0.0485	0.251	0.251	0.92
rs2027349	VPS45	VPS45_1_gene	C1orf56	-0.113	0.261	0.26	0.92
rs2027349	VPS45	VPS45_1_gene	MLLT11	-0.296	0.28	0.279	0.92
rs2027349	VPS45	VPS45_2_gene	CERS2	0.0502	0.224	0.216	0.92
rs2027349	VPS45	VPS45_2_gene	MCL1	0.0524	0.293	0.285	0.92
rs2027349	VPS45	VPS45_2_gene	TARS2	-0.0473	0.245	0.238	0.92
rs2027349	VPS45	VPS45_3_gene	CERS2	0.11	0.225	0.233	0.92
rs2027349	VPS45	VPS45_3_gene	ECM1	-0.422	0.246	0.253	0.92
rs2027349	VPS45	VPS45_3_gene	MRPS21	-0.0924	0.24	0.248	0.92
rs301791	RERE	RERE_1_gene	VAMP3	0.0584	0.291	0.288	0.922
rs7148456	BAG5	BAG5_2_gene	APOPT1	0.054	0.282	0.297	0.925
rs7170068	CHRNA3	CHRNA3_2_gene	TMED3	-0.109	0.295	0.299	0.925
rs520843	GALNT10	GALNT10_2_gene	FAM114A2	0.0633	0.311	0.301	0.925
rs12716973	KCTD13	KCTD13_3_gene	KIF22	-0.229	0.296	0.294	0.925
rs12716973	KCTD13	KCTD13_3_gene	TMEM219	-0.11	0.301	0.299	0.925
rs2192932	KMT2E	KMT2E_2_gene	KMT2E	-0.0977	0.301	0.3	0.925
rs2192932	KMT2E	KMT2E_3_gene	ATXN7L1	-0.0741	0.302	0.301	0.925
rs324017	NAB2	NAB2_3_gene	B4GALNT1	-0.106	0.3	0.303	0.925
rs186132169	NGEF	NGEF_1_gene	EIF4E2	0.111	0.305	0.301	0.925
rs6071578	PPP1R16B	PPP1R16B_3_gene	VSTM2L	-0.159	0.299	0.295	0.925
rs324015	STAT6	STAT6_3_gene	PA2G4	-0.0699	0.31	0.303	0.925
rs9882911	TRANK1	TRANK1_3_gene	GOLGA4	0.0531	0.294	0.294	0.925
rs2027349	VPS45	VPS45_1_gene	PLEKHO1	0.102	0.297	0.296	0.925
rs2027349	VPS45	VPS45_1_gene	RPRD2	0.104	0.304	0.303	0.925
rs2027349	VPS45	VPS45_3_gene	TARS2	-0.0939	0.292	0.299	0.925
rs7170068	CHRNA3	CHRNA3_2_gene	CHRNA5	0.104	0.302	0.306	0.931
rs7148456	BAG5	BAG5_1_gene	KLC1	-0.0699	0.515	0.509	0.932
rs7148456	BAG5	BAG5_1_gene	RCOR1	-0.0526	0.42	0.413	0.932
rs7148456	BAG5	BAG5_1_gene	TRAF3	0.0451	0.507	0.502	0.932
rs7148456	BAG5	BAG5_2_gene	TRMT61A	-0.04	0.438	0.452	0.932
rs7148456	BAG5	BAG5_2_gene	ZFYVE21	0.0468	0.356	0.371	0.932
rs7148456	BAG5	BAG5_3_gene	APOPT1	0.0545	0.495	0.508	0.932
rs7148456	BAG5	BAG5_3_gene	EIF5	0.0762	0.488	0.502	0.932
rs7148456	BAG5	BAG5_3_gene	KLC1	-0.118	0.409	0.424	0.932
rs12895055	BCL11B	BCL11B_1_gene	EML1	0.0678	0.415	0.423	0.932
rs12895055	BCL11B	BCL11B_3_gene	CCDC85C	-0.082	0.382	0.388	0.932
rs12895055	BCL11B	BCL11B_3_gene	CYP46A1	0.122	0.307	0.312	0.932
rs12895055	BCL11B	BCL11B_3_gene	EVL	0.0763	0.544	0.548	0.932
rs7170068	CHRNA3	CHRNA3_1_gene	ADAMTS7	-0.0836	0.451	0.436	0.932
rs7170068	CHRNA3	CHRNA3_1_gene	CHRNA5	0.116	0.379	0.364	0.932
rs7170068	CHRNA3	CHRNA3_1_gene	CRABP1	-1.42	0.553	0.541	0.932
rs7170068	CHRNA3	CHRNA3_1_gene	TMED3	0.125	0.359	0.343	0.932
rs7170068	CHRNA3	CHRNA3_2_gene	CRABP1	1.3	0.476	0.48	0.932
rs7170068	CHRNA3	CHRNA3_2_gene	IREB2	0.0779	0.333	0.337	0.932
rs7170068	CHRNA3	CHRNA3_2_gene	WDR61	0.0532	0.459	0.462	0.932
rs7170068	CHRNA3	CHRNA3_3_gene	CHRNA5	0.0822	0.479	0.474	0.932
rs7170068	CHRNA3	CHRNA3_3_gene	PSMA4	0.0705	0.412	0.406	0.932
rs7170068	CHRNA3	CHRNA3_3_gene	WDR61	-0.0505	0.542	0.539	0.932
rs9661794	DPYD	DPYD_1_gene	SNX7	0.0443	0.493	0.497	0.932
rs9661794	DPYD	DPYD_2_gene	SNX7	-0.0351	0.457	0.463	0.932
rs520843	GALNT10	GALNT10_1_gene	CNOT8	-0.0327	0.548	0.545	0.932
rs520843	GALNT10	GALNT10_1_gene	MFAP3	-0.0543	0.322	0.319	0.932
rs520843	GALNT10	GALNT10_1_gene	MRPL22	0.0329	0.525	0.522	0.932
rs520843	GALNT10	GALNT10_2_gene	GALNT10	-0.05	0.521	0.513	0.932
rs520843	GALNT10	GALNT10_2_gene	GEMIN5	0.0521	0.395	0.385	0.932
rs520843	GALNT10	GALNT10_2_gene	MFAP3	0.0477	0.45	0.442	0.932
rs520843	GALNT10	GALNT10_2_gene	MRPL22	-0.0407	0.494	0.486	0.932
rs520843	GALNT10	GALNT10_2_gene	SAP30L	0.0534	0.374	0.364	0.932
rs520843	GALNT10	GALNT10_3_gene	FAM114A2	0.0368	0.455	0.461	0.932
rs520843	GALNT10	GALNT10_3_gene	MRPL22	0.0458	0.328	0.334	0.932
rs12716973	KCTD13	KCTD13_1_gene	CCDC189	-0.0544	0.441	0.445	0.932
rs12716973	KCTD13	KCTD13_1_gene	MAPK3	-0.0524	0.461	0.464	0.932
rs12716973	KCTD13	KCTD13_1_gene	PRR14	0.0506	0.428	0.431	0.932
rs12716973	KCTD13	KCTD13_1_gene	RNF40	0.0434	0.49	0.493	0.932
rs12716973	KCTD13	KCTD13_1_gene	SEZ6L2	-0.113	0.43	0.434	0.932
rs12716973	KCTD13	KCTD13_1_gene	TBC1D10B	-0.0433	0.506	0.509	0.932
rs12716973	KCTD13	KCTD13_1_gene	TMEM219	0.0515	0.405	0.409	0.932
rs12716973	KCTD13	KCTD13_1_gene	ZNF689	0.0691	0.314	0.317	0.932
rs12716973	KCTD13	KCTD13_1_gene	ZNF764	-0.0408	0.543	0.546	0.932
rs12716973	KCTD13	KCTD13_2_gene	CD2BP2	0.0656	0.413	0.412	0.932
rs12716973	KCTD13	KCTD13_2_gene	CORO1A	0.0907	0.494	0.493	0.932
rs12716973	KCTD13	KCTD13_2_gene	FBRS	-0.0855	0.315	0.313	0.932
rs12716973	KCTD13	KCTD13_2_gene	HIRIP3	-0.0931	0.36	0.358	0.932
rs12716973	KCTD13	KCTD13_2_gene	INO80E	0.0759	0.333	0.331	0.932
rs12716973	KCTD13	KCTD13_2_gene	PRR14	-0.0518	0.53	0.529	0.932
rs12716973	KCTD13	KCTD13_2_gene	RNF40	0.0681	0.402	0.401	0.932
rs12716973	KCTD13	KCTD13_2_gene	ZNF629	-0.084	0.329	0.327	0.932
rs12716973	KCTD13	KCTD13_2_gene	ZNF688	0.0536	0.518	0.517	0.932
rs12716973	KCTD13	KCTD13_2_gene	ZNF764	-0.0866	0.319	0.317	0.932
rs12716973	KCTD13	KCTD13_2_gene	ZNF771	-0.0492	0.552	0.551	0.932
rs12716973	KCTD13	KCTD13_3_gene	DCTPP1	0.0778	0.527	0.526	0.932
rs12716973	KCTD13	KCTD13_3_gene	FAM57B	-0.233	0.345	0.344	0.932
rs12716973	KCTD13	KCTD13_3_gene	PRR14	0.0879	0.423	0.422	0.932
rs12716973	KCTD13	KCTD13_3_gene	SEPHS2	-0.129	0.389	0.388	0.932
rs12716973	KCTD13	KCTD13_3_gene	TAOK2	-0.0665	0.527	0.527	0.932
rs12716973	KCTD13	KCTD13_3_gene	ZNF48	0.0754	0.536	0.535	0.932
rs2192932	KMT2E	KMT2E_1_gene	SRPK2	0.146	0.344	0.341	0.932
rs2192932	KMT2E	KMT2E_2_gene	ATXN7L1	0.0532	0.462	0.462	0.932
rs2192932	KMT2E	KMT2E_2_gene	RINT1	-0.0561	0.423	0.422	0.932
rs2192932	KMT2E	KMT2E_3_gene	ORC5	-0.0495	0.473	0.471	0.932
rs2192932	KMT2E	KMT2E_3_gene	PUS7	-0.0604	0.385	0.383	0.932
rs3861678	LINC00637	LINC00637_1_gene	ADSSL1	0.0499	0.427	0.427	0.932
rs3861678	LINC00637	LINC00637_1_gene	AKT1	-0.0378	0.473	0.473	0.932
rs3861678	LINC00637	LINC00637_1_gene	APOPT1	-0.0409	0.439	0.439	0.932
rs3861678	LINC00637	LINC00637_1_gene	INF2	0.0362	0.509	0.509	0.932
rs3861678	LINC00637	LINC00637_1_gene	KLC1	0.0641	0.5	0.501	0.932
rs3861678	LINC00637	LINC00637_2_gene	ADSSL1	0.0515	0.45	0.442	0.932
rs3861678	LINC00637	LINC00637_2_gene	CDC42BPB	0.0643	0.331	0.323	0.932
rs3861678	LINC00637	LINC00637_2_gene	EIF5	-0.0694	0.378	0.371	0.932
rs3861678	LINC00637	LINC00637_3_gene	CKB	0.0682	0.551	0.551	0.932
rs3861678	LINC00637	LINC00637_3_gene	KLC1	0.0515	0.551	0.551	0.932
rs3861678	LINC00637	LINC00637_3_gene	MARK3	-0.0355	0.482	0.481	0.932
rs7936858	LOC100507431	LOC100507431_1_gene	APLP2	0.115	0.376	0.371	0.932
rs7936858	LOC100507431	LOC100507431_2_gene	APLP2	-0.0724	0.489	0.482	0.932
rs7936858	LOC100507431	LOC100507431_2_gene	NFRKB	-0.0672	0.354	0.345	0.932
rs7936858	LOC100507431	LOC100507431_2_gene	SNX19	0.0538	0.459	0.451	0.932
rs7936858	LOC100507431	LOC100507431_3_gene	SNX19	-0.039	0.442	0.445	0.932
rs17200916	LOC105376975	LOC105376975_2_gene	PLCL2	-0.0528	0.408	0.411	0.932
rs17200916	LOC105376975	LOC105376975_3_gene	TBC1D5	-0.0729	0.368	0.369	0.932
rs1198588	miR137	miR137_1_gene	SNX7	-0.0387	0.521	0.522	0.932
rs324017	NAB2	NAB2_1_gene	ANKRD52	0.0531	0.359	0.348	0.932
rs324017	NAB2	NAB2_1_gene	ARHGEF25	0.0601	0.344	0.333	0.932
rs324017	NAB2	NAB2_1_gene	B4GALNT1	0.0846	0.323	0.312	0.932
rs324017	NAB2	NAB2_1_gene	BAZ2A	0.0578	0.378	0.368	0.932
rs324017	NAB2	NAB2_1_gene	CNPY2	-0.0378	0.513	0.504	0.932
rs324017	NAB2	NAB2_1_gene	CS	0.042	0.464	0.453	0.932
rs324017	NAB2	NAB2_1_gene	DCTN2	0.041	0.494	0.484	0.932
rs324017	NAB2	NAB2_1_gene	DTX3	-0.0495	0.485	0.475	0.932
rs324017	NAB2	NAB2_1_gene	LRP1	0.0401	0.558	0.55	0.932
rs324017	NAB2	NAB2_1_gene	MARCH9	0.0692	0.337	0.326	0.932
rs324017	NAB2	NAB2_1_gene	MARS	-0.042	0.505	0.496	0.932
rs324017	NAB2	NAB2_1_gene	MYL6	0.0616	0.507	0.498	0.932
rs324017	NAB2	NAB2_1_gene	NAB2	-0.0418	0.563	0.554	0.932
rs324017	NAB2	NAB2_1_gene	SMARCC2	0.0562	0.443	0.433	0.932
rs324017	NAB2	NAB2_1_gene	TSFM	-0.0511	0.345	0.335	0.932
rs324017	NAB2	NAB2_2_gene	COQ10A	-0.0701	0.424	0.429	0.932
rs324017	NAB2	NAB2_2_gene	CTDSP2	0.0565	0.469	0.474	0.932
rs324017	NAB2	NAB2_2_gene	DCTN2	-0.0675	0.345	0.348	0.932
rs324017	NAB2	NAB2_2_gene	NAB2	0.0638	0.458	0.463	0.932
rs324017	NAB2	NAB2_2_gene	NABP2	-0.0667	0.341	0.345	0.932
rs324017	NAB2	NAB2_2_gene	PIP4K2C	-0.0517	0.493	0.497	0.932
rs324017	NAB2	NAB2_2_gene	PRIM1	0.0661	0.481	0.486	0.932
rs324017	NAB2	NAB2_2_gene	PTGES3	0.052	0.489	0.493	0.932
rs324017	NAB2	NAB2_2_gene	R3HDM2	-0.0705	0.403	0.407	0.932
rs324017	NAB2	NAB2_2_gene	RPL41	0.0861	0.379	0.383	0.932
rs324017	NAB2	NAB2_2_gene	SMARCC2	-0.0877	0.315	0.319	0.932
rs324017	NAB2	NAB2_2_gene	SPRYD4	-0.0542	0.434	0.439	0.932
rs324017	NAB2	NAB2_2_gene	TSFM	-0.0619	0.338	0.342	0.932
rs324017	NAB2	NAB2_2_gene	TSPAN31	-0.0467	0.507	0.511	0.932
rs324017	NAB2	NAB2_2_gene	ZC3H10	0.0621	0.419	0.423	0.932
rs324017	NAB2	NAB2_3_gene	ARHGEF25	0.0647	0.391	0.394	0.932
rs324017	NAB2	NAB2_3_gene	ATP23	0.062	0.355	0.359	0.932
rs324017	NAB2	NAB2_3_gene	CDK4	-0.101	0.416	0.419	0.932
rs324017	NAB2	NAB2_3_gene	CNPY2	0.0448	0.514	0.515	0.932
rs324017	NAB2	NAB2_3_gene	COQ10A	0.0593	0.497	0.498	0.932
rs324017	NAB2	NAB2_3_gene	CS	-0.0472	0.489	0.49	0.932
rs324017	NAB2	NAB2_3_gene	CTDSP2	-0.0465	0.55	0.552	0.932
rs324017	NAB2	NAB2_3_gene	DDIT3	0.15	0.321	0.324	0.932
rs324017	NAB2	NAB2_3_gene	ESYT1	-0.0567	0.419	0.422	0.932
rs324017	NAB2	NAB2_3_gene	MARCH9	0.0725	0.397	0.4	0.932
rs324017	NAB2	NAB2_3_gene	NABP2	-0.0459	0.511	0.512	0.932
rs324017	NAB2	NAB2_3_gene	NXPH4	0.175	0.462	0.464	0.932
rs324017	NAB2	NAB2_3_gene	OS9	-0.0578	0.394	0.397	0.932
rs324017	NAB2	NAB2_3_gene	PIP4K2C	-0.0709	0.345	0.349	0.932
rs324017	NAB2	NAB2_3_gene	PTGES3	0.0448	0.55	0.551	0.932
rs324017	NAB2	NAB2_3_gene	RNF41	-0.0604	0.399	0.402	0.932
rs324017	NAB2	NAB2_3_gene	SPRYD4	0.0467	0.499	0.5	0.932
rs324017	NAB2	NAB2_3_gene	TIMELESS	-0.0842	0.335	0.338	0.932
rs324017	NAB2	NAB2_3_gene	TSFM	0.0465	0.471	0.472	0.932
rs324017	NAB2	NAB2_3_gene	ZC3H10	0.0637	0.406	0.409	0.932
rs186132169	NGEF	NGEF_3_gene	ECEL1	0.567	0.386	0.377	0.932
rs186132169	NGEF	NGEF_3_gene	TIGD1	-0.095	0.491	0.482	0.932
rs186132169	NGEF	NGEF_3_gene	USP40	-0.106	0.406	0.396	0.932
rs10933	PBRM1	PBRM1_1_gene	ABHD14A	-0.168	0.326	0.322	0.932
rs10933	PBRM1	PBRM1_1_gene	CACNA1D	-0.0923	0.53	0.528	0.932
rs10933	PBRM1	PBRM1_1_gene	NEK4	-0.0697	0.512	0.511	0.932
rs10933	PBRM1	PBRM1_1_gene	NISCH	0.0822	0.461	0.459	0.932
rs10933	PBRM1	PBRM1_1_gene	POC1A	0.126	0.413	0.41	0.932
rs10933	PBRM1	PBRM1_1_gene	SFMBT1	-0.073	0.505	0.504	0.932
rs10933	PBRM1	PBRM1_1_gene	SPCS1	0.0725	0.422	0.419	0.932
rs10933	PBRM1	PBRM1_2_gene	ABHD14A	-0.122	0.453	0.453	0.932
rs10933	PBRM1	PBRM1_2_gene	ALAS1	-0.0579	0.553	0.553	0.932
rs10933	PBRM1	PBRM1_2_gene	BAP1	0.0631	0.505	0.505	0.932
rs10933	PBRM1	PBRM1_2_gene	NT5DC2	0.0953	0.459	0.458	0.932
rs10933	PBRM1	PBRM1_2_gene	PHF7	0.0644	0.529	0.529	0.932
rs10933	PBRM1	PBRM1_2_gene	POC1A	0.0916	0.531	0.531	0.932
rs10933	PBRM1	PBRM1_2_gene	RRP9	-0.0844	0.414	0.413	0.932
rs10933	PBRM1	PBRM1_2_gene	SMIM4	0.0979	0.325	0.324	0.932
rs10933	PBRM1	PBRM1_2_gene	SPCS1	0.0733	0.394	0.394	0.932
rs10933	PBRM1	PBRM1_3_gene	ABHD14B	0.0839	0.447	0.441	0.932
rs10933	PBRM1	PBRM1_3_gene	BAP1	0.0671	0.502	0.497	0.932
rs10933	PBRM1	PBRM1_3_gene	PCBP4	0.161	0.485	0.48	0.932
rs4151680	PCDHA123	PCDHA123_1_gene	HARS2	0.0389	0.456	0.448	0.932
rs4151680	PCDHA123	PCDHA123_1_gene	HBEGF	0.231	0.331	0.324	0.932
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA12	0.0469	0.526	0.518	0.932
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB16	-0.0631	0.406	0.399	0.932
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHGA7	0.0614	0.513	0.506	0.932
rs4151680	PCDHA123	PCDHA123_1_gene	SRA1	0.0534	0.355	0.348	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	APBB3	0.0393	0.452	0.444	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	DIAPH1	0.0323	0.49	0.482	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA10	0.0561	0.322	0.315	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA12	0.0395	0.52	0.512	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB14	-0.0352	0.553	0.547	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB16	-0.0511	0.417	0.409	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHGA10	0.0444	0.445	0.437	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	PFDN1	0.0315	0.458	0.45	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	TAF7	-0.0502	0.377	0.369	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	ZMAT2	-0.0337	0.441	0.433	0.932
rs4151680	PCDHA123	PCDHA123_3_gene	DIAPH1	-0.0282	0.509	0.505	0.932
rs4151680	PCDHA123	PCDHA123_3_gene	HARS	0.0282	0.502	0.497	0.932
rs4151680	PCDHA123	PCDHA123_3_gene	IK	-0.03	0.559	0.554	0.932
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB10	0.0375	0.557	0.553	0.932
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHGA10	-0.0511	0.336	0.331	0.932
rs4151680	PCDHA123	PCDHA123_3_gene	SLC35A4	-0.0265	0.494	0.49	0.932
rs4151680	PCDHA123	PCDHA123_3_gene	ZMAT2	0.0239	0.549	0.545	0.932
rs6071578	PPP1R16B	PPP1R16B_1_gene	ACTR5	-0.0365	0.508	0.52	0.932
rs6071578	PPP1R16B	PPP1R16B_1_gene	RALGAPB	0.0449	0.409	0.422	0.932
rs6071578	PPP1R16B	PPP1R16B_1_gene	TTI1	-0.0336	0.518	0.53	0.932
rs6071578	PPP1R16B	PPP1R16B_3_gene	SNHG11	-0.0425	0.539	0.537	0.932
rs6071578	PPP1R16B	PPP1R16B_3_gene	TTI1	-0.0585	0.328	0.324	0.932
rs301791	RERE	RERE_2_gene	PARK7	0.0434	0.357	0.354	0.932
rs301791	RERE	RERE_2_gene	SLC45A1	-0.0638	0.413	0.411	0.932
rs301791	RERE	RERE_3_gene	CAMTA1	-0.0418	0.526	0.529	0.932
rs301791	RERE	RERE_3_gene	SLC45A1	-0.0692	0.426	0.43	0.932
rs324015	STAT6	STAT6_1_gene	ARHGEF25	0.0659	0.327	0.328	0.932
rs324015	STAT6	STAT6_1_gene	CDK4	0.0791	0.476	0.476	0.932
rs324015	STAT6	STAT6_1_gene	CNPY2	-0.037	0.546	0.546	0.932
rs324015	STAT6	STAT6_1_gene	CS	0.0549	0.366	0.366	0.932
rs324015	STAT6	STAT6_1_gene	CTDSP2	0.0638	0.358	0.358	0.932
rs324015	STAT6	STAT6_1_gene	MARS	0.0505	0.45	0.45	0.932
rs324015	STAT6	STAT6_1_gene	METTL1	0.0602	0.352	0.352	0.932
rs324015	STAT6	STAT6_1_gene	R3HDM2	0.0496	0.508	0.509	0.932
rs324015	STAT6	STAT6_1_gene	SPRYD4	-0.045	0.466	0.466	0.932
rs324015	STAT6	STAT6_1_gene	STAT2	0.0603	0.337	0.337	0.932
rs324015	STAT6	STAT6_1_gene	TIMELESS	0.0587	0.451	0.451	0.932
rs324015	STAT6	STAT6_2_gene	ANKRD52	-0.0402	0.447	0.457	0.932
rs324015	STAT6	STAT6_2_gene	CDK4	0.0631	0.508	0.518	0.932
rs324015	STAT6	STAT6_2_gene	CTDSP2	0.0522	0.381	0.392	0.932
rs324015	STAT6	STAT6_2_gene	DDIT3	0.12	0.3	0.311	0.932
rs324015	STAT6	STAT6_2_gene	NABP2	-0.0347	0.517	0.527	0.932
rs324015	STAT6	STAT6_2_gene	NACA	0.0393	0.354	0.366	0.932
rs324015	STAT6	STAT6_2_gene	RNF41	0.0358	0.513	0.523	0.932
rs324015	STAT6	STAT6_3_gene	ANKRD52	0.0418	0.457	0.452	0.932
rs324015	STAT6	STAT6_3_gene	ATP23	0.048	0.381	0.374	0.932
rs324015	STAT6	STAT6_3_gene	B4GALNT1	0.064	0.441	0.435	0.932
rs324015	STAT6	STAT6_3_gene	CNPY2	0.0448	0.424	0.418	0.932
rs324015	STAT6	STAT6_3_gene	DDIT3	-0.0784	0.523	0.519	0.932
rs324015	STAT6	STAT6_3_gene	KIF5A	0.0756	0.559	0.554	0.932
rs324015	STAT6	STAT6_3_gene	MARCH9	0.0496	0.477	0.471	0.932
rs324015	STAT6	STAT6_3_gene	MYL6B	0.0445	0.494	0.488	0.932
rs324015	STAT6	STAT6_3_gene	NABP2	0.0385	0.499	0.493	0.932
rs324015	STAT6	STAT6_3_gene	NACA	-0.0433	0.338	0.331	0.932
rs324015	STAT6	STAT6_3_gene	NXPH4	0.131	0.499	0.493	0.932
rs324015	STAT6	STAT6_3_gene	PRIM1	-0.0663	0.386	0.379	0.932
rs324015	STAT6	STAT6_3_gene	R3HDM2	-0.0509	0.459	0.453	0.932
rs324015	STAT6	STAT6_3_gene	SPRYD4	-0.0507	0.369	0.362	0.932
rs324015	STAT6	STAT6_3_gene	STAT2	-0.0443	0.441	0.435	0.932
rs9882911	TRANK1	TRANK1_2_gene	EPM2AIP1	0.0829	0.378	0.376	0.932
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	NMB	0.105	0.39	0.394	0.932
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	SH3GL3	-0.0993	0.46	0.465	0.932
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	AKAP13	-0.103	0.459	0.467	0.932
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	SH3GL3	0.0858	0.526	0.533	0.932
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	AKAP13	0.0934	0.415	0.398	0.932
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	SH3GL3	-0.0698	0.532	0.517	0.932
rs2027349	VPS45	VPS45_1_gene	APH1A	0.0796	0.448	0.447	0.932
rs2027349	VPS45	VPS45_1_gene	CERS2	0.0639	0.481	0.48	0.932
rs2027349	VPS45	VPS45_1_gene	ECM1	0.329	0.367	0.366	0.932
rs2027349	VPS45	VPS45_1_gene	ENSA	-0.0704	0.399	0.397	0.932
rs2027349	VPS45	VPS45_1_gene	OTUD7B	-0.0821	0.405	0.403	0.932
rs2027349	VPS45	VPS45_1_gene	PRPF3	-0.0855	0.404	0.402	0.932
rs2027349	VPS45	VPS45_1_gene	SF3B4	-0.0662	0.473	0.472	0.932
rs2027349	VPS45	VPS45_1_gene	SV2A	-0.153	0.431	0.43	0.932
rs2027349	VPS45	VPS45_2_gene	CA14	0.0874	0.462	0.454	0.932
rs2027349	VPS45	VPS45_2_gene	GOLPH3L	-0.0239	0.553	0.546	0.932
rs2027349	VPS45	VPS45_2_gene	MLLT11	-0.0945	0.449	0.441	0.932
rs2027349	VPS45	VPS45_2_gene	OTUD7B	-0.0431	0.337	0.329	0.932
rs2027349	VPS45	VPS45_2_gene	SV2A	-0.0773	0.383	0.375	0.932
rs2027349	VPS45	VPS45_3_gene	ARNT	-0.0613	0.495	0.503	0.932
rs2027349	VPS45	VPS45_3_gene	CDC42SE1	-0.0682	0.458	0.466	0.932
rs2027349	VPS45	VPS45_3_gene	MCL1	0.0671	0.538	0.545	0.932
rs2027349	VPS45	VPS45_3_gene	PRPF3	0.0717	0.482	0.49	0.932
rs2027349	VPS45	VPS45_3_gene	SETDB1	-0.058	0.531	0.539	0.932
rs7170068	CHRNA3	CHRNA3_2_gene	LINGO1	-0.0978	0.554	0.556	0.932
rs12716973	KCTD13	KCTD13_2_gene	FAM57B	-0.108	0.56	0.559	0.932
rs4151680	PCDHA123	PCDHA123_2_gene	NDUFA2	-0.0234	0.563	0.557	0.932
rs2027349	VPS45	VPS45_2_gene	ARNT	-0.0236	0.565	0.558	0.932
rs3861678	LINC00637	LINC00637_2_gene	BAG5	-0.0382	0.568	0.562	0.932
rs10933	PBRM1	PBRM1_1_gene	ALAS1	-0.0592	0.563	0.562	0.932
rs10933	PBRM1	PBRM1_3_gene	RPL29	-0.0702	0.565	0.562	0.932
rs186132169	NGEF	NGEF_3_gene	DIS3L2	-0.0694	0.576	0.568	0.939
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA10	-0.0384	0.574	0.567	0.939
rs10933	PBRM1	PBRM1_1_gene	PHF7	-0.0608	0.571	0.57	0.94
rs4151680	PCDHA123	PCDHA123_1_gene	SLC35A4	0.0285	0.579	0.572	0.94
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	WDR73	0.0483	0.585	0.572	0.94
rs324015	STAT6	STAT6_3_gene	CS	-0.031	0.578	0.573	0.941
rs12716973	KCTD13	KCTD13_1_gene	ZNF768	-0.0348	0.579	0.582	0.944
rs12716973	KCTD13	KCTD13_2_gene	KIF22	-0.0904	0.584	0.583	0.944
rs3861678	LINC00637	LINC00637_1_gene	EIF5	-0.0405	0.578	0.578	0.944
rs186132169	NGEF	NGEF_1_gene	ECEL1	-0.3	0.581	0.577	0.944
rs10933	PBRM1	PBRM1_2_gene	ABHD14B	0.0578	0.58	0.58	0.944
rs324015	STAT6	STAT6_3_gene	COQ10A	-0.0386	0.588	0.583	0.944
rs324015	STAT6	STAT6_3_gene	METTL1	-0.0322	0.586	0.582	0.944
rs2027349	VPS45	VPS45_1_gene	TARS2	0.0495	0.58	0.579	0.944
rs12716973	KCTD13	KCTD13_2_gene	SEPHS2	0.0614	0.586	0.584	0.944
rs7148456	BAG5	BAG5_2_gene	TRAF3	0.032	0.577	0.588	0.946
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB10	-0.0373	0.594	0.588	0.946
rs7148456	BAG5	BAG5_1_gene	CKB	-0.0713	0.617	0.611	0.947
rs7148456	BAG5	BAG5_2_gene	CDC42BPB	-0.026	0.654	0.663	0.947
rs7148456	BAG5	BAG5_2_gene	CKB	0.0527	0.66	0.669	0.947
rs7148456	BAG5	BAG5_2_gene	EIF5	-0.0304	0.66	0.67	0.947
rs7148456	BAG5	BAG5_3_gene	MARK3	0.0355	0.673	0.682	0.947
rs12895055	BCL11B	BCL11B_2_gene	CYP46A1	-0.0416	0.601	0.606	0.947
rs7170068	CHRNA3	CHRNA3_1_gene	LINGO1	-0.111	0.609	0.597	0.947
rs7170068	CHRNA3	CHRNA3_1_gene	MORF4L1	0.0411	0.665	0.655	0.947
rs7170068	CHRNA3	CHRNA3_1_gene	TBC1D2B	0.0528	0.652	0.642	0.947
rs7170068	CHRNA3	CHRNA3_1_gene	WDR61	-0.0407	0.666	0.656	0.947
rs7170068	CHRNA3	CHRNA3_2_gene	ADAMTS7	-0.0448	0.595	0.597	0.947
rs7170068	CHRNA3	CHRNA3_2_gene	MORF4L1	-0.0349	0.63	0.631	0.947
rs520843	GALNT10	GALNT10_2_gene	GRIA1	0.0446	0.61	0.605	0.947
rs520843	GALNT10	GALNT10_2_gene	LARP1	-0.0284	0.651	0.645	0.947
rs12716973	KCTD13	KCTD13_1_gene	FBRS	-0.0329	0.617	0.62	0.947
rs12716973	KCTD13	KCTD13_2_gene	DCTPP1	-0.0476	0.607	0.606	0.947
rs12716973	KCTD13	KCTD13_2_gene	FBXL19	-0.0355	0.684	0.682	0.947
rs12716973	KCTD13	KCTD13_2_gene	ZNF48	-0.0436	0.635	0.634	0.947
rs12716973	KCTD13	KCTD13_3_gene	CDIPT	0.0609	0.608	0.607	0.947
rs12716973	KCTD13	KCTD13_3_gene	CORO1A	-0.089	0.613	0.611	0.947
rs12716973	KCTD13	KCTD13_3_gene	FBXL19	-0.0473	0.682	0.681	0.947
rs12716973	KCTD13	KCTD13_3_gene	KCTD13	0.0544	0.68	0.679	0.947
rs12716973	KCTD13	KCTD13_3_gene	MAZ	-0.0503	0.662	0.661	0.947
rs12716973	KCTD13	KCTD13_3_gene	NFATC2IP	0.0566	0.611	0.61	0.947
rs12716973	KCTD13	KCTD13_3_gene	QPRT	-0.0772	0.672	0.671	0.947
rs12716973	KCTD13	KCTD13_3_gene	TBC1D10B	-0.0566	0.612	0.611	0.947
rs12716973	KCTD13	KCTD13_3_gene	ZNF785	-0.0596	0.648	0.647	0.947
rs2192932	KMT2E	KMT2E_1_gene	ATXN7L1	-0.0556	0.677	0.675	0.947
rs2192932	KMT2E	KMT2E_1_gene	PUS7	-0.0581	0.653	0.651	0.947
rs3861678	LINC00637	LINC00637_1_gene	CDC42BPB	0.0324	0.595	0.595	0.947
rs3861678	LINC00637	LINC00637_1_gene	MARK3	0.0256	0.645	0.645	0.947
rs3861678	LINC00637	LINC00637_1_gene	ZFYVE21	0.0225	0.673	0.673	0.947
rs3861678	LINC00637	LINC00637_2_gene	SIVA1	-0.0405	0.636	0.631	0.947
rs3861678	LINC00637	LINC00637_3_gene	APOPT1	-0.0243	0.613	0.612	0.947
rs7936858	LOC100507431	LOC100507431_1_gene	SNX19	-0.0468	0.604	0.6	0.947
rs7936858	LOC100507431	LOC100507431_2_gene	ZBTB44	-0.0329	0.681	0.677	0.947
rs7936858	LOC100507431	LOC100507431_3_gene	ZBTB44	0.0261	0.64	0.642	0.947
rs17200916	LOC105376975	LOC105376975_1_gene	SATB1	-0.0407	0.635	0.64	0.947
rs17200916	LOC105376975	LOC105376975_2_gene	TBC1D5	0.0217	0.643	0.647	0.947
rs17200916	LOC105376975	LOC105376975_3_gene	PLCL2	-0.0522	0.636	0.637	0.947
rs1198588	miR137	miR137_2_gene	SNX7	-0.0298	0.666	0.662	0.947
rs324017	NAB2	NAB2_1_gene	DDIT3	-0.0541	0.67	0.662	0.947
rs324017	NAB2	NAB2_1_gene	MBD6	-0.0302	0.626	0.618	0.947
rs324017	NAB2	NAB2_1_gene	SPRYD4	0.0242	0.678	0.671	0.947
rs324017	NAB2	NAB2_2_gene	CS	-0.0318	0.642	0.646	0.947
rs324017	NAB2	NAB2_2_gene	MARS	0.0327	0.663	0.667	0.947
rs324017	NAB2	NAB2_3_gene	DTX3	-0.0404	0.631	0.633	0.947
rs324017	NAB2	NAB2_3_gene	KIF5A	-0.0735	0.643	0.645	0.947
rs324017	NAB2	NAB2_3_gene	PA2G4	-0.0356	0.673	0.675	0.947
rs324017	NAB2	NAB2_3_gene	PRIM1	-0.0436	0.642	0.644	0.947
rs324017	NAB2	NAB2_3_gene	SMARCC2	0.0407	0.64	0.643	0.947
rs324017	NAB2	NAB2_3_gene	TSPAN31	0.0315	0.653	0.655	0.947
rs186132169	NGEF	NGEF_1_gene	ATG16L1	0.0452	0.678	0.675	0.947
rs10933	PBRM1	PBRM1_1_gene	DCP1A	-0.0449	0.68	0.679	0.947
rs10933	PBRM1	PBRM1_2_gene	DCP1A	0.0464	0.655	0.655	0.947
rs10933	PBRM1	PBRM1_2_gene	RPL29	0.0591	0.609	0.609	0.947
rs10933	PBRM1	PBRM1_2_gene	TEX264	-0.0463	0.632	0.632	0.947
rs10933	PBRM1	PBRM1_3_gene	DCP1A	0.0474	0.665	0.663	0.947
rs10933	PBRM1	PBRM1_3_gene	PHF7	-0.0515	0.633	0.631	0.947
rs10933	PBRM1	PBRM1_3_gene	RFT1	-0.0445	0.649	0.646	0.947
rs4151680	PCDHA123	PCDHA123_1_gene	IK	0.0284	0.675	0.669	0.947
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB9	-0.0315	0.692	0.686	0.947
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHGB6	-0.0326	0.684	0.678	0.947
rs4151680	PCDHA123	PCDHA123_1_gene	ZMAT2	0.0227	0.666	0.66	0.947
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB2	-0.0284	0.596	0.592	0.947
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHGA7	-0.0288	0.686	0.683	0.947
rs6071578	PPP1R16B	PPP1R16B_1_gene	SNHG11	0.0331	0.581	0.592	0.947
rs6071578	PPP1R16B	PPP1R16B_2_gene	RPRD1B	0.0233	0.684	0.683	0.947
rs6071578	PPP1R16B	PPP1R16B_3_gene	ACTR5	0.03	0.636	0.635	0.947
rs301791	RERE	RERE_1_gene	RERE	-0.0258	0.637	0.635	0.947
rs301791	RERE	RERE_2_gene	ERRFI1	-0.041	0.609	0.608	0.947
rs301791	RERE	RERE_2_gene	VAMP3	-0.0335	0.646	0.645	0.947
rs301791	RERE	RERE_3_gene	ENO1	-0.0483	0.602	0.605	0.947
rs301791	RERE	RERE_3_gene	ERRFI1	-0.046	0.607	0.61	0.947
rs301791	RERE	RERE_3_gene	PARK7	-0.0221	0.674	0.676	0.947
rs301791	RERE	RERE_3_gene	VAMP3	-0.0347	0.67	0.672	0.947
rs324015	STAT6	STAT6_1_gene	MBD6	-0.0347	0.597	0.598	0.947
rs324015	STAT6	STAT6_1_gene	RNF41	0.0258	0.686	0.686	0.947
rs324015	STAT6	STAT6_2_gene	ATP23	-0.0216	0.675	0.683	0.947
rs324015	STAT6	STAT6_2_gene	B4GALNT1	-0.0408	0.601	0.61	0.947
rs324015	STAT6	STAT6_2_gene	CS	-0.0225	0.667	0.676	0.947
rs324015	STAT6	STAT6_2_gene	NXPH4	-0.0761	0.677	0.685	0.947
rs324015	STAT6	STAT6_2_gene	SHMT2	0.0317	0.634	0.643	0.947
rs324015	STAT6	STAT6_2_gene	TSFM	0.0248	0.615	0.624	0.947
rs324015	STAT6	STAT6_3_gene	ARHGEF25	0.0257	0.676	0.672	0.947
rs324015	STAT6	STAT6_3_gene	PIP4K2C	0.0247	0.687	0.683	0.947
rs324015	STAT6	STAT6_3_gene	RNF41	-0.0311	0.594	0.59	0.947
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	AKAP13	-0.0695	0.614	0.618	0.947
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	SEC11A	0.0434	0.677	0.682	0.947
rs2027349	VPS45	VPS45_1_gene	HIST2H2AC	0.098	0.615	0.614	0.947
rs2027349	VPS45	VPS45_1_gene	MRPS21	-0.0351	0.657	0.656	0.947
rs2027349	VPS45	VPS45_2_gene	HIST2H2BE	0.0263	0.638	0.631	0.947
rs2027349	VPS45	VPS45_2_gene	MRPS21	0.0166	0.645	0.638	0.947
rs2027349	VPS45	VPS45_2_gene	SETDB1	-0.0193	0.648	0.641	0.947
rs2027349	VPS45	VPS45_3_gene	GOLPH3L	-0.0415	0.638	0.645	0.947
rs2027349	VPS45	VPS45_3_gene	OTUD7B	0.0456	0.642	0.649	0.947
rs324015	STAT6	STAT6_2_gene	LRP1	0.0257	0.68	0.688	0.947
rs324015	STAT6	STAT6_2_gene	TIMELESS	-0.0275	0.681	0.689	0.947
rs7170068	CHRNA3	CHRNA3_3_gene	ADAMTS7	0.0382	0.695	0.693	0.949
rs324017	NAB2	NAB2_3_gene	LRP1	0.0324	0.691	0.693	0.949
rs10933	PBRM1	PBRM1_1_gene	SMIM4	-0.0412	0.693	0.692	0.949
rs324017	NAB2	NAB2_2_gene	STAT2	-0.0279	0.693	0.697	0.95
rs4151680	PCDHA123	PCDHA123_3_gene	RELL2	-0.021	0.699	0.697	0.95
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ZNF592	0.0325	0.706	0.696	0.95
rs324015	STAT6	STAT6_1_gene	DCTN2	0.0246	0.699	0.699	0.951
rs12716973	KCTD13	KCTD13_1_gene	DCTPP1	-0.0275	0.701	0.703	0.951
rs10933	PBRM1	PBRM1_2_gene	NISCH	-0.0406	0.702	0.702	0.951
rs4151680	PCDHA123	PCDHA123_1_gene	HDAC3	0.0189	0.706	0.7	0.951
rs324015	STAT6	STAT6_1_gene	SHMT2	0.0296	0.703	0.703	0.951
rs10933	PBRM1	PBRM1_3_gene	GLT8D1	-0.0376	0.71	0.708	0.955
rs4151680	PCDHA123	PCDHA123_3_gene	ANKHD1	0.0148	0.71	0.708	0.955
rs4151680	PCDHA123	PCDHA123_3_gene	HDAC3	-0.0141	0.711	0.709	0.955
rs10933	PBRM1	PBRM1_1_gene	ABHD14B	0.0405	0.712	0.711	0.955
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	SEC11A	0.0387	0.708	0.711	0.955
rs324015	STAT6	STAT6_3_gene	OS9	-0.0202	0.715	0.712	0.955
rs7936858	LOC100507431	LOC100507431_1_gene	NTM	0.107	0.719	0.716	0.958
rs7148456	BAG5	BAG5_1_gene	PPP1R13B	-0.0267	0.726	0.722	0.965
rs10933	PBRM1	PBRM1_1_gene	RRP9	0.0382	0.724	0.724	0.966
rs7148456	BAG5	BAG5_3_gene	PPP1R13B	0.0359	0.725	0.733	0.967
rs324017	NAB2	NAB2_1_gene	MYL6B	-0.0223	0.74	0.734	0.967
rs324017	NAB2	NAB2_2_gene	BAZ2A	-0.0269	0.731	0.734	0.967
rs324017	NAB2	NAB2_2_gene	LRP1	-0.0285	0.727	0.73	0.967
rs4151680	PCDHA123	PCDHA123_1_gene	TAF7	-0.0233	0.733	0.729	0.967
rs4151680	PCDHA123	PCDHA123_2_gene	PSD2	0.0191	0.736	0.732	0.967
rs4151680	PCDHA123	PCDHA123_3_gene	TAF7	0.0178	0.732	0.73	0.967
rs6071578	PPP1R16B	PPP1R16B_1_gene	VSTM2L	-0.0478	0.719	0.726	0.967
rs2027349	VPS45	VPS45_1_gene	SETDB1	-0.0317	0.734	0.734	0.967
rs2027349	VPS45	VPS45_2_gene	C1orf56	-0.0155	0.734	0.728	0.967
rs12895055	BCL11B	BCL11B_1_gene	CCDC85C	-0.0344	0.732	0.737	0.967
rs324015	STAT6	STAT6_1_gene	RPL41	0.0293	0.736	0.736	0.967
rs7148456	BAG5	BAG5_1_gene	EIF5	0.0212	0.797	0.793	0.967
rs7148456	BAG5	BAG5_3_gene	CDC42BPB	-0.0306	0.74	0.748	0.967
rs7148456	BAG5	BAG5_3_gene	ZFYVE21	0.0235	0.77	0.777	0.967
rs7170068	CHRNA3	CHRNA3_1_gene	CTSH	0.0343	0.792	0.786	0.967
rs7170068	CHRNA3	CHRNA3_1_gene	IDH3A	0.0349	0.795	0.788	0.967
rs7170068	CHRNA3	CHRNA3_3_gene	CIB2	0.0415	0.786	0.785	0.967
rs7170068	CHRNA3	CHRNA3_3_gene	CTSH	-0.0315	0.783	0.782	0.967
rs7170068	CHRNA3	CHRNA3_3_gene	LINGO1	0.0587	0.758	0.756	0.967
rs7170068	CHRNA3	CHRNA3_3_gene	TBC1D2B	0.0315	0.76	0.758	0.967
rs9661794	DPYD	DPYD_3_gene	SNX7	-0.0216	0.755	0.756	0.967
rs520843	GALNT10	GALNT10_1_gene	GALNT10	-0.0182	0.788	0.786	0.967
rs520843	GALNT10	GALNT10_3_gene	GEMIN5	-0.0145	0.764	0.766	0.967
rs12716973	KCTD13	KCTD13_2_gene	NFATC2IP	-0.0263	0.753	0.752	0.967
rs12716973	KCTD13	KCTD13_2_gene	QPRT	0.0361	0.793	0.791	0.967
rs12716973	KCTD13	KCTD13_2_gene	TBC1D10B	-0.0228	0.786	0.785	0.967
rs12716973	KCTD13	KCTD13_2_gene	YPEL3	-0.0331	0.783	0.781	0.967
rs12716973	KCTD13	KCTD13_3_gene	PHKG2	-0.0291	0.784	0.784	0.967
rs12716973	KCTD13	KCTD13_3_gene	ZNF764	-0.0305	0.791	0.791	0.967
rs3861678	LINC00637	LINC00637_2_gene	AKT1	-0.0188	0.741	0.738	0.967
rs17200916	LOC105376975	LOC105376975_1_gene	TBC1D5	-0.0172	0.786	0.788	0.967
rs17200916	LOC105376975	LOC105376975_2_gene	SATB1	-0.017	0.789	0.793	0.967
rs324017	NAB2	NAB2_1_gene	PTGES3	-0.0196	0.756	0.75	0.967
rs324017	NAB2	NAB2_1_gene	RPL41	0.0225	0.784	0.779	0.967
rs324017	NAB2	NAB2_1_gene	TIMELESS	0.0206	0.779	0.775	0.967
rs324017	NAB2	NAB2_2_gene	CNPY2	-0.0228	0.741	0.744	0.967
rs324017	NAB2	NAB2_3_gene	METTL1	0.0236	0.745	0.747	0.967
rs324017	NAB2	NAB2_3_gene	STAT2	-0.0233	0.741	0.744	0.967
rs186132169	NGEF	NGEF_3_gene	GIGYF2	0.0408	0.762	0.756	0.967
rs10933	PBRM1	PBRM1_1_gene	TEX264	-0.0268	0.792	0.792	0.967
rs10933	PBRM1	PBRM1_2_gene	NEK4	0.0329	0.745	0.745	0.967
rs10933	PBRM1	PBRM1_2_gene	RFT1	-0.0245	0.791	0.791	0.967
rs10933	PBRM1	PBRM1_3_gene	SMIM4	-0.0341	0.746	0.744	0.967
rs4151680	PCDHA123	PCDHA123_1_gene	WDR55	0.0155	0.767	0.763	0.967
rs4151680	PCDHA123	PCDHA123_2_gene	CYSTM1	0.0262	0.752	0.748	0.967
rs4151680	PCDHA123	PCDHA123_2_gene	HDAC3	-0.0108	0.796	0.792	0.967
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB2	0.0157	0.788	0.784	0.967
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB5	0.0133	0.789	0.788	0.967
rs4151680	PCDHA123	PCDHA123_3_gene	PSD2	-0.0146	0.779	0.778	0.967
rs6071578	PPP1R16B	PPP1R16B_3_gene	RALGAPB	-0.0163	0.795	0.793	0.967
rs301791	RERE	RERE_1_gene	ERRFI1	-0.0162	0.789	0.788	0.967
rs301791	RERE	RERE_2_gene	ENO1	0.0247	0.766	0.765	0.967
rs301791	RERE	RERE_2_gene	RERE	-0.0203	0.779	0.777	0.967
rs324015	STAT6	STAT6_1_gene	KIF5A	-0.0437	0.757	0.757	0.967
rs324015	STAT6	STAT6_1_gene	LRP1	0.0212	0.77	0.769	0.967
rs324015	STAT6	STAT6_1_gene	NXPH4	0.0619	0.77	0.77	0.967
rs324015	STAT6	STAT6_1_gene	PIP4K2C	0.021	0.753	0.753	0.967
rs324015	STAT6	STAT6_1_gene	TSPAN31	0.0204	0.743	0.743	0.967
rs324015	STAT6	STAT6_2_gene	COQ10A	-0.0185	0.783	0.788	0.967
rs324015	STAT6	STAT6_2_gene	MARCH9	-0.02	0.761	0.766	0.967
rs324015	STAT6	STAT6_2_gene	TSPAN31	0.0175	0.744	0.751	0.967
rs9882911	TRANK1	TRANK1_2_gene	LRRFIP2	-0.0241	0.769	0.768	0.967
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	WDR73	0.0342	0.75	0.753	0.967
rs2027349	VPS45	VPS45_2_gene	BOLA1	0.0123	0.773	0.768	0.967
rs2027349	VPS45	VPS45_3_gene	ENSA	-0.0254	0.759	0.764	0.967
rs12716973	KCTD13	KCTD13_1_gene	INO80E	-0.0156	0.797	0.798	0.968
rs12716973	KCTD13	KCTD13_3_gene	INO80E	0.0264	0.8	0.8	0.968
rs3861678	LINC00637	LINC00637_1_gene	CKB	-0.0322	0.798	0.798	0.968
rs3861678	LINC00637	LINC00637_3_gene	INF2	0.0127	0.798	0.798	0.968
rs324017	NAB2	NAB2_1_gene	ZC3H10	-0.0163	0.801	0.797	0.968
rs12716973	KCTD13	KCTD13_2_gene	ZNF689	0.0217	0.807	0.806	0.973
rs301791	RERE	RERE_2_gene	CAMTA1	0.0145	0.806	0.805	0.973
rs12895055	BCL11B	BCL11B_2_gene	EML1	0.0125	0.809	0.812	0.974
rs7936858	LOC100507431	LOC100507431_1_gene	NFRKB	-0.021	0.815	0.812	0.974
rs4151680	PCDHA123	PCDHA123_1_gene	PSD2	-0.0163	0.812	0.808	0.974
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB16	0.0139	0.81	0.809	0.974
rs324015	STAT6	STAT6_1_gene	PA2G4	0.0179	0.812	0.811	0.974
rs12895055	BCL11B	BCL11B_1_gene	CYP46A1	0.0291	0.82	0.823	0.975
rs12895055	BCL11B	BCL11B_2_gene	EVL	-0.0173	0.836	0.838	0.975
rs12895055	BCL11B	BCL11B_2_gene	YY1	-0.014	0.82	0.823	0.975
rs7170068	CHRNA3	CHRNA3_2_gene	CIB2	0.0299	0.822	0.823	0.975
rs7170068	CHRNA3	CHRNA3_3_gene	CRABP1	0.472	0.823	0.821	0.975
rs7170068	CHRNA3	CHRNA3_3_gene	TMED3	-0.0247	0.837	0.836	0.975
rs12716973	KCTD13	KCTD13_1_gene	CORO1A	-0.0213	0.835	0.836	0.975
rs12716973	KCTD13	KCTD13_1_gene	MVP	-0.0194	0.837	0.838	0.975
rs12716973	KCTD13	KCTD13_1_gene	PRRT2	0.0215	0.83	0.831	0.975
rs3861678	LINC00637	LINC00637_3_gene	TRMT61A	-0.01	0.838	0.839	0.975
rs324017	NAB2	NAB2_1_gene	KIF5A	-0.0272	0.839	0.835	0.975
rs186132169	NGEF	NGEF_1_gene	GIGYF2	-0.0242	0.828	0.826	0.975
rs10933	PBRM1	PBRM1_3_gene	TWF2	-0.022	0.83	0.828	0.975
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB2	0.0161	0.82	0.816	0.975
rs6071578	PPP1R16B	PPP1R16B_2_gene	VSTM2L	0.0294	0.839	0.838	0.975
rs6071578	PPP1R16B	PPP1R16B_3_gene	CTNNBL1	-0.0116	0.834	0.833	0.975
rs301791	RERE	RERE_1_gene	SPSB1	-0.0127	0.828	0.827	0.975
rs324015	STAT6	STAT6_1_gene	DDIT3	0.0274	0.839	0.838	0.975
rs324015	STAT6	STAT6_1_gene	NABP2	-0.0147	0.814	0.813	0.975
rs324015	STAT6	STAT6_2_gene	PA2G4	-0.0154	0.812	0.817	0.975
rs324015	STAT6	STAT6_2_gene	PRIM1	-0.0165	0.818	0.824	0.975
rs324015	STAT6	STAT6_3_gene	CTDSP2	-0.0144	0.821	0.82	0.975
rs324015	STAT6	STAT6_3_gene	LRP1	0.0137	0.837	0.836	0.975
rs2027349	VPS45	VPS45_1_gene	HIST2H2BE	-0.0263	0.83	0.83	0.975
rs2027349	VPS45	VPS45_2_gene	SF3B4	0.00937	0.823	0.819	0.975
rs10933	PBRM1	PBRM1_3_gene	TKT	0.0212	0.841	0.84	0.975
rs520843	GALNT10	GALNT10_2_gene	CNOT8	-0.0119	0.849	0.847	0.978
rs12716973	KCTD13	KCTD13_1_gene	NFATC2IP	-0.0122	0.851	0.851	0.978
rs3861678	LINC00637	LINC00637_3_gene	ADSSL1	0.0112	0.844	0.845	0.978
rs324017	NAB2	NAB2_1_gene	PIP4K2C	0.0118	0.852	0.849	0.978
rs324017	NAB2	NAB2_2_gene	B4GALNT1	0.0193	0.85	0.851	0.978
rs4151680	PCDHA123	PCDHA123_2_gene	PURA	-0.00973	0.856	0.853	0.978
rs4151680	PCDHA123	PCDHA123_2_gene	RELL2	-0.011	0.853	0.851	0.978
rs324015	STAT6	STAT6_2_gene	CNPY2	0.0101	0.849	0.853	0.978
rs324015	STAT6	STAT6_3_gene	CDK4	-0.0187	0.854	0.853	0.978
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ZSCAN2	-0.0205	0.851	0.853	0.978
rs12716973	KCTD13	KCTD13_3_gene	ASPHD1	-0.0343	0.857	0.857	0.982
rs2027349	VPS45	VPS45_1_gene	CDC42SE1	0.0165	0.859	0.859	0.982
rs12895055	BCL11B	BCL11B_1_gene	YY1	-0.0156	0.874	0.876	0.982
rs12895055	BCL11B	BCL11B_2_gene	CCDC85C	-0.0107	0.864	0.865	0.982
rs12895055	BCL11B	BCL11B_3_gene	EML1	-0.0137	0.86	0.861	0.982
rs520843	GALNT10	GALNT10_1_gene	GRIA1	0.0114	0.881	0.879	0.982
rs12716973	KCTD13	KCTD13_1_gene	FBXL19	0.0104	0.877	0.877	0.982
rs12716973	KCTD13	KCTD13_1_gene	HIRIP3	-0.0126	0.872	0.873	0.982
rs12716973	KCTD13	KCTD13_2_gene	ASPHD1	0.0207	0.885	0.883	0.982
rs12716973	KCTD13	KCTD13_3_gene	PRRT2	0.0285	0.868	0.869	0.982
rs12716973	KCTD13	KCTD13_3_gene	SEZ6L2	0.0365	0.883	0.884	0.982
rs3861678	LINC00637	LINC00637_2_gene	KLC1	0.0156	0.879	0.878	0.982
rs3861678	LINC00637	LINC00637_3_gene	AKT1	0.00798	0.868	0.867	0.982
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHGA7	-0.0116	0.882	0.879	0.982
rs4151680	PCDHA123	PCDHA123_3_gene	SRA1	-0.00719	0.869	0.869	0.982
rs6071578	PPP1R16B	PPP1R16B_2_gene	SNHG11	-0.0107	0.87	0.869	0.982
rs6071578	PPP1R16B	PPP1R16B_3_gene	RPRD1B	-0.00913	0.88	0.879	0.982
rs301791	RERE	RERE_1_gene	CAMTA1	-0.0072	0.873	0.872	0.982
rs301791	RERE	RERE_3_gene	SPSB1	-0.014	0.87	0.871	0.982
rs324015	STAT6	STAT6_1_gene	ESYT1	-0.0094	0.881	0.88	0.982
rs324015	STAT6	STAT6_1_gene	PTGES3	-0.0108	0.872	0.872	0.982
rs324015	STAT6	STAT6_2_gene	STAT2	0.00892	0.869	0.872	0.982
rs324015	STAT6	STAT6_3_gene	TSFM	-0.00764	0.884	0.884	0.982
rs2027349	VPS45	VPS45_2_gene	PLEKHO1	0.0069	0.877	0.874	0.982
rs2027349	VPS45	VPS45_3_gene	C1orf56	-0.0167	0.867	0.869	0.982
rs12895055	BCL11B	BCL11B_2_gene	SETD3	0.00587	0.905	0.906	0.983
rs520843	GALNT10	GALNT10_1_gene	LARP1	0.00612	0.911	0.91	0.983
rs12716973	KCTD13	KCTD13_1_gene	CDIPT	-0.0087	0.9	0.9	0.983
rs12716973	KCTD13	KCTD13_1_gene	KIF22	-0.0154	0.904	0.904	0.983
rs12716973	KCTD13	KCTD13_1_gene	ZNF629	-0.00741	0.911	0.912	0.983
rs12716973	KCTD13	KCTD13_2_gene	CDIPT	0.0123	0.89	0.888	0.983
rs2192932	KMT2E	KMT2E_2_gene	SRPK2	0.00967	0.908	0.907	0.983
rs3861678	LINC00637	LINC00637_1_gene	BAG5	0.00695	0.91	0.911	0.983
rs3861678	LINC00637	LINC00637_1_gene	TRMT61A	0.00563	0.917	0.918	0.983
rs324017	NAB2	NAB2_1_gene	CDK4	0.0129	0.902	0.9	0.983
rs324017	NAB2	NAB2_2_gene	DDIT3	0.02	0.895	0.895	0.983
rs324017	NAB2	NAB2_3_gene	MYL6B	0.0104	0.896	0.897	0.983
rs10933	PBRM1	PBRM1_1_gene	RPL29	0.0124	0.919	0.918	0.983
rs10933	PBRM1	PBRM1_1_gene	TKT	0.0107	0.919	0.918	0.983
rs10933	PBRM1	PBRM1_2_gene	WDR82	0.0106	0.917	0.918	0.983
rs10933	PBRM1	PBRM1_3_gene	SPCS1	0.0102	0.91	0.91	0.983
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHGA10	0.00765	0.913	0.911	0.983
rs4151680	PCDHA123	PCDHA123_2_gene	IK	-0.00656	0.907	0.905	0.983
rs301791	RERE	RERE_1_gene	SLC45A1	-0.00696	0.906	0.907	0.983
rs324015	STAT6	STAT6_1_gene	ATP23	0.00637	0.915	0.915	0.983
rs324015	STAT6	STAT6_1_gene	BAZ2A	0.00801	0.908	0.908	0.983
rs324015	STAT6	STAT6_1_gene	NAB2	-0.00979	0.898	0.898	0.983
rs324015	STAT6	STAT6_1_gene	OS9	-0.00668	0.912	0.912	0.983
rs324015	STAT6	STAT6_2_gene	OS9	-0.0062	0.905	0.908	0.983
rs324015	STAT6	STAT6_3_gene	PTGES3	0.00875	0.886	0.885	0.983
rs324015	STAT6	STAT6_3_gene	RPL41	0.0097	0.903	0.902	0.983
rs9882911	TRANK1	TRANK1_2_gene	GOLGA4	-0.0137	0.889	0.888	0.983
rs9882911	TRANK1	TRANK1_3_gene	MLH1	-0.00543	0.897	0.896	0.983
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ZNF592	-0.0129	0.901	0.903	0.983
rs2027349	VPS45	VPS45_2_gene	CDC42SE1	-0.00566	0.893	0.89	0.983
rs2027349	VPS45	VPS45_2_gene	ENSA	0.00444	0.907	0.905	0.983
rs2027349	VPS45	VPS45_2_gene	PRPF3	0.00492	0.916	0.914	0.983
rs7148456	BAG5	BAG5_1_gene	ZFYVE21	-0.00582	0.923	0.922	0.983
rs7170068	CHRNA3	CHRNA3_2_gene	IDH3A	0.00984	0.923	0.923	0.983
rs12716973	KCTD13	KCTD13_2_gene	SEPT1	0.006	0.944	0.943	0.983
rs2192932	KMT2E	KMT2E_1_gene	RINT1	-0.0104	0.936	0.936	0.983
rs17200916	LOC105376975	LOC105376975_1_gene	PLCL2	0.007	0.935	0.936	0.983
rs324017	NAB2	NAB2_1_gene	CTDSP2	0.00465	0.943	0.942	0.983
rs324017	NAB2	NAB2_1_gene	STAT2	-0.00428	0.942	0.941	0.983
rs324017	NAB2	NAB2_1_gene	TSPAN31	-0.00424	0.943	0.942	0.983
rs324017	NAB2	NAB2_2_gene	ANKRD52	-0.00493	0.943	0.944	0.983
rs324017	NAB2	NAB2_3_gene	ANKRD52	0.00592	0.932	0.933	0.983
rs324017	NAB2	NAB2_3_gene	DCTN2	0.00572	0.936	0.937	0.983
rs10933	PBRM1	PBRM1_2_gene	CACNA1D	0.0114	0.935	0.936	0.983
rs10933	PBRM1	PBRM1_3_gene	NEK4	-0.0101	0.925	0.925	0.983
rs4151680	PCDHA123	PCDHA123_2_gene	ANKHD1	0.00394	0.928	0.926	0.983
rs4151680	PCDHA123	PCDHA123_3_gene	PURA	0.00429	0.93	0.93	0.983
rs6071578	PPP1R16B	PPP1R16B_1_gene	CTNNBL1	0.00392	0.935	0.938	0.983
rs324015	STAT6	STAT6_1_gene	MARCH9	-0.00709	0.926	0.926	0.983
rs324015	STAT6	STAT6_2_gene	ARHGEF25	0.00548	0.925	0.927	0.983
rs324015	STAT6	STAT6_2_gene	ZC3H10	-0.00576	0.922	0.924	0.983
rs324015	STAT6	STAT6_3_gene	BAZ2A	-0.00478	0.94	0.94	0.983
rs324015	STAT6	STAT6_3_gene	TIMELESS	0.00631	0.929	0.929	0.983
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ZSCAN2	-0.00756	0.934	0.931	0.983
rs2027349	VPS45	VPS45_1_gene	C1orf54	-0.0229	0.926	0.926	0.983
rs2027349	VPS45	VPS45_1_gene	GOLPH3L	0.00682	0.939	0.939	0.983
rs10933	PBRM1	PBRM1_1_gene	TWF2	0.00691	0.946	0.945	0.983
rs520843	GALNT10	GALNT10_1_gene	GEMIN5	0.00319	0.952	0.952	0.984
rs520843	GALNT10	GALNT10_1_gene	SAP30L	0.00342	0.948	0.947	0.984
rs12716973	KCTD13	KCTD13_1_gene	ZNF785	-0.00501	0.948	0.948	0.984
rs12716973	KCTD13	KCTD13_3_gene	BCL7C	-0.00786	0.95	0.95	0.984
rs324017	NAB2	NAB2_2_gene	ARHGEF25	-0.00478	0.95	0.95	0.984
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB14	0.00436	0.951	0.951	0.984
rs10933	PBRM1	PBRM1_1_gene	RFT1	0.00567	0.953	0.953	0.984
rs7148456	BAG5	BAG5_1_gene	MARK3	0.00323	0.959	0.958	0.987
rs520843	GALNT10	GALNT10_3_gene	GRIA1	-0.00371	0.957	0.958	0.987
rs7170068	CHRNA3	CHRNA3_1_gene	CIB2	-0.00692	0.968	0.967	0.988
rs12716973	KCTD13	KCTD13_1_gene	MAZ	-0.00327	0.961	0.961	0.988
rs2192932	KMT2E	KMT2E_1_gene	KMT2E	0.00838	0.962	0.961	0.988
rs2192932	KMT2E	KMT2E_2_gene	PUS7	-0.00287	0.967	0.967	0.988
rs3861678	LINC00637	LINC00637_3_gene	SIVA1	-0.00326	0.964	0.965	0.988
rs1198588	miR137	miR137_3_gene	SNX7	-0.00255	0.963	0.964	0.988
rs10933	PBRM1	PBRM1_3_gene	CACNA1D	-0.00658	0.965	0.964	0.988
rs324015	STAT6	STAT6_3_gene	TSPAN31	-0.00232	0.968	0.967	0.988
rs12716973	KCTD13	KCTD13_1_gene	CD2BP2	-0.00165	0.979	0.979	0.989
rs12716973	KCTD13	KCTD13_1_gene	TAOK2	-0.00173	0.977	0.978	0.989
rs12716973	KCTD13	KCTD13_2_gene	PHKG2	0.00251	0.975	0.975	0.989
rs3861678	LINC00637	LINC00637_2_gene	APOPT1	0.00171	0.976	0.975	0.989
rs324017	NAB2	NAB2_2_gene	NXPH4	-0.00847	0.972	0.972	0.989
rs324017	NAB2	NAB2_2_gene	SHMT2	-0.00306	0.972	0.972	0.989
rs324017	NAB2	NAB2_3_gene	BAZ2A	-0.0026	0.973	0.974	0.989
rs10933	PBRM1	PBRM1_2_gene	GLT8D1	-0.00341	0.972	0.972	0.989
rs4151680	PCDHA123	PCDHA123_2_gene	HARS	-0.00119	0.979	0.98	0.989
rs324015	STAT6	STAT6_3_gene	SHMT2	-0.00186	0.979	0.979	0.989
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	NMB	0.00282	0.982	0.982	0.99
rs324017	NAB2	NAB2_2_gene	RNF41	0.00147	0.984	0.984	0.991
rs324017	NAB2	NAB2_3_gene	MARS	-0.00148	0.984	0.985	0.991
rs324017	NAB2	NAB2_3_gene	SHMT2	-0.00164	0.985	0.985	0.991
rs2027349	VPS45	VPS45_3_gene	PLEKHO1	0.00167	0.986	0.986	0.991
rs2027349	VPS45	VPS45_2_gene	HIST2H2AC	-0.00123	0.989	0.989	0.992
rs12716973	KCTD13	KCTD13_3_gene	RNF40	-0.000167	0.999	0.999	0.999
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB9	0.000211	0.997	0.997	0.999
rs324015	STAT6	STAT6_1_gene	NACA	0.000111	0.998	0.998	0.999

cis pairs that passed FDR < 0.1: 5 

cis pairs that have an empirical p values < 0.05: 72

edgeR

Another DE method we tried is using edgeR QLF test directly on the raw UMI count matrix of the 8015 MAP2+ gRNA+ cells. We partitioned the cells into target / non-target groups the same way as before.

We observed significant inflation for small p values, so for each gRNA condition, we performed permutation 20 times by scrambling the labels of all cells and conducting the same edgeR QLF test on all genes (12091 with > 10% detection rate). Then, we used all 12091 \(\times\) 20 p values obtained from permutations as the null distribution to compute the empirical p value of each gene under each gRNA condition.

The null p value distribution of 1101 1Mb cis-gene - gRNA pairs over 20 permutations is shown here:

We can see that DE analysis using edgeR QLF test indeed results in inflation of small p values.

500 kb cis gene result

edgeR_cis_summary = readRDS(paste0(dir,'cis_analysis/result/edgeR_observed_summary/cis_summary_gRNA.MAP2_8015.genes_0.1_edgeR_w_empiricalP.rds'))
formatted.df = edgeR_cis_summary$cis_summary_500kb
fdr_num = dim(filter(formatted.df, pval_adj_cis < 0.1))[1]
pval_num = dim(filter(formatted.df, empirical_pval < 0.05))[1]
formatted.df = select(formatted.df, c('SNP','locus','gRNA','gene','logFC','PValue',
                                        'empirical_pval','pval_adj_cis')) %>% arrange(pval_adj_cis)
formatted.df[,5:8] = signif(formatted.df[,5:8], digits = 3)
mutate(formatted.df, 
       logFC = cell_spec(logFC, "html", color = ifelse(logFC < 0, "red", "blue")),
       PValue = cell_spec(PValue, "html", color = ifelse(PValue < 0.05, "orange", "black")),
       empirical_pval = cell_spec(empirical_pval, "html", color = ifelse(empirical_pval < 0.05, "orange", "black")),
       pval_adj_cis = cell_spec(pval_adj_cis, "html", color = ifelse(pval_adj_cis < 0.1, "red", "black")) ) %>% 
  kable(format = "html", escape = F) %>%
  kable_styling() %>% scroll_box(width = "100%", height = "400px")

SNP	locus	gRNA	gene	logFC	PValue	empirical_pval	pval_adj_cis
rs324017	NAB2	NAB2_2_gene	TAC3	-1.85	1.05e-31	4.14e-06	0.00254
rs324015	STAT6	STAT6_2_gene	TAC3	1.46	7.13e-28	2.89e-05	0.00763
rs2027349	VPS45	VPS45_2_gene	VPS45	-0.627	1.43e-20	3.72e-05	0.00763
rs2027349	VPS45	VPS45_3_gene	VPS45	-0.874	2.66e-08	0.000215	0.0331
rs10933	PBRM1	PBRM1_3_gene	PBRM1	-0.512	1.71e-05	0.000881	0.108
rs4151680	PCDHA123	PCDHA123_2_gene	HBEGF	0.428	7.54e-06	0.00116	0.119
rs7148456	BAG5	BAG5_2_gene	BAG5	0.248	0.000898	0.00567	0.218
rs324017	NAB2	NAB2_2_gene	RBMS2	-0.425	0.000932	0.00561	0.218
rs10933	PBRM1	PBRM1_3_gene	GNL3	-0.494	0.00094	0.00476	0.218
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA4	-0.356	0.000313	0.0036	0.218
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA12	0.232	0.000718	0.00514	0.218
rs6071578	PPP1R16B	PPP1R16B_3_gene	FAM83D	-0.562	0.00015	0.00296	0.218
rs324015	STAT6	STAT6_2_gene	NACA	0.126	0.000307	0.00338	0.218
rs2027349	VPS45	VPS45_2_gene	ECM1	0.329	0.000504	0.0045	0.218
rs2027349	VPS45	VPS45_3_gene	HIST2H2AC	-0.745	0.0012	0.00534	0.218
rs2027349	VPS45	VPS45_3_gene	HIST2H2BE	-0.68	0.00126	0.00546	0.218
rs324015	STAT6	STAT6_1_gene	TAC3	-0.646	0.0017	0.00697	0.238
rs324015	STAT6	STAT6_2_gene	STAT6	0.303	0.00148	0.00687	0.238
rs1198588	miR137	miR137_1_gene	MIR137HG	0.346	0.00237	0.00809	0.262
rs324017	NAB2	NAB2_1_gene	TAC3	0.567	0.00363	0.0106	0.284
rs4151680	PCDHA123	PCDHA123_3_gene	WDR55	0.216	0.0024	0.00938	0.284
rs301791	RERE	RERE_1_gene	PARK7	0.0863	0.00282	0.0105	0.284
rs2027349	VPS45	VPS45_2_gene	APH1A	0.16	0.00322	0.0106	0.284
rs7170068	CHRNA3	CHRNA3_3_gene	CHRNA3	0.73	0.00444	0.0134	0.294
rs186132169	NGEF	NGEF_3_gene	EFHD1	-0.754	0.0035	0.0117	0.294
rs10933	PBRM1	PBRM1_2_gene	TNNC1	0.592	0.00495	0.0132	0.294
rs10933	PBRM1	PBRM1_3_gene	TNNC1	-0.753	0.00644	0.0137	0.294
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	SEC11A	0.235	0.00393	0.0127	0.294
rs2027349	VPS45	VPS45_3_gene	ANP32E	0.433	0.00676	0.0139	0.294
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB9	0.246	0.00512	0.0144	0.295
rs12716973	KCTD13	KCTD13_2_gene	TMEM219	-0.253	0.00658	0.0163	0.299
rs10933	PBRM1	PBRM1_2_gene	PBRM1	-0.283	0.00858	0.0185	0.299
rs4151680	PCDHA123	PCDHA123_1_gene	NDUFA2	0.114	0.00946	0.0173	0.299
rs4151680	PCDHA123	PCDHA123_3_gene	APBB3	0.19	0.00772	0.0181	0.299
rs4151680	PCDHA123	PCDHA123_3_gene	HBEGF	0.243	0.0067	0.0166	0.299
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA4	-0.26	0.00778	0.0182	0.299
rs9882911	TRANK1	TRANK1_3_gene	GOLGA4	0.128	0.00802	0.0181	0.299
rs2027349	VPS45	VPS45_2_gene	C1orf54	0.24	0.00622	0.0154	0.299
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA6	0.203	0.0108	0.0223	0.314
rs6071578	PPP1R16B	PPP1R16B_1_gene	SLC32A1	-0.343	0.0105	0.0205	0.314
rs324015	STAT6	STAT6_1_gene	DCTN2	0.119	0.0108	0.0208	0.314
rs324015	STAT6	STAT6_1_gene	NACA	0.102	0.0117	0.0218	0.314
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	GOLGA6L4	-0.507	0.0101	0.0225	0.314
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	NMB	0.376	0.0093	0.0213	0.314
rs12716973	KCTD13	KCTD13_2_gene	KCTD13	0.379	0.0135	0.0259	0.346
rs10933	PBRM1	PBRM1_1_gene	NT5DC2	0.294	0.0149	0.0256	0.346
rs4151680	PCDHA123	PCDHA123_1_gene	HARS	0.133	0.0169	0.0268	0.351
rs7170068	CHRNA3	CHRNA3_2_gene	CHRNA3	0.516	0.0161	0.0296	0.364
rs4151680	PCDHA123	PCDHA123_1_gene	APBB3	0.217	0.0188	0.029	0.364
rs2027349	VPS45	VPS45_2_gene	MRPS21	0.0822	0.0164	0.0286	0.364
rs7170068	CHRNA3	CHRNA3_2_gene	DNAJA4	0.374	0.0189	0.0331	0.388
rs7170068	CHRNA3	CHRNA3_2_gene	PSMA4	-0.167	0.0188	0.0329	0.388
rs12716973	KCTD13	KCTD13_2_gene	SEZ6L2	-0.288	0.0201	0.0342	0.388
rs324017	NAB2	NAB2_1_gene	NXPH4	-0.315	0.023	0.0351	0.388
rs324017	NAB2	NAB2_2_gene	NDUFA4L2	-0.333	0.022	0.036	0.388
rs9882911	TRANK1	TRANK1_3_gene	LRRFIP2	0.124	0.0214	0.0354	0.388
rs2027349	VPS45	VPS45_3_gene	CIART	0.439	0.0246	0.0345	0.388
rs12716973	KCTD13	KCTD13_3_gene	ALDOA	-0.385	0.0254	0.0373	0.395
rs7148456	BAG5	BAG5_2_gene	XRCC3	-0.215	0.0245	0.0411	0.398
rs12716973	KCTD13	KCTD13_1_gene	ALDOA	-0.228	0.0261	0.044	0.398
rs12716973	KCTD13	KCTD13_1_gene	ZNF48	-0.215	0.0237	0.0411	0.398
rs12716973	KCTD13	KCTD13_3_gene	HIRIP3	-0.392	0.029	0.0412	0.398
rs3861678	LINC00637	LINC00637_2_gene	PPP1R13B	-0.233	0.028	0.0434	0.398
rs324017	NAB2	NAB2_1_gene	DCTN2	-0.0955	0.0308	0.044	0.398
rs324017	NAB2	NAB2_2_gene	PTGES3	-0.124	0.0276	0.0428	0.398
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB10	0.231	0.0273	0.0386	0.398
rs2027349	VPS45	VPS45_2_gene	ANP32E	0.167	0.0274	0.0412	0.398
rs2027349	VPS45	VPS45_3_gene	CA14	0.442	0.0315	0.0419	0.398
rs7148456	BAG5	BAG5_1_gene	XRCC3	-0.293	0.0296	0.048	0.41
rs4151680	PCDHA123	PCDHA123_2_gene	HARS2	-0.194	0.0302	0.0475	0.41
rs324015	STAT6	STAT6_3_gene	STAT6	0.24	0.0358	0.047	0.41
rs2027349	VPS45	VPS45_1_gene	VPS45	-0.302	0.0304	0.0462	0.41
rs12895055	BCL11B	BCL11B_3_gene	SETD3	-0.246	0.0335	0.0488	0.411
rs10933	PBRM1	PBRM1_2_gene	SFMBT1	-0.402	0.0341	0.0505	0.417
rs2027349	VPS45	VPS45_3_gene	SV2A	-0.361	0.04	0.0509	0.417
rs12895055	BCL11B	BCL11B_1_gene	SETD3	-0.253	0.0368	0.0558	0.451
rs324017	NAB2	NAB2_3_gene	MBD6	-0.262	0.041	0.059	0.458
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA6	0.19	0.0469	0.0595	0.458
rs301791	RERE	RERE_1_gene	ENO1	0.0953	0.0399	0.0586	0.458
rs324015	STAT6	STAT6_1_gene	PTGES3	0.1	0.0458	0.0595	0.458
rs7148456	BAG5	BAG5_3_gene	TRMT61A	0.302	0.052	0.0671	0.464
rs520843	GALNT10	GALNT10_1_gene	FAM114A2	-0.164	0.0532	0.065	0.464
rs12716973	KCTD13	KCTD13_2_gene	ALDOA	-0.256	0.0489	0.0667	0.464
rs186132169	NGEF	NGEF_2_gene	ECEL1	0.728	0.043	0.0645	0.464
rs186132169	NGEF	NGEF_3_gene	EIF4E2	0.296	0.0411	0.0611	0.464
rs10933	PBRM1	PBRM1_2_gene	TWF2	0.269	0.0468	0.0649	0.464
rs4151680	PCDHA123	PCDHA123_1_gene	HBEGF	0.229	0.0498	0.0627	0.464
rs324015	STAT6	STAT6_1_gene	MARS	0.162	0.049	0.0628	0.464
rs324015	STAT6	STAT6_2_gene	DDIT3	0.192	0.05	0.0657	0.464
rs9661794	DPYD	DPYD_1_gene	MIR137HG	-0.211	0.0488	0.0679	0.464
rs520843	GALNT10	GALNT10_3_gene	MFAP3	-0.198	0.0476	0.0697	0.468
rs3861678	LINC00637	LINC00637_3_gene	ZFYVE21	-0.142	0.0524	0.07	0.468
rs7148456	BAG5	BAG5_2_gene	APOPT1	-0.108	0.0531	0.0731	0.474
rs10933	PBRM1	PBRM1_1_gene	GNL3	0.246	0.0589	0.0732	0.474
rs2027349	VPS45	VPS45_1_gene	PLEKHO1	0.195	0.055	0.073	0.474
rs7170068	CHRNA3	CHRNA3_1_gene	CRABP1	0.693	0.062	0.08	0.475
rs324017	NAB2	NAB2_1_gene	NDUFA4L2	-0.223	0.0629	0.0779	0.475
rs324017	NAB2	NAB2_2_gene	MBD6	0.27	0.0621	0.0808	0.475
rs10933	PBRM1	PBRM1_1_gene	GLT8D1	0.253	0.0657	0.08	0.475
rs324015	STAT6	STAT6_3_gene	MARS	0.142	0.0677	0.0787	0.475
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ZNF592	0.355	0.0686	0.08	0.475
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	PDE8A	0.376	0.0525	0.0786	0.475
rs2027349	VPS45	VPS45_1_gene	CA14	0.381	0.0626	0.081	0.475
rs2027349	VPS45	VPS45_2_gene	PLEKHO1	0.0882	0.0618	0.0776	0.475
rs2027349	VPS45	VPS45_3_gene	SF3B4	0.193	0.0683	0.079	0.475
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA10	-0.145	0.066	0.0838	0.476
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB10	0.145	0.067	0.0847	0.476
rs324015	STAT6	STAT6_1_gene	PRIM1	-0.23	0.0709	0.0854	0.476
rs324015	STAT6	STAT6_2_gene	NAB2	0.181	0.0689	0.0848	0.476
rs2027349	VPS45	VPS45_3_gene	C1orf54	0.337	0.0753	0.0859	0.476
rs2027349	VPS45	VPS45_3_gene	RPRD2	0.262	0.0717	0.0824	0.476
rs7170068	CHRNA3	CHRNA3_1_gene	CHRNA3	0.51	0.07	0.0883	0.477
rs7170068	CHRNA3	CHRNA3_3_gene	DNAJA4	0.362	0.0677	0.0911	0.477
rs12716973	KCTD13	KCTD13_2_gene	MVP	-0.28	0.0709	0.09	0.477
rs324017	NAB2	NAB2_1_gene	SHMT2	-0.18	0.0751	0.0901	0.477
rs10933	PBRM1	PBRM1_3_gene	GLYCTK	-0.4	0.0747	0.0888	0.477
rs324015	STAT6	STAT6_2_gene	R3HDM2	-0.143	0.0754	0.0916	0.477
rs2027349	VPS45	VPS45_1_gene	ANP32E	0.291	0.0716	0.0903	0.477
rs9882911	TRANK1	TRANK1_1_gene	MLH1	-1.06	0.0668	0.0948	0.49
rs7170068	CHRNA3	CHRNA3_2_gene	CTSH	-0.263	0.0778	0.0988	0.498
rs6071578	PPP1R16B	PPP1R16B_1_gene	FAM83D	0.197	0.0843	0.0976	0.498
rs6071578	PPP1R16B	PPP1R16B_3_gene	SLC32A1	-0.263	0.0767	0.0982	0.498
rs7148456	BAG5	BAG5_1_gene	TRMT61A	-0.19	0.0797	0.104	0.502
rs520843	GALNT10	GALNT10_3_gene	LARP1	-0.0982	0.0753	0.1	0.502
rs3861678	LINC00637	LINC00637_2_gene	ZFYVE21	-0.151	0.0838	0.103	0.502
rs4151680	PCDHA123	PCDHA123_2_gene	WDR55	-0.153	0.0831	0.105	0.502
rs301791	RERE	RERE_2_gene	PARK7	0.0705	0.0754	0.103	0.502
rs9882911	TRANK1	TRANK1_2_gene	MLH1	0.199	0.0978	0.101	0.502
rs2027349	VPS45	VPS45_1_gene	RPRD2	0.244	0.085	0.104	0.502
rs2027349	VPS45	VPS45_2_gene	CIART	0.141	0.0909	0.107	0.506
rs9661794	DPYD	DPYD_2_gene	MIR137HG	-0.137	0.0948	0.108	0.507
rs12716973	KCTD13	KCTD13_2_gene	MAPK3	0.194	0.0898	0.11	0.511
rs3861678	LINC00637	LINC00637_1_gene	PPP1R13B	0.18	0.0912	0.113	0.521
rs3861678	LINC00637	LINC00637_2_gene	APOPT1	-0.104	0.0945	0.114	0.521
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB14	0.144	0.0948	0.114	0.521
rs2027349	VPS45	VPS45_3_gene	APH1A	0.189	0.107	0.116	0.526
rs7170068	CHRNA3	CHRNA3_2_gene	CRABP1	-0.4	0.103	0.124	0.526
rs520843	GALNT10	GALNT10_2_gene	FAM114A2	-0.165	0.0847	0.122	0.526
rs12716973	KCTD13	KCTD13_1_gene	PPP4C	-0.106	0.0948	0.123	0.526
rs12716973	KCTD13	KCTD13_2_gene	PRRT2	0.278	0.0987	0.119	0.526
rs324017	NAB2	NAB2_3_gene	R3HDM2	-0.165	0.0985	0.119	0.526
rs186132169	NGEF	NGEF_1_gene	EIF4E2	0.198	0.109	0.124	0.526
rs10933	PBRM1	PBRM1_2_gene	SPCS1	0.129	0.0979	0.119	0.526
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA10	0.136	0.1	0.123	0.526
rs324015	STAT6	STAT6_3_gene	NXPH4	0.212	0.114	0.123	0.526
rs2027349	VPS45	VPS45_1_gene	MRPS21	0.12	0.107	0.126	0.531
rs7170068	CHRNA3	CHRNA3_2_gene	IREB2	-0.174	0.107	0.128	0.536
rs12716973	KCTD13	KCTD13_1_gene	ZNF771	-0.163	0.102	0.13	0.536
rs324015	STAT6	STAT6_1_gene	BAZ2A	0.142	0.116	0.13	0.536
rs324017	NAB2	NAB2_3_gene	DDIT3	-0.203	0.112	0.133	0.538
rs6071578	PPP1R16B	PPP1R16B_2_gene	RALGAPB	0.147	0.122	0.131	0.538
rs9882911	TRANK1	TRANK1_2_gene	EPM2AIP1	0.147	0.13	0.132	0.538
rs7148456	BAG5	BAG5_2_gene	ZFYVE21	-0.123	0.113	0.136	0.546
rs7148456	BAG5	BAG5_3_gene	CKB	0.166	0.127	0.143	0.554
rs3861678	LINC00637	LINC00637_3_gene	CKB	-0.0976	0.124	0.143	0.554
rs10933	PBRM1	PBRM1_1_gene	WDR82	0.172	0.128	0.14	0.554
rs4151680	PCDHA123	PCDHA123_3_gene	ZMAT2	0.0671	0.121	0.14	0.554
rs9882911	TRANK1	TRANK1_1_gene	EPM2AIP1	0.568	0.108	0.144	0.554
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ZSCAN2	-0.324	0.11	0.142	0.554
rs2027349	VPS45	VPS45_3_gene	ECM1	-0.341	0.135	0.144	0.554
rs10933	PBRM1	PBRM1_1_gene	SPCS1	0.123	0.133	0.145	0.554
rs186132169	NGEF	NGEF_2_gene	GIGYF2	-0.331	0.122	0.147	0.559
rs12716973	KCTD13	KCTD13_3_gene	MVP	0.34	0.135	0.151	0.564
rs324017	NAB2	NAB2_1_gene	ZBTB39	-0.199	0.137	0.152	0.564
rs4151680	PCDHA123	PCDHA123_1_gene	SRA1	0.0963	0.138	0.152	0.564
rs4151680	PCDHA123	PCDHA123_3_gene	HARS	0.064	0.134	0.153	0.564
rs324015	STAT6	STAT6_2_gene	LRP1	0.135	0.138	0.153	0.564
rs7148456	BAG5	BAG5_2_gene	CKB	-0.0973	0.144	0.167	0.567
rs7148456	BAG5	BAG5_3_gene	BAG5	0.173	0.142	0.158	0.567
rs12895055	BCL11B	BCL11B_2_gene	SETD3	-0.112	0.137	0.169	0.567
rs7170068	CHRNA3	CHRNA3_1_gene	DNAJA4	0.274	0.153	0.171	0.567
rs12716973	KCTD13	KCTD13_2_gene	TAOK2	-0.234	0.142	0.163	0.567
rs2192932	KMT2E	KMT2E_2_gene	SRPK2	-0.0978	0.141	0.16	0.567
rs3861678	LINC00637	LINC00637_1_gene	KLC1	-0.0986	0.141	0.163	0.567
rs3861678	LINC00637	LINC00637_2_gene	KLC1	-0.103	0.152	0.171	0.567
rs3861678	LINC00637	LINC00637_3_gene	KLC1	-0.0873	0.151	0.169	0.567
rs324017	NAB2	NAB2_1_gene	BAZ2A	-0.125	0.152	0.167	0.567
rs186132169	NGEF	NGEF_2_gene	EFHD1	0.448	0.141	0.166	0.567
rs10933	PBRM1	PBRM1_3_gene	SFMBT1	-0.296	0.149	0.162	0.567
rs10933	PBRM1	PBRM1_3_gene	WDR82	0.165	0.157	0.171	0.567
rs4151680	PCDHA123	PCDHA123_1_gene	IK	0.0654	0.153	0.166	0.567
rs4151680	PCDHA123	PCDHA123_2_gene	APBB3	0.117	0.135	0.158	0.567
rs324015	STAT6	STAT6_3_gene	PTGES3	0.0656	0.156	0.164	0.567
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	WDR73	0.215	0.159	0.168	0.567
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ALPK3	0.252	0.133	0.157	0.567
rs2027349	VPS45	VPS45_1_gene	TARS2	0.219	0.139	0.158	0.567
rs520843	GALNT10	GALNT10_3_gene	GALNT10	-0.137	0.148	0.176	0.578
rs186132169	NGEF	NGEF_3_gene	ECEL1	0.413	0.153	0.18	0.589
rs7170068	CHRNA3	CHRNA3_2_gene	WDR61	-0.124	0.168	0.19	0.593
rs12716973	KCTD13	KCTD13_1_gene	ASPHD1	0.18	0.153	0.184	0.593
rs12716973	KCTD13	KCTD13_1_gene	QPRT	-0.142	0.155	0.185	0.593
rs12716973	KCTD13	KCTD13_3_gene	PPP4C	-0.147	0.175	0.191	0.593
rs186132169	NGEF	NGEF_1_gene	ATG16L1	0.242	0.175	0.189	0.593
rs10933	PBRM1	PBRM1_2_gene	SMIM4	0.207	0.163	0.184	0.593
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA12	0.122	0.177	0.191	0.593
rs4151680	PCDHA123	PCDHA123_2_gene	SLC35A4	-0.0981	0.167	0.19	0.593
rs324015	STAT6	STAT6_3_gene	NAB2	0.145	0.177	0.184	0.593
rs2027349	VPS45	VPS45_1_gene	APH1A	0.162	0.168	0.186	0.593
rs12895055	BCL11B	BCL11B_3_gene	CYP46A1	-0.205	0.176	0.197	0.605
rs324015	STAT6	STAT6_1_gene	PIP4K2C	0.148	0.187	0.199	0.605
rs324015	STAT6	STAT6_1_gene	R3HDM2	0.12	0.185	0.196	0.605
rs2027349	VPS45	VPS45_2_gene	SF3B4	0.0656	0.185	0.199	0.605
rs7170068	CHRNA3	CHRNA3_2_gene	CHRNA5	-0.197	0.185	0.208	0.606
rs12716973	KCTD13	KCTD13_1_gene	TMEM219	-0.101	0.175	0.206	0.606
rs12716973	KCTD13	KCTD13_3_gene	DOC2A	-0.256	0.192	0.207	0.606
rs324017	NAB2	NAB2_1_gene	PTGES3	-0.0617	0.194	0.208	0.606
rs324017	NAB2	NAB2_3_gene	NAB2	0.18	0.186	0.206	0.606
rs4151680	PCDHA123	PCDHA123_1_gene	ANKHD1	-0.125	0.189	0.202	0.606
rs324015	STAT6	STAT6_2_gene	SHMT2	0.12	0.191	0.205	0.606
rs324015	STAT6	STAT6_3_gene	KIF5A	0.138	0.199	0.205	0.606
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	NMB	0.235	0.195	0.203	0.606
rs7148456	BAG5	BAG5_3_gene	APOPT1	-0.114	0.195	0.209	0.607
rs4151680	PCDHA123	PCDHA123_1_gene	ZMAT2	0.0731	0.198	0.211	0.607
rs6071578	PPP1R16B	PPP1R16B_1_gene	RALGAPB	0.114	0.199	0.21	0.607
rs3861678	LINC00637	LINC00637_1_gene	MARK3	-0.0795	0.19	0.212	0.607
rs7170068	CHRNA3	CHRNA3_1_gene	MORF4L1	-0.0791	0.198	0.215	0.611
rs7148456	BAG5	BAG5_3_gene	EIF5	-0.1	0.202	0.216	0.612
rs324015	STAT6	STAT6_1_gene	LRP1	0.132	0.207	0.218	0.613
rs324015	STAT6	STAT6_2_gene	DCTN2	0.0513	0.205	0.218	0.613
rs324017	NAB2	NAB2_1_gene	PRIM1	0.149	0.208	0.221	0.618
rs7170068	CHRNA3	CHRNA3_3_gene	PSMA4	-0.107	0.196	0.224	0.623
rs10933	PBRM1	PBRM1_3_gene	ALAS1	-0.199	0.217	0.228	0.632
rs520843	GALNT10	GALNT10_3_gene	FAM114A2	-0.0989	0.202	0.23	0.636
rs324017	NAB2	NAB2_3_gene	PTGES3	-0.0701	0.216	0.236	0.648
rs6071578	PPP1R16B	PPP1R16B_1_gene	SNHG11	0.104	0.226	0.237	0.649
rs7170068	CHRNA3	CHRNA3_2_gene	MORF4L1	-0.0574	0.221	0.242	0.658
rs7148456	BAG5	BAG5_1_gene	EIF5	-0.0732	0.216	0.243	0.659
rs10933	PBRM1	PBRM1_3_gene	NISCH	-0.195	0.234	0.245	0.66
rs12716973	KCTD13	KCTD13_2_gene	INO80E	-0.146	0.229	0.248	0.664
rs2027349	VPS45	VPS45_2_gene	HIST2H2BE	0.103	0.236	0.248	0.664
rs12716973	KCTD13	KCTD13_3_gene	YPEL3	-0.193	0.236	0.251	0.666
rs186132169	NGEF	NGEF_1_gene	EFHD1	0.23	0.239	0.251	0.666
rs324015	STAT6	STAT6_2_gene	ZBTB39	0.125	0.242	0.253	0.667
rs12716973	KCTD13	KCTD13_1_gene	SEPT1	0.142	0.224	0.255	0.669
rs2027349	VPS45	VPS45_1_gene	ECM1	0.243	0.238	0.255	0.669
rs7148456	BAG5	BAG5_2_gene	KLC1	0.0774	0.236	0.257	0.67
rs324017	NAB2	NAB2_2_gene	PRIM1	-0.162	0.239	0.26	0.674
rs12716973	KCTD13	KCTD13_1_gene	MAZ	-0.0617	0.232	0.263	0.675
rs10933	PBRM1	PBRM1_2_gene	PHF7	0.222	0.243	0.262	0.675
rs2027349	VPS45	VPS45_1_gene	HIST2H2AC	0.226	0.246	0.262	0.675
rs7170068	CHRNA3	CHRNA3_1_gene	IREB2	-0.165	0.25	0.265	0.677
rs12895055	BCL11B	BCL11B_3_gene	CCNK	0.14	0.25	0.27	0.68
rs520843	GALNT10	GALNT10_2_gene	SAP30L	-0.128	0.226	0.271	0.68
rs12716973	KCTD13	KCTD13_3_gene	MAPK3	-0.164	0.255	0.27	0.68
rs2027349	VPS45	VPS45_2_gene	CA14	0.112	0.256	0.268	0.68
rs12716973	KCTD13	KCTD13_3_gene	CD2BP2	-0.176	0.259	0.273	0.682
rs12895055	BCL11B	BCL11B_1_gene	CCNK	0.144	0.256	0.28	0.683
rs12716973	KCTD13	KCTD13_1_gene	FAM57B	0.138	0.257	0.287	0.683
rs12716973	KCTD13	KCTD13_2_gene	CORO1A	-0.156	0.281	0.299	0.683
rs2192932	KMT2E	KMT2E_1_gene	SRPK2	-0.137	0.267	0.294	0.683
rs324017	NAB2	NAB2_1_gene	RBMS2	-0.138	0.277	0.288	0.683
rs324017	NAB2	NAB2_2_gene	KIF5A	0.158	0.256	0.276	0.683
rs324017	NAB2	NAB2_2_gene	MARS	-0.102	0.278	0.297	0.683
rs324017	NAB2	NAB2_2_gene	NAB2	-0.145	0.269	0.289	0.683
rs324017	NAB2	NAB2_2_gene	NACA	-0.0503	0.274	0.294	0.683
rs324017	NAB2	NAB2_2_gene	STAT6	0.166	0.28	0.3	0.683
rs186132169	NGEF	NGEF_1_gene	TIGD1	-0.205	0.288	0.299	0.683
rs10933	PBRM1	PBRM1_1_gene	NISCH	0.159	0.292	0.3	0.683
rs10933	PBRM1	PBRM1_2_gene	NT5DC2	0.13	0.274	0.292	0.683
rs10933	PBRM1	PBRM1_3_gene	NT5DC2	-0.139	0.289	0.298	0.683
rs6071578	PPP1R16B	PPP1R16B_2_gene	ACTR5	0.137	0.278	0.281	0.683
rs6071578	PPP1R16B	PPP1R16B_3_gene	ACTR5	0.12	0.275	0.297	0.683
rs301791	RERE	RERE_2_gene	ENO1	0.0705	0.267	0.296	0.683
rs324015	STAT6	STAT6_1_gene	DDIT3	0.123	0.28	0.29	0.683
rs324015	STAT6	STAT6_1_gene	SHMT2	0.116	0.278	0.287	0.683
rs324015	STAT6	STAT6_2_gene	KIF5A	-0.115	0.278	0.288	0.683
rs324015	STAT6	STAT6_2_gene	NXPH4	-0.145	0.275	0.285	0.683
rs324015	STAT6	STAT6_3_gene	TAC3	0.178	0.28	0.283	0.683
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	WDR73	0.14	0.269	0.29	0.683
rs2027349	VPS45	VPS45_3_gene	TARS2	-0.175	0.278	0.282	0.683
rs7170068	CHRNA3	CHRNA3_3_gene	IDH3A	0.165	0.282	0.309	0.685
rs12716973	KCTD13	KCTD13_2_gene	CD2BP2	-0.126	0.287	0.304	0.685
rs12716973	KCTD13	KCTD13_3_gene	KIF22	0.219	0.295	0.308	0.685
rs7936858	LOC100507431	LOC100507431_2_gene	SNX19	-0.148	0.296	0.308	0.685
rs4151680	PCDHA123	PCDHA123_3_gene	HARS2	-0.0783	0.292	0.307	0.685
rs324015	STAT6	STAT6_3_gene	PRIM1	-0.116	0.306	0.308	0.685
rs9882911	TRANK1	TRANK1_3_gene	MLH1	0.0679	0.287	0.304	0.685
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB14	-0.088	0.293	0.312	0.689
rs2027349	VPS45	VPS45_2_gene	RPRD2	-0.0706	0.308	0.318	0.7
rs2192932	KMT2E	KMT2E_3_gene	SRPK2	0.0687	0.313	0.322	0.705
rs17200916	LOC105376975	LOC105376975_2_gene	TBC1D5	-0.0775	0.296	0.323	0.705
rs186132169	NGEF	NGEF_3_gene	GIGYF2	0.154	0.297	0.322	0.705
rs10933	PBRM1	PBRM1_1_gene	TNNC1	-0.237	0.318	0.324	0.705
rs7148456	BAG5	BAG5_3_gene	XRCC3	0.173	0.322	0.332	0.713
rs10933	PBRM1	PBRM1_1_gene	GLYCTK	0.175	0.326	0.331	0.713
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ZNF592	0.15	0.311	0.33	0.713
rs4151680	PCDHA123	PCDHA123_1_gene	SLC35A4	0.0812	0.325	0.335	0.718
rs324015	STAT6	STAT6_3_gene	NACA	0.0359	0.339	0.339	0.724
rs324015	STAT6	STAT6_3_gene	BAZ2A	0.0802	0.342	0.342	0.729
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB15	-0.0749	0.328	0.346	0.729
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB5	0.113	0.328	0.346	0.729
rs6071578	PPP1R16B	PPP1R16B_2_gene	DHX35	0.12	0.345	0.344	0.729
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB2	0.0712	0.33	0.349	0.732
rs3861678	LINC00637	LINC00637_2_gene	CKB	0.0725	0.348	0.36	0.741
rs10933	PBRM1	PBRM1_2_gene	BAP1	0.151	0.341	0.357	0.741
rs10933	PBRM1	PBRM1_2_gene	NEK4	0.159	0.342	0.358	0.741
rs4151680	PCDHA123	PCDHA123_1_gene	HARS2	0.0976	0.351	0.36	0.741
rs324015	STAT6	STAT6_1_gene	NXPH4	0.138	0.351	0.359	0.741
rs324015	STAT6	STAT6_3_gene	PIP4K2C	0.0974	0.359	0.359	0.741
rs520843	GALNT10	GALNT10_2_gene	GRIA1	-0.12	0.325	0.367	0.743
rs3861678	LINC00637	LINC00637_1_gene	TRMT61A	-0.0872	0.349	0.367	0.743
rs324017	NAB2	NAB2_1_gene	LRP1	-0.0931	0.357	0.365	0.743
rs186132169	NGEF	NGEF_1_gene	ECEL1	-0.246	0.358	0.366	0.743
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	PDE8A	0.172	0.348	0.366	0.743
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB5	-0.0976	0.361	0.37	0.746
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA12	0.0709	0.365	0.382	0.768
rs186132169	NGEF	NGEF_3_gene	DGKD	-0.198	0.362	0.384	0.768
rs7148456	BAG5	BAG5_2_gene	EIF5	-0.0446	0.371	0.387	0.77
rs324017	NAB2	NAB2_3_gene	STAT6	-0.107	0.369	0.386	0.77
rs10933	PBRM1	PBRM1_2_gene	WDR82	0.0969	0.374	0.388	0.771
rs9882911	TRANK1	TRANK1_1_gene	GOLGA4	0.314	0.364	0.391	0.773
rs301791	RERE	RERE_3_gene	SLC45A1	-0.113	0.395	0.394	0.776
rs7170068	CHRNA3	CHRNA3_3_gene	CIB2	-0.106	0.374	0.398	0.782
rs7148456	BAG5	BAG5_1_gene	MARK3	-0.0606	0.38	0.402	0.782
rs7148456	BAG5	BAG5_3_gene	PPP1R13B	-0.132	0.395	0.402	0.782
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	SEC11A	0.0845	0.398	0.401	0.782
rs12895055	BCL11B	BCL11B_2_gene	CCNK	0.0673	0.386	0.412	0.787
rs12895055	BCL11B	BCL11B_3_gene	CCDC85C	0.139	0.396	0.412	0.787
rs7170068	CHRNA3	CHRNA3_3_gene	IREB2	0.11	0.4	0.421	0.787
rs9661794	DPYD	DPYD_3_gene	MIR137HG	0.111	0.405	0.41	0.787
rs520843	GALNT10	GALNT10_1_gene	LARP1	-0.049	0.424	0.424	0.787
rs12716973	KCTD13	KCTD13_2_gene	CDIPT	-0.0928	0.408	0.419	0.787
rs12716973	KCTD13	KCTD13_2_gene	SEPT1	-0.115	0.414	0.425	0.787
rs12716973	KCTD13	KCTD13_3_gene	SEPT1	0.167	0.414	0.423	0.787
rs324017	NAB2	NAB2_3_gene	LRP1	-0.1	0.393	0.409	0.787
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB2	0.0726	0.407	0.415	0.787
rs4151680	PCDHA123	PCDHA123_1_gene	WDR55	0.0778	0.416	0.424	0.787
rs4151680	PCDHA123	PCDHA123_2_gene	IK	0.0323	0.399	0.414	0.787
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA6	0.0666	0.409	0.423	0.787
rs324015	STAT6	STAT6_2_gene	MBD6	-0.103	0.405	0.411	0.787
rs2027349	VPS45	VPS45_2_gene	BOLA1	0.078	0.414	0.421	0.787
rs2027349	VPS45	VPS45_3_gene	BOLA1	0.19	0.42	0.419	0.787
rs7148456	BAG5	BAG5_3_gene	MARK3	-0.0745	0.421	0.427	0.787
rs12716973	KCTD13	KCTD13_3_gene	ZNF771	-0.142	0.418	0.426	0.787
rs520843	GALNT10	GALNT10_1_gene	SAP30L	-0.0712	0.434	0.434	0.791
rs12716973	KCTD13	KCTD13_3_gene	CDIPT	-0.118	0.426	0.435	0.791
rs12716973	KCTD13	KCTD13_3_gene	FAM57B	0.167	0.425	0.433	0.791
rs9882911	TRANK1	TRANK1_2_gene	GOLGA4	0.072	0.446	0.436	0.791
rs2027349	VPS45	VPS45_2_gene	PRPF3	0.0576	0.428	0.435	0.791
rs7170068	CHRNA3	CHRNA3_1_gene	CTSH	-0.151	0.431	0.44	0.794
rs186132169	NGEF	NGEF_3_gene	ATG16L1	-0.181	0.42	0.44	0.794
rs324017	NAB2	NAB2_2_gene	ZBTB39	0.114	0.428	0.443	0.797
rs3861678	LINC00637	LINC00637_1_gene	ZFYVE21	-0.0637	0.437	0.451	0.809
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB16	-0.0706	0.44	0.453	0.811
rs3861678	LINC00637	LINC00637_3_gene	XRCC3	-0.0612	0.452	0.459	0.819
rs2027349	VPS45	VPS45_3_gene	PRPF3	0.113	0.469	0.466	0.829
rs7170068	CHRNA3	CHRNA3_1_gene	CHRNA5	-0.153	0.462	0.47	0.831
rs12716973	KCTD13	KCTD13_3_gene	ZNF48	-0.123	0.462	0.469	0.831
rs7170068	CHRNA3	CHRNA3_3_gene	CRABP1	-0.217	0.457	0.476	0.839
rs7170068	CHRNA3	CHRNA3_3_gene	CHRNA5	-0.133	0.464	0.483	0.844
rs12716973	KCTD13	KCTD13_1_gene	DOC2A	0.0824	0.459	0.484	0.844
rs12716973	KCTD13	KCTD13_2_gene	QPRT	-0.0921	0.476	0.485	0.844
rs324017	NAB2	NAB2_3_gene	NDUFA4L2	-0.16	0.47	0.482	0.844
rs324017	NAB2	NAB2_3_gene	RBMS2	-0.123	0.473	0.486	0.844
rs301791	RERE	RERE_2_gene	SLC45A1	-0.0858	0.468	0.488	0.845
rs7148456	BAG5	BAG5_3_gene	ZFYVE21	-0.083	0.494	0.497	0.852
rs324017	NAB2	NAB2_2_gene	SHMT2	-0.0837	0.481	0.495	0.852
rs301791	RERE	RERE_3_gene	RERE	-0.0493	0.502	0.496	0.852
rs9882911	TRANK1	TRANK1_2_gene	STAC	0.0859	0.507	0.494	0.852
rs12716973	KCTD13	KCTD13_2_gene	PPP4C	0.0577	0.491	0.499	0.852
rs12716973	KCTD13	KCTD13_3_gene	BOLA2B	0.178	0.497	0.503	0.856
rs301791	RERE	RERE_3_gene	TNFRSF9	0.113	0.511	0.505	0.858
rs12716973	KCTD13	KCTD13_1_gene	CD2BP2	-0.064	0.485	0.508	0.859
rs12716973	KCTD13	KCTD13_2_gene	BOLA2B	-0.0949	0.501	0.508	0.859
rs3861678	LINC00637	LINC00637_1_gene	BAG5	-0.0507	0.498	0.51	0.86
rs520843	GALNT10	GALNT10_1_gene	MFAP3	0.0751	0.518	0.515	0.865
rs2027349	VPS45	VPS45_3_gene	PLEKHO1	0.0663	0.521	0.516	0.865
rs520843	GALNT10	GALNT10_2_gene	LARP1	-0.0482	0.488	0.521	0.869
rs6071578	PPP1R16B	PPP1R16B_3_gene	DHX35	-0.101	0.511	0.522	0.869
rs324015	STAT6	STAT6_3_gene	LRP1	0.0628	0.528	0.523	0.869
rs12716973	KCTD13	KCTD13_3_gene	TAOK2	0.125	0.518	0.524	0.869
rs4151680	PCDHA123	PCDHA123_3_gene	SRA1	0.032	0.521	0.526	0.87
rs12716973	KCTD13	KCTD13_1_gene	YPEL3	0.0641	0.515	0.536	0.878
rs2192932	KMT2E	KMT2E_3_gene	KMT2E	0.042	0.536	0.537	0.878
rs324017	NAB2	NAB2_3_gene	TAC3	-0.142	0.522	0.533	0.878
rs324015	STAT6	STAT6_2_gene	PIP4K2C	-0.0985	0.535	0.535	0.878
rs324017	NAB2	NAB2_3_gene	NXPH4	-0.113	0.531	0.541	0.88
rs10933	PBRM1	PBRM1_1_gene	PBRM1	-0.0657	0.547	0.545	0.88
rs4151680	PCDHA123	PCDHA123_2_gene	NDUFA2	0.023	0.534	0.543	0.88
rs6071578	PPP1R16B	PPP1R16B_1_gene	DHX35	0.0459	0.546	0.545	0.88
rs2027349	VPS45	VPS45_1_gene	BOLA1	-0.166	0.536	0.541	0.88
rs186132169	NGEF	NGEF_1_gene	GIGYF2	0.0751	0.545	0.547	0.88
rs4151680	PCDHA123	PCDHA123_2_gene	HARS	0.029	0.541	0.549	0.882
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	GOLGA6L4	-0.13	0.533	0.553	0.886
rs520843	GALNT10	GALNT10_2_gene	GALNT10	0.0762	0.529	0.559	0.887
rs324015	STAT6	STAT6_3_gene	ZBTB39	-0.0958	0.563	0.556	0.887
rs9882911	TRANK1	TRANK1_2_gene	LRRFIP2	0.0585	0.574	0.56	0.887
rs2027349	VPS45	VPS45_1_gene	SF3B4	0.0628	0.554	0.559	0.887
rs12716973	KCTD13	KCTD13_2_gene	ASPHD1	-0.0882	0.564	0.569	0.89
rs12716973	KCTD13	KCTD13_3_gene	DCTPP1	-0.0792	0.567	0.57	0.89
rs3861678	LINC00637	LINC00637_3_gene	APOPT1	-0.0307	0.566	0.568	0.89
rs3861678	LINC00637	LINC00637_3_gene	BAG5	0.0396	0.564	0.566	0.89
rs186132169	NGEF	NGEF_2_gene	DGKD	0.159	0.557	0.566	0.89
rs10933	PBRM1	PBRM1_2_gene	GLT8D1	0.0785	0.559	0.566	0.89
rs324017	NAB2	NAB2_1_gene	PIP4K2C	-0.0635	0.573	0.573	0.892
rs324017	NAB2	NAB2_3_gene	DCTN2	-0.0305	0.566	0.575	0.892
rs7170068	CHRNA3	CHRNA3_2_gene	CIB2	-0.0587	0.577	0.582	0.897
rs10933	PBRM1	PBRM1_1_gene	RFT1	0.106	0.585	0.581	0.897
rs324015	STAT6	STAT6_3_gene	DCTN2	0.0236	0.587	0.579	0.897
rs520843	GALNT10	GALNT10_3_gene	SAP30L	0.0605	0.574	0.586	0.898
rs10933	PBRM1	PBRM1_3_gene	RFT1	-0.101	0.588	0.585	0.898
rs12716973	KCTD13	KCTD13_2_gene	DOC2A	-0.0852	0.587	0.591	0.901
rs324017	NAB2	NAB2_3_gene	PIP4K2C	0.0871	0.584	0.592	0.901
rs10933	PBRM1	PBRM1_3_gene	PRKCD	0.0801	0.592	0.589	0.901
rs12716973	KCTD13	KCTD13_1_gene	PRRT2	-0.0698	0.583	0.601	0.904
rs324017	NAB2	NAB2_1_gene	R3HDM2	0.0459	0.601	0.6	0.904
rs324015	STAT6	STAT6_2_gene	NDUFA4L2	-0.0404	0.603	0.601	0.904
rs9882911	TRANK1	TRANK1_1_gene	STAC	-0.379	0.585	0.598	0.904
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ALPK3	0.104	0.609	0.602	0.904
rs2027349	VPS45	VPS45_2_gene	TARS2	-0.0365	0.599	0.598	0.904
rs186132169	NGEF	NGEF_1_gene	DGKD	-0.0954	0.608	0.607	0.906
rs10933	PBRM1	PBRM1_1_gene	TWF2	0.0742	0.611	0.606	0.906
rs12895055	BCL11B	BCL11B_1_gene	CYP46A1	-0.0878	0.604	0.612	0.907
rs10933	PBRM1	PBRM1_3_gene	BAP1	0.0877	0.615	0.611	0.907
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ZSCAN2	0.0772	0.608	0.612	0.907
rs7170068	CHRNA3	CHRNA3_2_gene	IDH3A	-0.0639	0.618	0.621	0.916
rs324015	STAT6	STAT6_1_gene	ZBTB39	-0.0467	0.625	0.622	0.916
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	SEC11A	0.0521	0.608	0.623	0.916
rs12716973	KCTD13	KCTD13_3_gene	KCTD13	-0.0931	0.625	0.626	0.919
rs7148456	BAG5	BAG5_2_gene	TRMT61A	0.0425	0.639	0.642	0.922
rs7148456	BAG5	BAG5_3_gene	KLC1	0.0495	0.633	0.631	0.922
rs7170068	CHRNA3	CHRNA3_1_gene	ADAMTS7	0.121	0.652	0.65	0.922
rs12716973	KCTD13	KCTD13_1_gene	KCTD13	0.0577	0.622	0.636	0.922
rs12716973	KCTD13	KCTD13_2_gene	HIRIP3	0.0676	0.644	0.645	0.922
rs12716973	KCTD13	KCTD13_3_gene	CORO1A	0.0959	0.633	0.634	0.922
rs12716973	KCTD13	KCTD13_3_gene	TMEM219	0.0585	0.652	0.652	0.922
rs3861678	LINC00637	LINC00637_2_gene	TRMT61A	0.0459	0.651	0.65	0.922
rs1198588	miR137	miR137_3_gene	MIR137HG	-0.0548	0.647	0.649	0.922
rs324017	NAB2	NAB2_3_gene	KIF5A	0.0659	0.632	0.637	0.922
rs10933	PBRM1	PBRM1_1_gene	PRKCD	-0.0578	0.645	0.639	0.922
rs10933	PBRM1	PBRM1_2_gene	GLYCTK	0.0993	0.649	0.652	0.922
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB16	-0.0621	0.648	0.648	0.922
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB16	0.0415	0.644	0.644	0.922
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	GOLGA6L4	0.106	0.641	0.634	0.922
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	PDE8A	0.122	0.66	0.652	0.922
rs3861678	LINC00637	LINC00637_3_gene	TRMT61A	-0.0387	0.655	0.654	0.922
rs12716973	KCTD13	KCTD13_1_gene	INO80E	-0.0438	0.644	0.658	0.922
rs7936858	LOC100507431	LOC100507431_3_gene	SNX19	0.0517	0.657	0.656	0.922
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB15	-0.0273	0.66	0.658	0.922
rs7148456	BAG5	BAG5_1_gene	BAG5	0.037	0.668	0.674	0.922
rs7148456	BAG5	BAG5_1_gene	ZFYVE21	-0.0401	0.668	0.674	0.922
rs12895055	BCL11B	BCL11B_2_gene	CCDC85C	-0.0434	0.658	0.667	0.922
rs7170068	CHRNA3	CHRNA3_1_gene	IDH3A	-0.0731	0.663	0.662	0.922
rs12716973	KCTD13	KCTD13_1_gene	SEZ6L2	0.045	0.656	0.669	0.922
rs12716973	KCTD13	KCTD13_2_gene	TBC1D10B	-0.048	0.673	0.673	0.922
rs12716973	KCTD13	KCTD13_2_gene	YPEL3	-0.0518	0.677	0.676	0.922
rs12716973	KCTD13	KCTD13_3_gene	PRRT2	-0.0888	0.672	0.671	0.922
rs3861678	LINC00637	LINC00637_1_gene	CKB	-0.0311	0.66	0.663	0.922
rs10933	PBRM1	PBRM1_1_gene	PHF7	-0.0738	0.678	0.67	0.922
rs301791	RERE	RERE_1_gene	ERRFI1	-0.0309	0.675	0.676	0.922
rs324015	STAT6	STAT6_3_gene	NDUFA4L2	0.0367	0.679	0.67	0.922
rs2027349	VPS45	VPS45_1_gene	SV2A	-0.0659	0.689	0.687	0.935
rs7170068	CHRNA3	CHRNA3_3_gene	ADAMTS7	-0.103	0.685	0.691	0.936
rs3861678	LINC00637	LINC00637_3_gene	MARK3	-0.0214	0.694	0.691	0.936
rs301791	RERE	RERE_3_gene	PARK7	0.0169	0.704	0.693	0.937
rs7170068	CHRNA3	CHRNA3_3_gene	CTSH	0.0685	0.692	0.698	0.939
rs324015	STAT6	STAT6_3_gene	MBD6	-0.0647	0.708	0.698	0.939
rs520843	GALNT10	GALNT10_1_gene	GRIA1	-0.0413	0.711	0.701	0.94
rs324017	NAB2	NAB2_3_gene	MARS	-0.0371	0.699	0.701	0.94
rs10933	PBRM1	PBRM1_2_gene	GNL3	-0.0488	0.71	0.71	0.949
rs2192932	KMT2E	KMT2E_1_gene	KMT2E	-0.0467	0.708	0.712	0.95
rs324017	NAB2	NAB2_2_gene	DDIT3	-0.0482	0.715	0.717	0.954
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	WDR73	0.0591	0.71	0.718	0.954
rs10933	PBRM1	PBRM1_3_gene	GLT8D1	-0.0512	0.728	0.721	0.956
rs7170068	CHRNA3	CHRNA3_3_gene	WDR61	-0.0329	0.751	0.753	0.956
rs520843	GALNT10	GALNT10_3_gene	GRIA1	-0.0314	0.755	0.755	0.956
rs12716973	KCTD13	KCTD13_1_gene	CDIPT	-0.0295	0.746	0.752	0.956
rs12716973	KCTD13	KCTD13_1_gene	DCTPP1	-0.0267	0.742	0.748	0.956
rs12716973	KCTD13	KCTD13_1_gene	MVP	-0.0428	0.724	0.732	0.956
rs12716973	KCTD13	KCTD13_2_gene	KIF22	0.0495	0.744	0.741	0.956
rs12716973	KCTD13	KCTD13_2_gene	MAZ	0.0205	0.76	0.756	0.956
rs12716973	KCTD13	KCTD13_3_gene	INO80E	-0.0491	0.764	0.76	0.956
rs12716973	KCTD13	KCTD13_3_gene	QPRT	0.0527	0.764	0.76	0.956
rs2192932	KMT2E	KMT2E_1_gene	PUS7	0.0754	0.751	0.752	0.956
rs2192932	KMT2E	KMT2E_2_gene	KMT2E	-0.023	0.73	0.728	0.956
rs2192932	KMT2E	KMT2E_2_gene	PUS7	-0.0584	0.737	0.735	0.956
rs3861678	LINC00637	LINC00637_2_gene	BAG5	-0.0281	0.733	0.729	0.956
rs17200916	LOC105376975	LOC105376975_1_gene	TBC1D5	0.0286	0.769	0.759	0.956
rs324017	NAB2	NAB2_2_gene	LRP1	-0.0397	0.743	0.744	0.956
rs324017	NAB2	NAB2_2_gene	NXPH4	-0.0562	0.731	0.732	0.956
rs186132169	NGEF	NGEF_2_gene	TIGD1	-0.261	0.727	0.727	0.956
rs186132169	NGEF	NGEF_3_gene	TIGD1	-0.071	0.747	0.749	0.956
rs10933	PBRM1	PBRM1_1_gene	SFMBT1	-0.0645	0.753	0.743	0.956
rs10933	PBRM1	PBRM1_3_gene	TWF2	-0.0496	0.743	0.736	0.956
rs6071578	PPP1R16B	PPP1R16B_2_gene	SLC32A1	-0.0432	0.747	0.736	0.956
rs6071578	PPP1R16B	PPP1R16B_3_gene	RALGAPB	-0.0317	0.75	0.749	0.956
rs324015	STAT6	STAT6_1_gene	KIF5A	0.0366	0.759	0.752	0.956
rs324015	STAT6	STAT6_3_gene	R3HDM2	0.0268	0.74	0.729	0.956
rs9882911	TRANK1	TRANK1_3_gene	STAC	-0.011	0.752	0.748	0.956
rs324017	NAB2	NAB2_2_gene	PIP4K2C	0.0358	0.767	0.766	0.96
rs4151680	PCDHA123	PCDHA123_3_gene	SLC35A4	-0.018	0.771	0.765	0.96
rs12716973	KCTD13	KCTD13_1_gene	KIF22	-0.034	0.771	0.774	0.961
rs324017	NAB2	NAB2_2_gene	BAZ2A	-0.0303	0.77	0.769	0.961
rs10933	PBRM1	PBRM1_2_gene	RFT1	0.0476	0.784	0.779	0.961
rs4151680	PCDHA123	PCDHA123_2_gene	ANKHD1	0.0318	0.777	0.773	0.961
rs4151680	PCDHA123	PCDHA123_3_gene	IK	0.00946	0.787	0.78	0.961
rs301791	RERE	RERE_1_gene	SLC45A1	0.0248	0.785	0.782	0.961
rs301791	RERE	RERE_2_gene	RERE	0.0183	0.778	0.78	0.961
rs324015	STAT6	STAT6_1_gene	STAT6	0.0375	0.785	0.777	0.961
rs2027349	VPS45	VPS45_3_gene	MRPS21	-0.0207	0.786	0.775	0.961
rs7170068	CHRNA3	CHRNA3_1_gene	PSMA4	0.0255	0.791	0.784	0.961
rs7170068	CHRNA3	CHRNA3_3_gene	MORF4L1	-0.0147	0.787	0.787	0.961
rs12716973	KCTD13	KCTD13_1_gene	TAOK2	-0.0383	0.786	0.788	0.961
rs324015	STAT6	STAT6_1_gene	NAB2	0.0315	0.795	0.787	0.961
rs7148456	BAG5	BAG5_1_gene	APOPT1	0.0344	0.817	0.813	0.964
rs7148456	BAG5	BAG5_1_gene	CKB	-0.0187	0.815	0.811	0.964
rs7148456	BAG5	BAG5_2_gene	MARK3	0.0139	0.814	0.807	0.964
rs7170068	CHRNA3	CHRNA3_1_gene	CIB2	-0.0331	0.808	0.801	0.964
rs12716973	KCTD13	KCTD13_1_gene	MAPK3	0.0197	0.816	0.816	0.964
rs12716973	KCTD13	KCTD13_1_gene	TBC1D10B	-0.0202	0.819	0.818	0.964
rs12716973	KCTD13	KCTD13_2_gene	DCTPP1	0.0244	0.813	0.807	0.964
rs12716973	KCTD13	KCTD13_2_gene	FAM57B	0.0355	0.819	0.812	0.964
rs12716973	KCTD13	KCTD13_3_gene	TBC1D10B	0.0366	0.814	0.808	0.964
rs3861678	LINC00637	LINC00637_1_gene	APOPT1	-0.0138	0.813	0.808	0.964
rs324017	NAB2	NAB2_1_gene	MARS	-0.0181	0.823	0.813	0.964
rs324017	NAB2	NAB2_3_gene	BAZ2A	-0.0236	0.823	0.818	0.964
rs186132169	NGEF	NGEF_2_gene	ATG16L1	0.116	0.805	0.801	0.964
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA11	-0.0188	0.819	0.811	0.964
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB14	0.0277	0.809	0.801	0.964
rs301791	RERE	RERE_2_gene	TNFRSF9	0.0427	0.801	0.8	0.964
rs324015	STAT6	STAT6_3_gene	SHMT2	0.0256	0.804	0.793	0.964
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ALPK3	-0.0495	0.816	0.816	0.964
rs324015	STAT6	STAT6_2_gene	PRIM1	0.0245	0.833	0.823	0.966
rs2027349	VPS45	VPS45_1_gene	OTUD7B	-0.0329	0.831	0.823	0.966
rs520843	GALNT10	GALNT10_1_gene	GALNT10	-0.0174	0.851	0.839	0.972
rs12716973	KCTD13	KCTD13_1_gene	HIRIP3	-0.0222	0.842	0.839	0.972
rs7936858	LOC100507431	LOC100507431_1_gene	SNX19	-0.0295	0.843	0.835	0.972
rs324017	NAB2	NAB2_2_gene	DCTN2	-0.0106	0.842	0.837	0.972
rs324015	STAT6	STAT6_2_gene	BAZ2A	-0.0171	0.839	0.83	0.972
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ZNF592	-0.0348	0.834	0.833	0.972
rs2027349	VPS45	VPS45_1_gene	C1orf54	0.0385	0.846	0.837	0.972
rs12716973	KCTD13	KCTD13_2_gene	ZNF48	-0.0206	0.869	0.861	0.972
rs12716973	KCTD13	KCTD13_3_gene	ASPHD1	0.0395	0.852	0.845	0.972
rs3861678	LINC00637	LINC00637_3_gene	PPP1R13B	0.0189	0.874	0.863	0.972
rs324017	NAB2	NAB2_1_gene	NAB2	-0.0149	0.877	0.866	0.972
rs324017	NAB2	NAB2_2_gene	R3HDM2	0.018	0.864	0.858	0.972
rs324017	NAB2	NAB2_3_gene	SHMT2	-0.0214	0.865	0.859	0.972
rs186132169	NGEF	NGEF_2_gene	EIF4E2	-0.0342	0.868	0.861	0.972
rs10933	PBRM1	PBRM1_2_gene	NISCH	0.0269	0.855	0.847	0.972
rs10933	PBRM1	PBRM1_3_gene	SMIM4	-0.0273	0.876	0.865	0.972
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB15	-0.0218	0.871	0.862	0.972
rs4151680	PCDHA123	PCDHA123_2_gene	ZMAT2	0.00762	0.872	0.864	0.972
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB9	0.0272	0.856	0.847	0.972
rs6071578	PPP1R16B	PPP1R16B_2_gene	SNHG11	-0.0149	0.868	0.855	0.972
rs301791	RERE	RERE_3_gene	ERRFI1	-0.0216	0.855	0.842	0.972
rs9882911	TRANK1	TRANK1_3_gene	EPM2AIP1	-0.00903	0.859	0.85	0.972
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ZSCAN2	0.0379	0.875	0.862	0.972
rs2027349	VPS45	VPS45_1_gene	CIART	0.0135	0.865	0.856	0.972
rs12716973	KCTD13	KCTD13_1_gene	CORO1A	0.0165	0.873	0.868	0.972
rs12895055	BCL11B	BCL11B_1_gene	CCDC85C	-0.0216	0.882	0.874	0.976
rs324017	NAB2	NAB2_3_gene	PRIM1	0.0229	0.882	0.875	0.976
rs3861678	LINC00637	LINC00637_2_gene	XRCC3	-0.0365	0.887	0.877	0.977
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA10	0.0121	0.888	0.878	0.977
rs7148456	BAG5	BAG5_1_gene	KLC1	-0.00608	0.936	0.927	0.978
rs7148456	BAG5	BAG5_1_gene	PPP1R13B	0.00986	0.922	0.913	0.978
rs7170068	CHRNA3	CHRNA3_1_gene	WDR61	-0.0103	0.931	0.921	0.978
rs520843	GALNT10	GALNT10_2_gene	MFAP3	-0.0579	0.899	0.895	0.978
rs12716973	KCTD13	KCTD13_1_gene	BOLA2B	0.0237	0.928	0.92	0.978
rs12716973	KCTD13	KCTD13_2_gene	ZNF771	-0.0141	0.912	0.902	0.978
rs12716973	KCTD13	KCTD13_3_gene	SEZ6L2	-0.0211	0.905	0.895	0.978
rs2192932	KMT2E	KMT2E_3_gene	PUS7	0.0347	0.926	0.915	0.978
rs3861678	LINC00637	LINC00637_2_gene	MARK3	0.0077	0.907	0.897	0.978
rs17200916	LOC105376975	LOC105376975_3_gene	TBC1D5	0.00969	0.94	0.929	0.978
rs324017	NAB2	NAB2_1_gene	MBD6	-0.00842	0.93	0.918	0.978
rs324017	NAB2	NAB2_1_gene	NACA	0.00457	0.906	0.894	0.978
rs324017	NAB2	NAB2_1_gene	STAT6	0.0244	0.912	0.9	0.978
rs10933	PBRM1	PBRM1_1_gene	ALAS1	0.0174	0.91	0.897	0.978
rs10933	PBRM1	PBRM1_1_gene	BAP1	-0.0243	0.932	0.92	0.978
rs10933	PBRM1	PBRM1_1_gene	NEK4	-0.0192	0.926	0.914	0.978
rs10933	PBRM1	PBRM1_1_gene	SMIM4	0.0195	0.906	0.893	0.978
rs10933	PBRM1	PBRM1_2_gene	PRKCD	0.0385	0.927	0.917	0.978
rs10933	PBRM1	PBRM1_3_gene	PHF7	-0.0623	0.935	0.924	0.978
rs10933	PBRM1	PBRM1_3_gene	SPCS1	0.01	0.907	0.896	0.978
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB10	-0.0281	0.936	0.927	0.978
rs4151680	PCDHA123	PCDHA123_3_gene	ANKHD1	0.028	0.924	0.913	0.978
rs4151680	PCDHA123	PCDHA123_3_gene	NDUFA2	0.00262	0.938	0.928	0.978
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA11	0.00625	0.896	0.885	0.978
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB2	0.00761	0.9	0.89	0.978
rs301791	RERE	RERE_1_gene	RERE	0.00577	0.909	0.9	0.978
rs301791	RERE	RERE_2_gene	ERRFI1	-0.0119	0.91	0.903	0.978
rs301791	RERE	RERE_3_gene	ENO1	0.0052	0.942	0.93	0.978
rs324015	STAT6	STAT6_1_gene	MBD6	-0.00957	0.921	0.909	0.978
rs324015	STAT6	STAT6_2_gene	PTGES3	-0.00439	0.92	0.908	0.978
rs324015	STAT6	STAT6_3_gene	DDIT3	-0.014	0.908	0.896	0.978
rs2027349	VPS45	VPS45_1_gene	HIST2H2BE	0.0398	0.929	0.919	0.978
rs2027349	VPS45	VPS45_2_gene	OTUD7B	0.00512	0.942	0.932	0.978
rs7148456	BAG5	BAG5_2_gene	PPP1R13B	0.036	0.962	0.955	0.985
rs1198588	miR137	miR137_2_gene	MIR137HG	-0.0122	0.959	0.952	0.985
rs324017	NAB2	NAB2_1_gene	KIF5A	-0.0055	0.963	0.955	0.985
rs324017	NAB2	NAB2_3_gene	NACA	0.00246	0.957	0.95	0.985
rs324017	NAB2	NAB2_3_gene	ZBTB39	0.00418	0.964	0.957	0.985
rs10933	PBRM1	PBRM1_3_gene	NEK4	-0.0095	0.954	0.945	0.985
rs4151680	PCDHA123	PCDHA123_2_gene	SRA1	0.00213	0.966	0.959	0.985
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB5	0.0274	0.954	0.945	0.985
rs324015	STAT6	STAT6_2_gene	MARS	0.00438	0.954	0.945	0.985
rs9882911	TRANK1	TRANK1_1_gene	LRRFIP2	-0.0204	0.958	0.953	0.985
rs2027349	VPS45	VPS45_1_gene	PRPF3	0.00926	0.96	0.952	0.985
rs2027349	VPS45	VPS45_2_gene	HIST2H2AC	-0.00119	0.951	0.941	0.985
rs2027349	VPS45	VPS45_3_gene	OTUD7B	0.0427	0.966	0.958	0.985
rs3861678	LINC00637	LINC00637_1_gene	XRCC3	-0.00316	0.974	0.968	0.985
rs324017	NAB2	NAB2_1_gene	DDIT3	0.00441	0.969	0.961	0.985
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA4	-0.0374	0.974	0.968	0.985
rs6071578	PPP1R16B	PPP1R16B_3_gene	SNHG11	-0.00486	0.974	0.968	0.985
rs301791	RERE	RERE_1_gene	TNFRSF9	0.00612	0.971	0.965	0.985
rs324015	STAT6	STAT6_1_gene	NDUFA4L2	-0.0098	0.975	0.969	0.985
rs12895055	BCL11B	BCL11B_2_gene	CYP46A1	0.0028	0.982	0.978	0.988
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB9	-0.0048	0.982	0.978	0.988
rs6071578	PPP1R16B	PPP1R16B_1_gene	ACTR5	-0.00176	0.982	0.977	0.988
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	NMB	0.00774	0.979	0.974	0.988
rs12716973	KCTD13	KCTD13_3_gene	MAZ	-0.000705	0.994	0.992	0.996
rs10933	PBRM1	PBRM1_2_gene	ALAS1	-0.000644	0.994	0.992	0.996
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA11	0.0203	0.994	0.992	0.996
rs2027349	VPS45	VPS45_2_gene	SV2A	0.00054	0.992	0.99	0.996
rs6071578	PPP1R16B	PPP1R16B_2_gene	FAM83D	-0.00217	0.996	0.994	0.996
rs7170068	CHRNA3	CHRNA3_2_gene	ADAMTS7	0.00494	1	1	1

cis pairs that passed FDR < 0.1: 4 

cis pairs that have an empirical p values < 0.05: 73

---

1 Mb cis gene result

formatted.df = edgeR_cis_summary$cis_summary_1Mb
fdr_num = dim(filter(formatted.df, pval_adj_cis < 0.1))[1]
pval_num = dim(filter(formatted.df, empirical_pval < 0.05))[1]
formatted.df = select(formatted.df, c('SNP','locus','gRNA','gene','logFC','PValue',
                                        'empirical_pval','pval_adj_cis')) %>% arrange(pval_adj_cis)
formatted.df[,5:8] = signif(formatted.df[,5:8], digits = 3)
mutate(formatted.df, 
       logFC = cell_spec(logFC, "html", color = ifelse(logFC < 0, "red", "blue")),
       PValue = cell_spec(PValue, "html", color = ifelse(PValue < 0.05, "orange", "black")),
       empirical_pval = cell_spec(empirical_pval, "html", color = ifelse(empirical_pval < 0.05, "orange", "black")),
       pval_adj_cis = cell_spec(pval_adj_cis, "html", color = ifelse(pval_adj_cis < 0.1, "red", "black")) ) %>% 
  kable(format = "html", escape = F) %>%
  kable_styling() %>% scroll_box(width = "100%", height = "400px")

SNP	locus	gRNA	gene	logFC	PValue	empirical_pval	pval_adj_cis
rs324017	NAB2	NAB2_2_gene	TAC3	-1.85	1.05e-31	4.14e-06	0.00455
rs324015	STAT6	STAT6_2_gene	TAC3	1.46	7.13e-28	2.89e-05	0.0137
rs2027349	VPS45	VPS45_2_gene	VPS45	-0.627	1.43e-20	3.72e-05	0.0137
rs2027349	VPS45	VPS45_3_gene	VPS45	-0.874	2.66e-08	0.000215	0.0592
rs10933	PBRM1	PBRM1_3_gene	PBRM1	-0.512	1.71e-05	0.000881	0.194
rs4151680	PCDHA123	PCDHA123_2_gene	HBEGF	0.428	7.54e-06	0.00116	0.212
rs324015	STAT6	STAT6_2_gene	MYL6	0.254	2.27e-05	0.00139	0.218
rs324015	STAT6	STAT6_1_gene	MYL6	0.285	3.91e-05	0.00174	0.24
rs7148456	BAG5	BAG5_2_gene	BAG5	0.248	0.000898	0.00567	0.312
rs324017	NAB2	NAB2_2_gene	RBMS2	-0.425	0.000932	0.00561	0.312
rs10933	PBRM1	PBRM1_3_gene	GNL3	-0.494	0.00094	0.00476	0.312
rs10933	PBRM1	PBRM1_3_gene	POC1A	-0.82	0.00107	0.00507	0.312
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA4	-0.356	0.000313	0.0036	0.312
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA12	0.232	0.000718	0.00514	0.312
rs6071578	PPP1R16B	PPP1R16B_3_gene	FAM83D	-0.562	0.00015	0.00296	0.312
rs301791	RERE	RERE_2_gene	SPSB1	0.441	7.96e-05	0.00287	0.312
rs324015	STAT6	STAT6_2_gene	NACA	0.126	0.000307	0.00338	0.312
rs2027349	VPS45	VPS45_2_gene	ECM1	0.329	0.000504	0.0045	0.312
rs2027349	VPS45	VPS45_3_gene	HIST2H2AC	-0.745	0.0012	0.00534	0.312
rs2027349	VPS45	VPS45_3_gene	HIST2H2BE	-0.68	0.00126	0.00546	0.312
rs324015	STAT6	STAT6_1_gene	TAC3	-0.646	0.0017	0.00697	0.334
rs324015	STAT6	STAT6_1_gene	TSFM	0.266	0.0016	0.00674	0.334
rs324015	STAT6	STAT6_2_gene	STAT6	0.303	0.00148	0.00687	0.334
rs7170068	CHRNA3	CHRNA3_2_gene	TBC1D2B	-0.404	0.00462	0.0131	0.353
rs7170068	CHRNA3	CHRNA3_3_gene	CHRNA3	0.73	0.00444	0.0134	0.353
rs3861678	LINC00637	LINC00637_3_gene	CDC42BPB	-0.187	0.00332	0.0105	0.353
rs7936858	LOC100507431	LOC100507431_3_gene	NTM	-0.329	0.00221	0.00866	0.353
rs1198588	miR137	miR137_1_gene	MIR137HG	0.346	0.00237	0.00809	0.353
rs324017	NAB2	NAB2_1_gene	ESYT1	-0.291	0.00529	0.0133	0.353
rs324017	NAB2	NAB2_1_gene	TAC3	0.567	0.00363	0.0106	0.353
rs186132169	NGEF	NGEF_3_gene	EFHD1	-0.754	0.0035	0.0117	0.353
rs10933	PBRM1	PBRM1_2_gene	TNNC1	0.592	0.00495	0.0132	0.353
rs10933	PBRM1	PBRM1_3_gene	TNNC1	-0.753	0.00644	0.0137	0.353
rs4151680	PCDHA123	PCDHA123_1_gene	CYSTM1	0.22	0.00554	0.0122	0.353
rs4151680	PCDHA123	PCDHA123_1_gene	RELL2	0.289	0.00456	0.0108	0.353
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB9	0.246	0.00512	0.0144	0.353
rs4151680	PCDHA123	PCDHA123_3_gene	WDR55	0.216	0.0024	0.00938	0.353
rs301791	RERE	RERE_1_gene	PARK7	0.0863	0.00282	0.0105	0.353
rs324015	STAT6	STAT6_2_gene	ESYT1	0.269	0.00515	0.0135	0.353
rs324015	STAT6	STAT6_2_gene	RBMS2	0.274	0.0043	0.012	0.353
rs324015	STAT6	STAT6_2_gene	RPL41	0.166	0.00273	0.00941	0.353
rs324015	STAT6	STAT6_3_gene	ZC3H10	-0.342	0.00654	0.0144	0.353
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	SEC11A	0.235	0.00393	0.0127	0.353
rs2027349	VPS45	VPS45_2_gene	APH1A	0.16	0.00322	0.0106	0.353
rs2027349	VPS45	VPS45_3_gene	ANP32E	0.433	0.00676	0.0139	0.353
rs2027349	VPS45	VPS45_2_gene	C1orf54	0.24	0.00622	0.0154	0.368
rs12716973	KCTD13	KCTD13_2_gene	TMEM219	-0.253	0.00658	0.0163	0.377
rs12716973	KCTD13	KCTD13_3_gene	CCDC189	-0.496	0.00859	0.0168	0.377
rs10933	PBRM1	PBRM1_2_gene	PBRM1	-0.283	0.00858	0.0185	0.377
rs4151680	PCDHA123	PCDHA123_1_gene	NDUFA2	0.114	0.00946	0.0173	0.377
rs4151680	PCDHA123	PCDHA123_3_gene	APBB3	0.19	0.00772	0.0181	0.377
rs4151680	PCDHA123	PCDHA123_3_gene	HBEGF	0.243	0.0067	0.0166	0.377
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA4	-0.26	0.00778	0.0182	0.377
rs9882911	TRANK1	TRANK1_3_gene	GOLGA4	0.128	0.00802	0.0181	0.377
rs324017	NAB2	NAB2_2_gene	MYL6	-0.206	0.00882	0.019	0.381
rs6071578	PPP1R16B	PPP1R16B_1_gene	SLC32A1	-0.343	0.0105	0.0205	0.401
rs324015	STAT6	STAT6_1_gene	DCTN2	0.119	0.0108	0.0208	0.401
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	NMB	0.376	0.0093	0.0213	0.405
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA6	0.203	0.0108	0.0223	0.405
rs301791	RERE	RERE_3_gene	PER3	-0.376	0.0142	0.0228	0.405
rs324015	STAT6	STAT6_1_gene	NACA	0.102	0.0117	0.0218	0.405
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	GOLGA6L4	-0.507	0.0101	0.0225	0.405
rs12716973	KCTD13	KCTD13_2_gene	KCTD13	0.379	0.0135	0.0259	0.431
rs7936858	LOC100507431	LOC100507431_2_gene	NTM	-0.373	0.0154	0.0274	0.431
rs324017	NAB2	NAB2_1_gene	NABP2	-0.158	0.0171	0.0282	0.431
rs324017	NAB2	NAB2_2_gene	ATP23	-0.335	0.0154	0.028	0.431
rs324017	NAB2	NAB2_2_gene	PA2G4	-0.164	0.014	0.0264	0.431
rs10933	PBRM1	PBRM1_1_gene	NT5DC2	0.294	0.0149	0.0256	0.431
rs10933	PBRM1	PBRM1_2_gene	TKT	0.21	0.0146	0.0267	0.431
rs4151680	PCDHA123	PCDHA123_1_gene	HARS	0.133	0.0169	0.0268	0.431
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHGC3	0.216	0.0149	0.0277	0.431
rs324015	STAT6	STAT6_2_gene	METTL1	0.237	0.016	0.0277	0.431
rs2027349	VPS45	VPS45_2_gene	MRPS21	0.0822	0.0164	0.0286	0.432
rs4151680	PCDHA123	PCDHA123_1_gene	APBB3	0.217	0.0188	0.029	0.432
rs7170068	CHRNA3	CHRNA3_2_gene	CHRNA3	0.516	0.0161	0.0296	0.434
rs12716973	KCTD13	KCTD13_2_gene	ZNF768	-0.315	0.017	0.0305	0.442
rs7170068	CHRNA3	CHRNA3_2_gene	DNAJA4	0.374	0.0189	0.0331	0.458
rs7170068	CHRNA3	CHRNA3_2_gene	PSMA4	-0.167	0.0188	0.0329	0.458
rs12716973	KCTD13	KCTD13_2_gene	SEZ6L2	-0.288	0.0201	0.0342	0.458
rs324017	NAB2	NAB2_1_gene	NXPH4	-0.315	0.023	0.0351	0.458
rs324017	NAB2	NAB2_1_gene	OS9	-0.12	0.0211	0.0329	0.458
rs324017	NAB2	NAB2_2_gene	PAN2	-0.306	0.0209	0.0346	0.458
rs9882911	TRANK1	TRANK1_3_gene	LRRFIP2	0.124	0.0214	0.0354	0.458
rs2027349	VPS45	VPS45_3_gene	CIART	0.439	0.0246	0.0345	0.458
rs2027349	VPS45	VPS45_3_gene	MLLT11	-0.312	0.0247	0.0347	0.458
rs324017	NAB2	NAB2_2_gene	NDUFA4L2	-0.333	0.022	0.036	0.461
rs12716973	KCTD13	KCTD13_3_gene	ALDOA	-0.385	0.0254	0.0373	0.472
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB10	0.231	0.0273	0.0386	0.483
rs7148456	BAG5	BAG5_2_gene	XRCC3	-0.215	0.0245	0.0411	0.493
rs12716973	KCTD13	KCTD13_1_gene	ZNF48	-0.215	0.0237	0.0411	0.493
rs12716973	KCTD13	KCTD13_3_gene	HIRIP3	-0.392	0.029	0.0412	0.493
rs2027349	VPS45	VPS45_2_gene	ANP32E	0.167	0.0274	0.0412	0.493
rs2027349	VPS45	VPS45_3_gene	CA14	0.442	0.0315	0.0419	0.496
rs12716973	KCTD13	KCTD13_1_gene	ALDOA	-0.228	0.0261	0.044	0.5
rs3861678	LINC00637	LINC00637_2_gene	PPP1R13B	-0.233	0.028	0.0434	0.5
rs324017	NAB2	NAB2_1_gene	DCTN2	-0.0955	0.0308	0.044	0.5
rs324017	NAB2	NAB2_2_gene	PTGES3	-0.124	0.0276	0.0428	0.5
rs17200916	LOC105376975	LOC105376975_3_gene	SATB1	-0.308	0.0317	0.0446	0.502
rs4151680	PCDHA123	PCDHA123_1_gene	PURA	0.161	0.0338	0.0456	0.502
rs324015	STAT6	STAT6_1_gene	PAN2	0.245	0.0329	0.0456	0.502
rs2027349	VPS45	VPS45_1_gene	VPS45	-0.302	0.0304	0.0462	0.504
rs7148456	BAG5	BAG5_1_gene	XRCC3	-0.293	0.0296	0.048	0.507
rs12895055	BCL11B	BCL11B_3_gene	SETD3	-0.246	0.0335	0.0488	0.507
rs4151680	PCDHA123	PCDHA123_2_gene	HARS2	-0.194	0.0302	0.0475	0.507
rs324015	STAT6	STAT6_3_gene	STAT6	0.24	0.0358	0.047	0.507
rs2027349	VPS45	VPS45_2_gene	MCL1	0.115	0.0341	0.0486	0.507
rs10933	PBRM1	PBRM1_2_gene	SFMBT1	-0.402	0.0341	0.0505	0.519
rs2027349	VPS45	VPS45_3_gene	SV2A	-0.361	0.04	0.0509	0.519
rs3861678	LINC00637	LINC00637_1_gene	TRAF3	-0.179	0.0352	0.0531	0.537
rs12895055	BCL11B	BCL11B_1_gene	SETD3	-0.253	0.0368	0.0558	0.558
rs324017	NAB2	NAB2_3_gene	MBD6	-0.262	0.041	0.059	0.567
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA6	0.19	0.0469	0.0595	0.567
rs301791	RERE	RERE_1_gene	ENO1	0.0953	0.0399	0.0586	0.567
rs324015	STAT6	STAT6_1_gene	PTGES3	0.1	0.0458	0.0595	0.567
rs324015	STAT6	STAT6_3_gene	ESYT1	0.204	0.0462	0.0577	0.567
rs324015	STAT6	STAT6_3_gene	MYL6B	0.0956	0.0483	0.0597	0.567
rs186132169	NGEF	NGEF_3_gene	EIF4E2	0.296	0.0411	0.0611	0.575
rs7148456	BAG5	BAG5_2_gene	APOPT1	-0.108	0.0531	0.0731	0.577
rs7148456	BAG5	BAG5_3_gene	TRMT61A	0.302	0.052	0.0671	0.577
rs7170068	CHRNA3	CHRNA3_1_gene	CRABP1	0.693	0.062	0.08	0.577
rs9661794	DPYD	DPYD_1_gene	MIR137HG	-0.211	0.0488	0.0679	0.577
rs520843	GALNT10	GALNT10_1_gene	FAM114A2	-0.164	0.0532	0.065	0.577
rs520843	GALNT10	GALNT10_3_gene	MFAP3	-0.198	0.0476	0.0697	0.577
rs12716973	KCTD13	KCTD13_1_gene	BCL7C	-0.158	0.0511	0.0737	0.577
rs12716973	KCTD13	KCTD13_2_gene	ALDOA	-0.256	0.0489	0.0667	0.577
rs12716973	KCTD13	KCTD13_3_gene	FBRS	0.38	0.0524	0.0667	0.577
rs3861678	LINC00637	LINC00637_2_gene	ADSSL1	-0.202	0.0559	0.0737	0.577
rs3861678	LINC00637	LINC00637_2_gene	CDC42BPB	-0.148	0.0487	0.0662	0.577
rs3861678	LINC00637	LINC00637_3_gene	ZFYVE21	-0.142	0.0524	0.07	0.577
rs324017	NAB2	NAB2_1_gene	NDUFA4L2	-0.223	0.0629	0.0779	0.577
rs324017	NAB2	NAB2_2_gene	CDK4	-0.206	0.0564	0.0744	0.577
rs324017	NAB2	NAB2_2_gene	MBD6	0.27	0.0621	0.0808	0.577
rs324017	NAB2	NAB2_2_gene	METTL1	-0.24	0.057	0.0752	0.577
rs324017	NAB2	NAB2_3_gene	PAN2	-0.333	0.0628	0.0821	0.577
rs186132169	NGEF	NGEF_1_gene	HJURP	-0.483	0.0623	0.0764	0.577
rs186132169	NGEF	NGEF_2_gene	ECEL1	0.728	0.043	0.0645	0.577
rs186132169	NGEF	NGEF_2_gene	USP40	-0.643	0.0539	0.0768	0.577
rs10933	PBRM1	PBRM1_1_gene	GLT8D1	0.253	0.0657	0.08	0.577
rs10933	PBRM1	PBRM1_1_gene	GNL3	0.246	0.0589	0.0732	0.577
rs10933	PBRM1	PBRM1_2_gene	DUSP7	-0.406	0.0547	0.0733	0.577
rs10933	PBRM1	PBRM1_2_gene	TWF2	0.269	0.0468	0.0649	0.577
rs4151680	PCDHA123	PCDHA123_1_gene	HBEGF	0.229	0.0498	0.0627	0.577
rs4151680	PCDHA123	PCDHA123_2_gene	PFDN1	0.0769	0.0617	0.0824	0.577
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA10	-0.145	0.066	0.0838	0.577
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB10	0.145	0.067	0.0847	0.577
rs324015	STAT6	STAT6_1_gene	ANKRD52	0.216	0.05	0.0638	0.577
rs324015	STAT6	STAT6_1_gene	MARS	0.162	0.049	0.0628	0.577
rs324015	STAT6	STAT6_1_gene	METTL1	0.201	0.0709	0.0854	0.577
rs324015	STAT6	STAT6_1_gene	PA2G4	0.108	0.0702	0.0847	0.577
rs324015	STAT6	STAT6_1_gene	PRIM1	-0.23	0.0709	0.0854	0.577
rs324015	STAT6	STAT6_1_gene	RPL41	0.117	0.0696	0.084	0.577
rs324015	STAT6	STAT6_2_gene	DDIT3	0.192	0.05	0.0657	0.577
rs324015	STAT6	STAT6_2_gene	NAB2	0.181	0.0689	0.0848	0.577
rs324015	STAT6	STAT6_2_gene	RNF41	0.147	0.0662	0.0822	0.577
rs324015	STAT6	STAT6_3_gene	MARS	0.142	0.0677	0.0787	0.577
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ZNF592	0.355	0.0686	0.08	0.577
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	PDE8A	0.376	0.0525	0.0786	0.577
rs2027349	VPS45	VPS45_1_gene	CA14	0.381	0.0626	0.081	0.577
rs2027349	VPS45	VPS45_1_gene	PLEKHO1	0.195	0.055	0.073	0.577
rs2027349	VPS45	VPS45_2_gene	CERS2	0.133	0.065	0.0806	0.577
rs2027349	VPS45	VPS45_2_gene	PLEKHO1	0.0882	0.0618	0.0776	0.577
rs2027349	VPS45	VPS45_3_gene	C1orf54	0.337	0.0753	0.0859	0.577
rs2027349	VPS45	VPS45_3_gene	RPRD2	0.262	0.0717	0.0824	0.577
rs2027349	VPS45	VPS45_3_gene	SF3B4	0.193	0.0683	0.079	0.577
rs7170068	CHRNA3	CHRNA3_1_gene	CHRNA3	0.51	0.07	0.0883	0.58
rs7170068	CHRNA3	CHRNA3_3_gene	DNAJA4	0.362	0.0677	0.0911	0.58
rs12716973	KCTD13	KCTD13_2_gene	MVP	-0.28	0.0709	0.09	0.58
rs12716973	KCTD13	KCTD13_3_gene	ZNF768	-0.315	0.0747	0.0902	0.58
rs324017	NAB2	NAB2_1_gene	ANKRD52	-0.184	0.0765	0.0915	0.58
rs324017	NAB2	NAB2_1_gene	SHMT2	-0.18	0.0751	0.0901	0.58
rs10933	PBRM1	PBRM1_3_gene	GLYCTK	-0.4	0.0747	0.0888	0.58
rs324015	STAT6	STAT6_1_gene	ARHGEF25	0.214	0.0744	0.0889	0.58
rs324015	STAT6	STAT6_2_gene	R3HDM2	-0.143	0.0754	0.0916	0.58
rs2027349	VPS45	VPS45_1_gene	ANP32E	0.291	0.0716	0.0903	0.58
rs9882911	TRANK1	TRANK1_1_gene	MLH1	-1.06	0.0668	0.0948	0.596
rs324017	NAB2	NAB2_3_gene	ZC3H10	-0.215	0.078	0.0976	0.607
rs6071578	PPP1R16B	PPP1R16B_1_gene	FAM83D	0.197	0.0843	0.0976	0.607
rs6071578	PPP1R16B	PPP1R16B_3_gene	SLC32A1	-0.263	0.0767	0.0982	0.608
rs7170068	CHRNA3	CHRNA3_2_gene	CTSH	-0.263	0.0778	0.0988	0.608
rs7148456	BAG5	BAG5_1_gene	TRMT61A	-0.19	0.0797	0.104	0.609
rs520843	GALNT10	GALNT10_3_gene	LARP1	-0.0982	0.0753	0.1	0.609
rs12716973	KCTD13	KCTD13_1_gene	PRR14	-0.178	0.0797	0.106	0.609
rs12716973	KCTD13	KCTD13_2_gene	ZNF785	-0.257	0.0834	0.103	0.609
rs3861678	LINC00637	LINC00637_2_gene	ZFYVE21	-0.151	0.0838	0.103	0.609
rs324017	NAB2	NAB2_2_gene	RPL41	-0.126	0.0816	0.101	0.609
rs4151680	PCDHA123	PCDHA123_2_gene	WDR55	-0.153	0.0831	0.105	0.609
rs4151680	PCDHA123	PCDHA123_3_gene	CYSTM1	0.105	0.0862	0.105	0.609
rs301791	RERE	RERE_1_gene	H6PD	0.158	0.0794	0.102	0.609
rs301791	RERE	RERE_2_gene	PARK7	0.0705	0.0754	0.103	0.609
rs9882911	TRANK1	TRANK1_2_gene	MLH1	0.199	0.0978	0.101	0.609
rs2027349	VPS45	VPS45_1_gene	RPRD2	0.244	0.085	0.104	0.609
rs2027349	VPS45	VPS45_2_gene	CIART	0.141	0.0909	0.107	0.614
rs9661794	DPYD	DPYD_2_gene	MIR137HG	-0.137	0.0948	0.108	0.616
rs7170068	CHRNA3	CHRNA3_2_gene	CRABP1	-0.4	0.103	0.124	0.617
rs520843	GALNT10	GALNT10_2_gene	FAM114A2	-0.165	0.0847	0.122	0.617
rs12716973	KCTD13	KCTD13_1_gene	PPP4C	-0.106	0.0948	0.123	0.617
rs12716973	KCTD13	KCTD13_2_gene	MAPK3	0.194	0.0898	0.11	0.617
rs12716973	KCTD13	KCTD13_2_gene	PRRT2	0.278	0.0987	0.119	0.617
rs12716973	KCTD13	KCTD13_3_gene	ZNF689	0.343	0.0966	0.112	0.617
rs2192932	KMT2E	KMT2E_2_gene	ATXN7L1	-0.204	0.0981	0.117	0.617
rs3861678	LINC00637	LINC00637_1_gene	PPP1R13B	0.18	0.0912	0.113	0.617
rs3861678	LINC00637	LINC00637_1_gene	SIVA1	-0.124	0.0967	0.119	0.617
rs3861678	LINC00637	LINC00637_2_gene	APOPT1	-0.104	0.0945	0.114	0.617
rs7936858	LOC100507431	LOC100507431_1_gene	APLP2	-0.162	0.0943	0.112	0.617
rs324017	NAB2	NAB2_1_gene	MARCH9	-0.146	0.11	0.125	0.617
rs324017	NAB2	NAB2_2_gene	TIMELESS	-0.231	0.0955	0.116	0.617
rs324017	NAB2	NAB2_3_gene	R3HDM2	-0.165	0.0985	0.119	0.617
rs186132169	NGEF	NGEF_1_gene	EIF4E2	0.198	0.109	0.124	0.617
rs186132169	NGEF	NGEF_3_gene	HJURP	0.456	0.085	0.109	0.617
rs10933	PBRM1	PBRM1_2_gene	SPCS1	0.129	0.0979	0.119	0.617
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA10	0.136	0.1	0.123	0.617
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHGB6	0.14	0.0985	0.121	0.617
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHGB7	-0.16	0.1	0.123	0.617
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB14	0.144	0.0948	0.114	0.617
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHGB7	-0.167	0.0947	0.114	0.617
rs324015	STAT6	STAT6_1_gene	CTDSP2	0.178	0.0984	0.113	0.617
rs324015	STAT6	STAT6_2_gene	OS9	0.0772	0.105	0.121	0.617
rs324015	STAT6	STAT6_3_gene	DTX3	-0.157	0.108	0.117	0.617
rs324015	STAT6	STAT6_3_gene	MYL6	0.105	0.107	0.116	0.617
rs324015	STAT6	STAT6_3_gene	NXPH4	0.212	0.114	0.123	0.617
rs2027349	VPS45	VPS45_2_gene	ENSA	0.0695	0.0989	0.115	0.617
rs2027349	VPS45	VPS45_3_gene	APH1A	0.189	0.107	0.116	0.617
rs324017	NAB2	NAB2_2_gene	OS9	0.103	0.106	0.127	0.622
rs2027349	VPS45	VPS45_1_gene	MRPS21	0.12	0.107	0.126	0.622
rs324015	STAT6	STAT6_3_gene	CNPY2	0.1	0.118	0.127	0.623
rs7170068	CHRNA3	CHRNA3_2_gene	IREB2	-0.174	0.107	0.128	0.625
rs12716973	KCTD13	KCTD13_1_gene	ZNF771	-0.163	0.102	0.13	0.627
rs324015	STAT6	STAT6_1_gene	BAZ2A	0.142	0.116	0.13	0.627
rs4151680	PCDHA123	PCDHA123_3_gene	PFDN1	0.0601	0.112	0.131	0.629
rs6071578	PPP1R16B	PPP1R16B_2_gene	RALGAPB	0.147	0.122	0.131	0.629
rs9882911	TRANK1	TRANK1_2_gene	EPM2AIP1	0.147	0.13	0.132	0.63
rs324017	NAB2	NAB2_3_gene	DDIT3	-0.203	0.112	0.133	0.631
rs324015	STAT6	STAT6_3_gene	AGAP2	0.187	0.126	0.134	0.635
rs7148456	BAG5	BAG5_2_gene	CKB	-0.0973	0.144	0.167	0.638
rs7148456	BAG5	BAG5_2_gene	ZFYVE21	-0.123	0.113	0.136	0.638
rs7148456	BAG5	BAG5_3_gene	BAG5	0.173	0.142	0.158	0.638
rs7148456	BAG5	BAG5_3_gene	CKB	0.166	0.127	0.143	0.638
rs7148456	BAG5	BAG5_3_gene	RCOR1	-0.219	0.12	0.137	0.638
rs12895055	BCL11B	BCL11B_2_gene	SETD3	-0.112	0.137	0.169	0.638
rs7170068	CHRNA3	CHRNA3_1_gene	DNAJA4	0.274	0.153	0.171	0.638
rs520843	GALNT10	GALNT10_3_gene	MRPL22	-0.081	0.137	0.165	0.638
rs12716973	KCTD13	KCTD13_1_gene	PHKG2	0.167	0.117	0.146	0.638
rs12716973	KCTD13	KCTD13_1_gene	ZNF747	0.217	0.132	0.162	0.638
rs12716973	KCTD13	KCTD13_2_gene	SEPHS2	-0.157	0.149	0.17	0.638
rs12716973	KCTD13	KCTD13_2_gene	TAOK2	-0.234	0.142	0.163	0.638
rs12716973	KCTD13	KCTD13_3_gene	MVP	0.34	0.135	0.151	0.638
rs12716973	KCTD13	KCTD13_3_gene	ZNF629	0.301	0.141	0.156	0.638
rs2192932	KMT2E	KMT2E_2_gene	SRPK2	-0.0978	0.141	0.16	0.638
rs2192932	KMT2E	KMT2E_3_gene	CDHR3	0.213	0.158	0.172	0.638
rs3861678	LINC00637	LINC00637_1_gene	KLC1	-0.0986	0.141	0.163	0.638
rs3861678	LINC00637	LINC00637_2_gene	INF2	-0.179	0.128	0.148	0.638
rs3861678	LINC00637	LINC00637_2_gene	KLC1	-0.103	0.152	0.171	0.638
rs3861678	LINC00637	LINC00637_2_gene	TRAF3	0.14	0.14	0.159	0.638
rs3861678	LINC00637	LINC00637_3_gene	CKB	-0.0976	0.124	0.143	0.638
rs3861678	LINC00637	LINC00637_3_gene	KLC1	-0.0873	0.151	0.169	0.638
rs7936858	LOC100507431	LOC100507431_3_gene	APLP2	-0.0838	0.131	0.15	0.638
rs324017	NAB2	NAB2_1_gene	BAZ2A	-0.125	0.152	0.167	0.638
rs324017	NAB2	NAB2_1_gene	MYL6	-0.1	0.134	0.149	0.638
rs324017	NAB2	NAB2_1_gene	RNF41	-0.135	0.128	0.143	0.638
rs324017	NAB2	NAB2_1_gene	SMARCC2	-0.113	0.138	0.153	0.638
rs324017	NAB2	NAB2_1_gene	ZBTB39	-0.199	0.137	0.152	0.638
rs324017	NAB2	NAB2_2_gene	ESYT1	-0.197	0.129	0.15	0.638
rs324017	NAB2	NAB2_2_gene	MARCH9	-0.169	0.12	0.141	0.638
rs324017	NAB2	NAB2_2_gene	ZC3H10	-0.194	0.13	0.151	0.638
rs186132169	NGEF	NGEF_2_gene	EFHD1	0.448	0.141	0.166	0.638
rs186132169	NGEF	NGEF_2_gene	GIGYF2	-0.331	0.122	0.147	0.638
rs10933	PBRM1	PBRM1_1_gene	SPCS1	0.123	0.133	0.145	0.638
rs10933	PBRM1	PBRM1_1_gene	WDR82	0.172	0.128	0.14	0.638
rs10933	PBRM1	PBRM1_2_gene	RPL29	0.142	0.119	0.14	0.638
rs10933	PBRM1	PBRM1_3_gene	ABHD14A	0.209	0.155	0.168	0.638
rs10933	PBRM1	PBRM1_3_gene	RRP9	0.229	0.15	0.164	0.638
rs10933	PBRM1	PBRM1_3_gene	SFMBT1	-0.296	0.149	0.162	0.638
rs10933	PBRM1	PBRM1_3_gene	WDR82	0.165	0.157	0.171	0.638
rs4151680	PCDHA123	PCDHA123_1_gene	IK	0.0654	0.153	0.166	0.638
rs4151680	PCDHA123	PCDHA123_1_gene	SRA1	0.0963	0.138	0.152	0.638
rs4151680	PCDHA123	PCDHA123_2_gene	APBB3	0.117	0.135	0.158	0.638
rs4151680	PCDHA123	PCDHA123_3_gene	HARS	0.064	0.134	0.153	0.638
rs4151680	PCDHA123	PCDHA123_3_gene	ZMAT2	0.0671	0.121	0.14	0.638
rs301791	RERE	RERE_2_gene	PER3	0.199	0.11	0.14	0.638
rs301791	RERE	RERE_3_gene	H6PD	0.182	0.14	0.149	0.638
rs324015	STAT6	STAT6_1_gene	COQ10A	-0.171	0.146	0.159	0.638
rs324015	STAT6	STAT6_1_gene	CS	0.137	0.127	0.14	0.638
rs324015	STAT6	STAT6_1_gene	OS9	0.0786	0.156	0.169	0.638
rs324015	STAT6	STAT6_2_gene	LRP1	0.135	0.138	0.153	0.638
rs324015	STAT6	STAT6_2_gene	PA2G4	0.0738	0.154	0.169	0.638
rs324015	STAT6	STAT6_3_gene	ATP23	0.169	0.158	0.166	0.638
rs324015	STAT6	STAT6_3_gene	B4GALNT1	0.152	0.164	0.172	0.638
rs324015	STAT6	STAT6_3_gene	MARCH9	0.131	0.136	0.145	0.638
rs324015	STAT6	STAT6_3_gene	NABP2	0.091	0.163	0.171	0.638
rs324015	STAT6	STAT6_3_gene	PTGES3	0.0656	0.156	0.164	0.638
rs9882911	TRANK1	TRANK1_1_gene	EPM2AIP1	0.568	0.108	0.144	0.638
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	WDR73	0.215	0.159	0.168	0.638
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ZSCAN2	-0.324	0.11	0.142	0.638
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ALPK3	0.252	0.133	0.157	0.638
rs2027349	VPS45	VPS45_1_gene	TARS2	0.219	0.139	0.158	0.638
rs2027349	VPS45	VPS45_3_gene	CERS2	0.221	0.159	0.167	0.638
rs2027349	VPS45	VPS45_3_gene	ECM1	-0.341	0.135	0.144	0.638
rs324017	NAB2	NAB2_2_gene	AGAP2	-0.185	0.152	0.173	0.639
rs520843	GALNT10	GALNT10_3_gene	GALNT10	-0.137	0.148	0.176	0.645
rs2192932	KMT2E	KMT2E_1_gene	ORC5	0.356	0.148	0.176	0.645
rs7170068	CHRNA3	CHRNA3_1_gene	TBC1D2B	-0.253	0.162	0.179	0.653
rs186132169	NGEF	NGEF_3_gene	ECEL1	0.413	0.153	0.18	0.653
rs324015	STAT6	STAT6_1_gene	STAT2	0.175	0.168	0.18	0.653
rs9882911	TRANK1	TRANK1_3_gene	ITGA9	-0.125	0.161	0.18	0.653
rs12895055	BCL11B	BCL11B_2_gene	YY1	-0.0689	0.151	0.183	0.657
rs12716973	KCTD13	KCTD13_1_gene	ASPHD1	0.18	0.153	0.184	0.657
rs12716973	KCTD13	KCTD13_1_gene	QPRT	-0.142	0.155	0.185	0.657
rs324017	NAB2	NAB2_1_gene	B4GALNT1	-0.155	0.171	0.186	0.657
rs10933	PBRM1	PBRM1_2_gene	PCBP4	-0.197	0.164	0.185	0.657
rs10933	PBRM1	PBRM1_2_gene	SMIM4	0.207	0.163	0.184	0.657
rs324015	STAT6	STAT6_3_gene	NAB2	0.145	0.177	0.184	0.657
rs2027349	VPS45	VPS45_1_gene	APH1A	0.162	0.168	0.186	0.658
rs7170068	CHRNA3	CHRNA3_2_gene	WDR61	-0.124	0.168	0.19	0.662
rs12716973	KCTD13	KCTD13_3_gene	PPP4C	-0.147	0.175	0.191	0.662
rs1198588	miR137	miR137_3_gene	PLPPR5	0.116	0.17	0.191	0.662
rs186132169	NGEF	NGEF_1_gene	ATG16L1	0.242	0.175	0.189	0.662
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA12	0.122	0.177	0.191	0.662
rs4151680	PCDHA123	PCDHA123_2_gene	SLC35A4	-0.0981	0.167	0.19	0.662
rs7148456	BAG5	BAG5_2_gene	TRAF3	-0.111	0.174	0.196	0.663
rs12895055	BCL11B	BCL11B_3_gene	CYP46A1	-0.205	0.176	0.197	0.663
rs12716973	KCTD13	KCTD13_2_gene	BCL7C	-0.142	0.175	0.195	0.663
rs12716973	KCTD13	KCTD13_3_gene	PRR14	-0.229	0.182	0.197	0.663
rs324017	NAB2	NAB2_1_gene	RPL41	-0.0819	0.181	0.194	0.663
rs324017	NAB2	NAB2_2_gene	MYL6B	0.0819	0.178	0.198	0.663
rs4151680	PCDHA123	PCDHA123_2_gene	DIAPH1	0.101	0.177	0.2	0.663
rs4151680	PCDHA123	PCDHA123_3_gene	TAF7	0.0495	0.174	0.193	0.663
rs324015	STAT6	STAT6_1_gene	AVIL	-0.193	0.188	0.2	0.663
rs324015	STAT6	STAT6_1_gene	PIP4K2C	0.148	0.187	0.199	0.663
rs324015	STAT6	STAT6_1_gene	R3HDM2	0.12	0.185	0.196	0.663
rs324015	STAT6	STAT6_1_gene	TIMELESS	0.161	0.186	0.198	0.663
rs324015	STAT6	STAT6_2_gene	CTDSP2	0.128	0.18	0.194	0.663
rs2027349	VPS45	VPS45_2_gene	SF3B4	0.0656	0.185	0.199	0.663
rs186132169	NGEF	NGEF_1_gene	USP40	-0.256	0.187	0.201	0.663
rs4151680	PCDHA123	PCDHA123_1_gene	ANKHD1	-0.125	0.189	0.202	0.666
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	NMB	0.235	0.195	0.203	0.668
rs7170068	CHRNA3	CHRNA3_2_gene	CHRNA5	-0.197	0.185	0.208	0.669
rs12716973	KCTD13	KCTD13_1_gene	TMEM219	-0.101	0.175	0.206	0.669
rs12716973	KCTD13	KCTD13_3_gene	DOC2A	-0.256	0.192	0.207	0.669
rs324017	NAB2	NAB2_1_gene	PTGES3	-0.0617	0.194	0.208	0.669
rs324017	NAB2	NAB2_3_gene	NAB2	0.18	0.186	0.206	0.669
rs324015	STAT6	STAT6_2_gene	SHMT2	0.12	0.191	0.205	0.669
rs324015	STAT6	STAT6_3_gene	KIF5A	0.138	0.199	0.205	0.669
rs7148456	BAG5	BAG5_3_gene	APOPT1	-0.114	0.195	0.209	0.67
rs7148456	BAG5	BAG5_3_gene	EIF5	-0.1	0.202	0.216	0.67
rs7170068	CHRNA3	CHRNA3_1_gene	MORF4L1	-0.0791	0.198	0.215	0.67
rs9661794	DPYD	DPYD_1_gene	SNX7	-0.136	0.195	0.216	0.67
rs12716973	KCTD13	KCTD13_2_gene	SPNS1	0.183	0.192	0.211	0.67
rs3861678	LINC00637	LINC00637_1_gene	MARK3	-0.0795	0.19	0.212	0.67
rs7936858	LOC100507431	LOC100507431_1_gene	ZBTB44	0.205	0.197	0.215	0.67
rs4151680	PCDHA123	PCDHA123_1_gene	ZMAT2	0.0731	0.198	0.211	0.67
rs6071578	PPP1R16B	PPP1R16B_1_gene	RALGAPB	0.114	0.199	0.21	0.67
rs324015	STAT6	STAT6_1_gene	MYL6B	-0.0688	0.202	0.213	0.67
rs324015	STAT6	STAT6_1_gene	ZC3H10	-0.142	0.205	0.216	0.67
rs324015	STAT6	STAT6_2_gene	AVIL	0.135	0.202	0.215	0.67
rs324015	STAT6	STAT6_2_gene	TSFM	0.0967	0.201	0.214	0.67
rs12716973	KCTD13	KCTD13_1_gene	SEPHS2	0.117	0.188	0.219	0.671
rs324015	STAT6	STAT6_1_gene	LRP1	0.132	0.207	0.218	0.671
rs324015	STAT6	STAT6_1_gene	TSPAN31	0.124	0.208	0.219	0.671
rs324015	STAT6	STAT6_2_gene	DCTN2	0.0513	0.205	0.218	0.671
rs324017	NAB2	NAB2_1_gene	PRIM1	0.149	0.208	0.221	0.676
rs7170068	CHRNA3	CHRNA3_3_gene	PSMA4	-0.107	0.196	0.224	0.679
rs520843	GALNT10	GALNT10_2_gene	GEMIN5	-0.141	0.179	0.223	0.679
rs10933	PBRM1	PBRM1_2_gene	ABHD14B	0.224	0.203	0.224	0.679
rs1198588	miR137	miR137_2_gene	PLPPR5	-0.197	0.209	0.227	0.685
rs324017	NAB2	NAB2_1_gene	CS	-0.107	0.214	0.227	0.685
rs10933	PBRM1	PBRM1_3_gene	ALAS1	-0.199	0.217	0.228	0.686
rs324015	STAT6	STAT6_2_gene	DTX3	-0.111	0.216	0.229	0.688
rs520843	GALNT10	GALNT10_3_gene	FAM114A2	-0.0989	0.202	0.23	0.688
rs324015	STAT6	STAT6_2_gene	TSPAN31	0.106	0.217	0.23	0.688
rs3861678	LINC00637	LINC00637_1_gene	INF2	-0.124	0.215	0.237	0.7
rs324017	NAB2	NAB2_3_gene	PTGES3	-0.0701	0.216	0.236	0.7
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHGB6	-0.098	0.219	0.236	0.7
rs6071578	PPP1R16B	PPP1R16B_1_gene	SNHG11	0.104	0.226	0.237	0.7
rs7170068	CHRNA3	CHRNA3_2_gene	MORF4L1	-0.0574	0.221	0.242	0.71
rs301791	RERE	RERE_1_gene	VAMP3	0.0992	0.218	0.241	0.71
rs7148456	BAG5	BAG5_1_gene	EIF5	-0.0732	0.216	0.243	0.712
rs10933	PBRM1	PBRM1_2_gene	DCP1A	0.159	0.225	0.245	0.712
rs10933	PBRM1	PBRM1_3_gene	NISCH	-0.195	0.234	0.245	0.712
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	AKAP13	0.17	0.223	0.244	0.712
rs3861678	LINC00637	LINC00637_1_gene	ADSSL1	-0.127	0.224	0.246	0.712
rs7148456	BAG5	BAG5_2_gene	RCOR1	0.112	0.23	0.25	0.714
rs7170068	CHRNA3	CHRNA3_1_gene	TMED3	-0.155	0.237	0.252	0.714
rs12716973	KCTD13	KCTD13_1_gene	SEPT1	0.142	0.224	0.255	0.714
rs12716973	KCTD13	KCTD13_2_gene	INO80E	-0.146	0.229	0.248	0.714
rs12716973	KCTD13	KCTD13_3_gene	SPNS1	-0.287	0.239	0.254	0.714
rs12716973	KCTD13	KCTD13_3_gene	YPEL3	-0.193	0.236	0.251	0.714
rs2192932	KMT2E	KMT2E_1_gene	CDHR3	-0.327	0.224	0.253	0.714
rs7936858	LOC100507431	LOC100507431_3_gene	NFRKB	0.111	0.233	0.25	0.714
rs186132169	NGEF	NGEF_1_gene	EFHD1	0.23	0.239	0.251	0.714
rs324015	STAT6	STAT6_1_gene	CDK4	0.113	0.245	0.254	0.714
rs324015	STAT6	STAT6_2_gene	CNPY2	0.0713	0.242	0.253	0.714
rs324015	STAT6	STAT6_2_gene	ZBTB39	0.125	0.242	0.253	0.714
rs2027349	VPS45	VPS45_1_gene	ECM1	0.243	0.238	0.255	0.714
rs2027349	VPS45	VPS45_2_gene	HIST2H2BE	0.103	0.236	0.248	0.714
rs7148456	BAG5	BAG5_2_gene	KLC1	0.0774	0.236	0.257	0.716
rs12716973	KCTD13	KCTD13_1_gene	RNF40	-0.109	0.227	0.258	0.717
rs7148456	BAG5	BAG5_3_gene	TRAF3	0.155	0.253	0.265	0.717
rs12895055	BCL11B	BCL11B_3_gene	CCNK	0.14	0.25	0.27	0.717
rs7170068	CHRNA3	CHRNA3_1_gene	IREB2	-0.165	0.25	0.265	0.717
rs520843	GALNT10	GALNT10_1_gene	MRPL22	-0.069	0.252	0.259	0.717
rs520843	GALNT10	GALNT10_2_gene	SAP30L	-0.128	0.226	0.271	0.717
rs12716973	KCTD13	KCTD13_1_gene	MAZ	-0.0617	0.232	0.263	0.717
rs12716973	KCTD13	KCTD13_1_gene	ZNF689	-0.139	0.233	0.264	0.717
rs12716973	KCTD13	KCTD13_2_gene	RNF40	-0.133	0.247	0.266	0.717
rs12716973	KCTD13	KCTD13_3_gene	MAPK3	-0.164	0.255	0.27	0.717
rs3861678	LINC00637	LINC00637_1_gene	CDC42BPB	-0.0819	0.249	0.27	0.717
rs3861678	LINC00637	LINC00637_3_gene	ADSSL1	-0.101	0.254	0.269	0.717
rs324017	NAB2	NAB2_2_gene	PRIM1	-0.162	0.239	0.26	0.717
rs10933	PBRM1	PBRM1_1_gene	PCBP4	-0.167	0.26	0.269	0.717
rs10933	PBRM1	PBRM1_1_gene	POC1A	0.23	0.258	0.267	0.717
rs10933	PBRM1	PBRM1_2_gene	PHF7	0.222	0.243	0.262	0.717
rs6071578	PPP1R16B	PPP1R16B_3_gene	VSTM2L	-0.161	0.241	0.264	0.717
rs324015	STAT6	STAT6_2_gene	SMARCC2	-0.0821	0.25	0.26	0.717
rs324015	STAT6	STAT6_3_gene	ARHGEF25	0.113	0.26	0.264	0.717
rs2027349	VPS45	VPS45_1_gene	HIST2H2AC	0.226	0.246	0.262	0.717
rs2027349	VPS45	VPS45_2_gene	CA14	0.112	0.256	0.268	0.717
rs12716973	KCTD13	KCTD13_3_gene	CD2BP2	-0.176	0.259	0.273	0.72
rs12895055	BCL11B	BCL11B_1_gene	YY1	-0.0876	0.252	0.277	0.725
rs324017	NAB2	NAB2_2_gene	KIF5A	0.158	0.256	0.276	0.725
rs324015	STAT6	STAT6_1_gene	RNF41	0.105	0.266	0.276	0.725
rs7148456	BAG5	BAG5_1_gene	TRAF3	-0.112	0.257	0.283	0.729
rs12895055	BCL11B	BCL11B_1_gene	CCNK	0.144	0.256	0.28	0.729
rs12716973	KCTD13	KCTD13_1_gene	FAM57B	0.138	0.257	0.287	0.729
rs12716973	KCTD13	KCTD13_3_gene	ZNF688	0.219	0.272	0.286	0.729
rs324017	NAB2	NAB2_1_gene	RBMS2	-0.138	0.277	0.288	0.729
rs324017	NAB2	NAB2_2_gene	NAB2	-0.145	0.269	0.289	0.729
rs186132169	NGEF	NGEF_2_gene	HJURP	0.396	0.267	0.29	0.729
rs10933	PBRM1	PBRM1_3_gene	TEX264	-0.173	0.278	0.287	0.729
rs6071578	PPP1R16B	PPP1R16B_2_gene	ACTR5	0.137	0.278	0.281	0.729
rs301791	RERE	RERE_2_gene	CAMTA1	0.0663	0.261	0.29	0.729
rs324015	STAT6	STAT6_1_gene	DDIT3	0.123	0.28	0.29	0.729
rs324015	STAT6	STAT6_1_gene	SHMT2	0.116	0.278	0.287	0.729
rs324015	STAT6	STAT6_2_gene	KIF5A	-0.115	0.278	0.288	0.729
rs324015	STAT6	STAT6_2_gene	NXPH4	-0.145	0.275	0.285	0.729
rs324015	STAT6	STAT6_3_gene	TAC3	0.178	0.28	0.283	0.729
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	WDR73	0.14	0.269	0.29	0.729
rs2027349	VPS45	VPS45_1_gene	CERS2	0.174	0.265	0.282	0.729
rs2027349	VPS45	VPS45_3_gene	TARS2	-0.175	0.278	0.282	0.729
rs12716973	KCTD13	KCTD13_2_gene	CORO1A	-0.156	0.281	0.299	0.732
rs2192932	KMT2E	KMT2E_1_gene	SRPK2	-0.137	0.267	0.294	0.732
rs324017	NAB2	NAB2_2_gene	MARS	-0.102	0.278	0.297	0.732
rs324017	NAB2	NAB2_2_gene	NACA	-0.0503	0.274	0.294	0.732
rs324017	NAB2	NAB2_2_gene	STAT6	0.166	0.28	0.3	0.732
rs324017	NAB2	NAB2_3_gene	B4GALNT1	0.155	0.274	0.294	0.732
rs186132169	NGEF	NGEF_1_gene	TIGD1	-0.205	0.288	0.299	0.732
rs10933	PBRM1	PBRM1_1_gene	NISCH	0.159	0.292	0.3	0.732
rs10933	PBRM1	PBRM1_2_gene	NT5DC2	0.13	0.274	0.292	0.732
rs10933	PBRM1	PBRM1_3_gene	NT5DC2	-0.139	0.289	0.298	0.732
rs6071578	PPP1R16B	PPP1R16B_3_gene	ACTR5	0.12	0.275	0.297	0.732
rs301791	RERE	RERE_2_gene	ENO1	0.0705	0.267	0.296	0.732
rs2027349	VPS45	VPS45_1_gene	CDC42SE1	0.147	0.283	0.299	0.732
rs7170068	CHRNA3	CHRNA3_3_gene	IDH3A	0.165	0.282	0.309	0.735
rs12716973	KCTD13	KCTD13_2_gene	CD2BP2	-0.126	0.287	0.304	0.735
rs12716973	KCTD13	KCTD13_3_gene	KIF22	0.219	0.295	0.308	0.735
rs3861678	LINC00637	LINC00637_2_gene	EIF5	-0.0601	0.287	0.302	0.735
rs7936858	LOC100507431	LOC100507431_2_gene	SNX19	-0.148	0.296	0.308	0.735
rs10933	PBRM1	PBRM1_1_gene	RPL29	0.0999	0.297	0.304	0.735
rs4151680	PCDHA123	PCDHA123_3_gene	HARS2	-0.0783	0.292	0.307	0.735
rs324015	STAT6	STAT6_1_gene	NABP2	0.0737	0.298	0.307	0.735
rs324015	STAT6	STAT6_3_gene	PRIM1	-0.116	0.306	0.308	0.735
rs9882911	TRANK1	TRANK1_3_gene	MLH1	0.0679	0.287	0.304	0.735
rs2027349	VPS45	VPS45_1_gene	GOLPH3L	0.165	0.29	0.305	0.735
rs3861678	LINC00637	LINC00637_2_gene	AKT1	-0.0711	0.295	0.31	0.737
rs324015	STAT6	STAT6_2_gene	CDK4	0.0876	0.301	0.31	0.737
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB14	-0.088	0.293	0.312	0.738
rs2027349	VPS45	VPS45_2_gene	RPRD2	-0.0706	0.308	0.318	0.749
rs2027349	VPS45	VPS45_3_gene	MCL1	0.119	0.315	0.317	0.749
rs12716973	KCTD13	KCTD13_2_gene	ZNF688	-0.152	0.304	0.321	0.75
rs2192932	KMT2E	KMT2E_3_gene	SRPK2	0.0687	0.313	0.322	0.75
rs186132169	NGEF	NGEF_3_gene	GIGYF2	0.154	0.297	0.322	0.75
rs10933	PBRM1	PBRM1_1_gene	DUSP7	-0.222	0.316	0.322	0.75
rs10933	PBRM1	PBRM1_1_gene	TKT	0.0917	0.315	0.321	0.75
rs324015	STAT6	STAT6_3_gene	RBMS2	0.102	0.32	0.321	0.75
rs17200916	LOC105376975	LOC105376975_2_gene	TBC1D5	-0.0775	0.296	0.323	0.751
rs10933	PBRM1	PBRM1_1_gene	GRM2	-0.206	0.318	0.324	0.751
rs10933	PBRM1	PBRM1_1_gene	TNNC1	-0.237	0.318	0.324	0.751
rs324017	NAB2	NAB2_2_gene	AVIL	-0.16	0.308	0.327	0.755
rs7148456	BAG5	BAG5_3_gene	XRCC3	0.173	0.322	0.332	0.756
rs324017	NAB2	NAB2_1_gene	ATP23	0.117	0.319	0.33	0.756
rs10933	PBRM1	PBRM1_1_gene	GLYCTK	0.175	0.326	0.331	0.756
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHGA7	0.112	0.32	0.33	0.756
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ZNF592	0.15	0.311	0.33	0.756
rs2027349	VPS45	VPS45_3_gene	SETDB1	-0.165	0.329	0.331	0.756
rs4151680	PCDHA123	PCDHA123_1_gene	SLC35A4	0.0812	0.325	0.335	0.762
rs324015	STAT6	STAT6_2_gene	ZC3H10	0.089	0.328	0.336	0.763
rs324015	STAT6	STAT6_3_gene	NACA	0.0359	0.339	0.339	0.769
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHGA10	0.0813	0.324	0.343	0.773
rs324015	STAT6	STAT6_3_gene	BAZ2A	0.0802	0.342	0.342	0.773
rs6071578	PPP1R16B	PPP1R16B_2_gene	DHX35	0.12	0.345	0.344	0.775
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB15	-0.0749	0.328	0.346	0.777
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB5	0.113	0.328	0.346	0.777
rs12895055	BCL11B	BCL11B_1_gene	EML1	-0.143	0.327	0.349	0.78
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB2	0.0712	0.33	0.349	0.78
rs3861678	LINC00637	LINC00637_2_gene	CKB	0.0725	0.348	0.36	0.785
rs7936858	LOC100507431	LOC100507431_3_gene	ZBTB44	-0.0814	0.34	0.353	0.785
rs324017	NAB2	NAB2_1_gene	MYL6B	-0.047	0.348	0.357	0.785
rs324017	NAB2	NAB2_3_gene	COQ10A	-0.122	0.341	0.358	0.785
rs10933	PBRM1	PBRM1_2_gene	BAP1	0.151	0.341	0.357	0.785
rs10933	PBRM1	PBRM1_2_gene	NEK4	0.159	0.342	0.358	0.785
rs10933	PBRM1	PBRM1_3_gene	PCBP4	0.134	0.352	0.358	0.785
rs4151680	PCDHA123	PCDHA123_1_gene	HARS2	0.0976	0.351	0.36	0.785
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHGB7	-0.0897	0.348	0.357	0.785
rs324015	STAT6	STAT6_1_gene	ESYT1	0.102	0.351	0.36	0.785
rs324015	STAT6	STAT6_1_gene	NXPH4	0.138	0.351	0.359	0.785
rs324015	STAT6	STAT6_3_gene	PIP4K2C	0.0974	0.359	0.359	0.785
rs520843	GALNT10	GALNT10_2_gene	GRIA1	-0.12	0.325	0.367	0.788
rs3861678	LINC00637	LINC00637_1_gene	TRMT61A	-0.0872	0.349	0.367	0.788
rs7936858	LOC100507431	LOC100507431_1_gene	NTM	-0.177	0.354	0.365	0.788
rs324017	NAB2	NAB2_1_gene	LRP1	-0.0931	0.357	0.365	0.788
rs186132169	NGEF	NGEF_1_gene	ECEL1	-0.246	0.358	0.366	0.788
rs4151680	PCDHA123	PCDHA123_1_gene	HDAC3	0.0621	0.355	0.364	0.788
rs324015	STAT6	STAT6_3_gene	OS9	0.046	0.367	0.367	0.788
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	PDE8A	0.172	0.348	0.366	0.788
rs324017	NAB2	NAB2_3_gene	SMARCC2	-0.0851	0.351	0.368	0.788
rs324017	NAB2	NAB2_1_gene	PAN2	0.116	0.361	0.369	0.789
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB5	-0.0976	0.361	0.37	0.79
rs520843	GALNT10	GALNT10_1_gene	GEMIN5	-0.0813	0.373	0.374	0.794
rs12716973	KCTD13	KCTD13_1_gene	CTF1	-0.11	0.345	0.374	0.794
rs324017	NAB2	NAB2_3_gene	ATP23	-0.129	0.356	0.373	0.794
rs10933	PBRM1	PBRM1_3_gene	GRM2	-0.209	0.372	0.377	0.798
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA12	0.0709	0.365	0.382	0.807
rs7148456	BAG5	BAG5_2_gene	EIF5	-0.0446	0.371	0.387	0.808
rs12895055	BCL11B	BCL11B_3_gene	EVL	-0.0726	0.371	0.387	0.808
rs7936858	LOC100507431	LOC100507431_2_gene	NFRKB	0.116	0.377	0.387	0.808
rs324017	NAB2	NAB2_3_gene	METTL1	-0.113	0.369	0.385	0.808
rs324017	NAB2	NAB2_3_gene	STAT6	-0.107	0.369	0.386	0.808
rs186132169	NGEF	NGEF_3_gene	DGKD	-0.198	0.362	0.384	0.808
rs10933	PBRM1	PBRM1_2_gene	WDR82	0.0969	0.374	0.388	0.808
rs324015	STAT6	STAT6_2_gene	STAT2	0.0963	0.381	0.388	0.808
rs324017	NAB2	NAB2_1_gene	COQ10A	0.097	0.383	0.39	0.809
rs324017	NAB2	NAB2_3_gene	CNPY2	-0.0706	0.375	0.39	0.809
rs9882911	TRANK1	TRANK1_1_gene	GOLGA4	0.314	0.364	0.391	0.809
rs3861678	LINC00637	LINC00637_3_gene	TRAF3	0.0699	0.383	0.394	0.811
rs301791	RERE	RERE_3_gene	SLC45A1	-0.113	0.395	0.394	0.811
rs2027349	VPS45	VPS45_1_gene	ARNT	-0.171	0.382	0.394	0.811
rs7170068	CHRNA3	CHRNA3_3_gene	CIB2	-0.106	0.374	0.398	0.817
rs7148456	BAG5	BAG5_1_gene	MARK3	-0.0606	0.38	0.402	0.819
rs7148456	BAG5	BAG5_3_gene	PPP1R13B	-0.132	0.395	0.402	0.819
rs324017	NAB2	NAB2_3_gene	SPRYD4	-0.107	0.386	0.402	0.819
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	SEC11A	0.0845	0.398	0.401	0.819
rs3861678	LINC00637	LINC00637_3_gene	AKT1	-0.0488	0.396	0.406	0.825
rs9882911	TRANK1	TRANK1_2_gene	ITGA9	0.184	0.415	0.406	0.825
rs12895055	BCL11B	BCL11B_2_gene	CCNK	0.0673	0.386	0.412	0.826
rs12895055	BCL11B	BCL11B_3_gene	CCDC85C	0.139	0.396	0.412	0.826
rs9661794	DPYD	DPYD_3_gene	MIR137HG	0.111	0.405	0.41	0.826
rs324017	NAB2	NAB2_1_gene	TIMELESS	-0.0974	0.402	0.408	0.826
rs324017	NAB2	NAB2_3_gene	LRP1	-0.1	0.393	0.409	0.826
rs324015	STAT6	STAT6_2_gene	MBD6	-0.103	0.405	0.411	0.826
rs324015	STAT6	STAT6_3_gene	RPL41	0.049	0.411	0.41	0.826
rs7170068	CHRNA3	CHRNA3_3_gene	IREB2	0.11	0.4	0.421	0.829
rs520843	GALNT10	GALNT10_1_gene	LARP1	-0.049	0.424	0.424	0.829
rs12716973	KCTD13	KCTD13_2_gene	CDIPT	-0.0928	0.408	0.419	0.829
rs12716973	KCTD13	KCTD13_2_gene	SEPT1	-0.115	0.414	0.425	0.829
rs12716973	KCTD13	KCTD13_3_gene	SEPT1	0.167	0.414	0.423	0.829
rs324017	NAB2	NAB2_1_gene	ARHGEF25	-0.118	0.412	0.417	0.829
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB2	0.0726	0.407	0.415	0.829
rs4151680	PCDHA123	PCDHA123_1_gene	WDR55	0.0778	0.416	0.424	0.829
rs4151680	PCDHA123	PCDHA123_2_gene	IK	0.0323	0.399	0.414	0.829
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA6	0.0666	0.409	0.423	0.829
rs6071578	PPP1R16B	PPP1R16B_1_gene	CTNNBL1	0.0575	0.413	0.417	0.829
rs324015	STAT6	STAT6_3_gene	AVIL	-0.1	0.419	0.418	0.829
rs2027349	VPS45	VPS45_2_gene	BOLA1	0.078	0.414	0.421	0.829
rs2027349	VPS45	VPS45_3_gene	ARNT	-0.135	0.426	0.425	0.829
rs2027349	VPS45	VPS45_3_gene	BOLA1	0.19	0.42	0.419	0.829
rs7148456	BAG5	BAG5_3_gene	MARK3	-0.0745	0.421	0.427	0.83
rs12716973	KCTD13	KCTD13_3_gene	ZNF771	-0.142	0.418	0.426	0.83
rs324015	STAT6	STAT6_1_gene	CNPY2	0.0561	0.422	0.427	0.83
rs10933	PBRM1	PBRM1_2_gene	POC1A	0.167	0.417	0.43	0.833
rs4151680	PCDHA123	PCDHA123_1_gene	DIAPH1	-0.0731	0.423	0.43	0.833
rs520843	GALNT10	GALNT10_1_gene	SAP30L	-0.0712	0.434	0.434	0.833
rs12716973	KCTD13	KCTD13_3_gene	CDIPT	-0.118	0.426	0.435	0.833
rs12716973	KCTD13	KCTD13_3_gene	FAM57B	0.167	0.425	0.433	0.833
rs324017	NAB2	NAB2_1_gene	STAT2	-0.0798	0.43	0.434	0.833
rs9882911	TRANK1	TRANK1_2_gene	GOLGA4	0.072	0.446	0.436	0.833
rs2027349	VPS45	VPS45_2_gene	CDC42SE1	0.0525	0.429	0.436	0.833
rs2027349	VPS45	VPS45_2_gene	PRPF3	0.0576	0.428	0.435	0.833
rs7170068	CHRNA3	CHRNA3_1_gene	CTSH	-0.151	0.431	0.44	0.834
rs12716973	KCTD13	KCTD13_2_gene	CCDC189	0.124	0.427	0.438	0.834
rs324017	NAB2	NAB2_1_gene	AGAP2	0.105	0.437	0.44	0.834
rs324017	NAB2	NAB2_2_gene	CTDSP2	-0.102	0.425	0.441	0.834
rs186132169	NGEF	NGEF_3_gene	ATG16L1	-0.181	0.42	0.44	0.834
rs324015	STAT6	STAT6_2_gene	ATP23	0.0702	0.437	0.441	0.834
rs324017	NAB2	NAB2_2_gene	ZBTB39	0.114	0.428	0.443	0.837
rs12716973	KCTD13	KCTD13_2_gene	ZNF764	0.145	0.435	0.446	0.84
rs6071578	PPP1R16B	PPP1R16B_1_gene	VSTM2L	-0.0863	0.448	0.449	0.845
rs3861678	LINC00637	LINC00637_1_gene	ZFYVE21	-0.0637	0.437	0.451	0.848
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB16	-0.0706	0.44	0.453	0.85
rs3861678	LINC00637	LINC00637_1_gene	EIF5	-0.0403	0.442	0.457	0.854
rs186132169	NGEF	NGEF_1_gene	DIS3L2	-0.151	0.452	0.457	0.854
rs10933	PBRM1	PBRM1_1_gene	ABHD14A	-0.112	0.457	0.457	0.854
rs324015	STAT6	STAT6_1_gene	RBMS2	0.101	0.454	0.458	0.854
rs3861678	LINC00637	LINC00637_3_gene	XRCC3	-0.0612	0.452	0.459	0.854
rs2027349	VPS45	VPS45_2_gene	MLLT11	0.0454	0.455	0.46	0.855
rs4151680	PCDHA123	PCDHA123_2_gene	CYSTM1	0.0511	0.451	0.463	0.858
rs324015	STAT6	STAT6_3_gene	ANKRD52	0.095	0.466	0.463	0.858
rs324017	NAB2	NAB2_1_gene	SPRYD4	-0.079	0.461	0.464	0.858
rs324017	NAB2	NAB2_3_gene	TIMELESS	0.109	0.453	0.466	0.859
rs2027349	VPS45	VPS45_3_gene	PRPF3	0.113	0.469	0.466	0.859
rs324017	NAB2	NAB2_3_gene	AVIL	0.109	0.455	0.468	0.86
rs12716973	KCTD13	KCTD13_3_gene	ZNF48	-0.123	0.462	0.469	0.86
rs7170068	CHRNA3	CHRNA3_1_gene	CHRNA5	-0.153	0.462	0.47	0.861
rs324015	STAT6	STAT6_2_gene	SPRYD4	-0.0732	0.468	0.471	0.861
rs324017	NAB2	NAB2_3_gene	MARCH9	-0.0823	0.461	0.474	0.866
rs7170068	CHRNA3	CHRNA3_3_gene	CRABP1	-0.217	0.457	0.476	0.868
rs12895055	BCL11B	BCL11B_3_gene	YY1	0.0534	0.47	0.482	0.872
rs7170068	CHRNA3	CHRNA3_3_gene	CHRNA5	-0.133	0.464	0.483	0.872
rs12716973	KCTD13	KCTD13_1_gene	DOC2A	0.0824	0.459	0.484	0.872
rs12716973	KCTD13	KCTD13_1_gene	ZNF688	0.11	0.457	0.481	0.872
rs324017	NAB2	NAB2_3_gene	NDUFA4L2	-0.16	0.47	0.482	0.872
rs10933	PBRM1	PBRM1_1_gene	RRP9	0.11	0.484	0.484	0.872
rs324015	STAT6	STAT6_1_gene	MARCH9	0.0694	0.477	0.48	0.872
rs12716973	KCTD13	KCTD13_2_gene	QPRT	-0.0921	0.476	0.485	0.872
rs324017	NAB2	NAB2_3_gene	RBMS2	-0.123	0.473	0.486	0.872
rs301791	RERE	RERE_2_gene	SLC45A1	-0.0858	0.468	0.488	0.875
rs7170068	CHRNA3	CHRNA3_3_gene	LINGO1	-0.125	0.475	0.493	0.881
rs12716973	KCTD13	KCTD13_2_gene	CTF1	-0.124	0.486	0.494	0.881
rs324017	NAB2	NAB2_2_gene	SHMT2	-0.0837	0.481	0.495	0.881
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHGC3	0.0887	0.487	0.493	0.881
rs301791	RERE	RERE_3_gene	RERE	-0.0493	0.502	0.496	0.881
rs9882911	TRANK1	TRANK1_2_gene	STAC	0.0859	0.507	0.494	0.881
rs7148456	BAG5	BAG5_3_gene	ZFYVE21	-0.083	0.494	0.497	0.881
rs324017	NAB2	NAB2_3_gene	TSPAN31	-0.0786	0.486	0.498	0.881
rs12716973	KCTD13	KCTD13_2_gene	PPP4C	0.0577	0.491	0.499	0.881
rs6071578	PPP1R16B	PPP1R16B_2_gene	CTNNBL1	-0.0525	0.506	0.5	0.881
rs2027349	VPS45	VPS45_2_gene	C1orf56	0.0522	0.497	0.5	0.882
rs7148456	BAG5	BAG5_1_gene	CDC42BPB	0.0569	0.489	0.505	0.883
rs12716973	KCTD13	KCTD13_2_gene	PHKG2	-0.0889	0.496	0.504	0.883
rs12716973	KCTD13	KCTD13_3_gene	BOLA2B	0.178	0.497	0.503	0.883
rs301791	RERE	RERE_3_gene	TNFRSF9	0.113	0.511	0.505	0.883
rs324015	STAT6	STAT6_3_gene	SMARCC2	-0.0502	0.51	0.505	0.883
rs12716973	KCTD13	KCTD13_1_gene	CD2BP2	-0.064	0.485	0.508	0.884
rs12716973	KCTD13	KCTD13_2_gene	BOLA2B	-0.0949	0.501	0.508	0.884
rs3861678	LINC00637	LINC00637_1_gene	BAG5	-0.0507	0.498	0.51	0.884
rs324017	NAB2	NAB2_1_gene	CTDSP2	-0.0692	0.506	0.508	0.884
rs4151680	PCDHA123	PCDHA123_2_gene	PSD2	0.065	0.499	0.509	0.884
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	SH3GL3	-0.113	0.5	0.511	0.884
rs12895055	BCL11B	BCL11B_2_gene	EVL	-0.0371	0.493	0.514	0.888
rs520843	GALNT10	GALNT10_1_gene	MFAP3	0.0751	0.518	0.515	0.889
rs9661794	DPYD	DPYD_2_gene	SNX7	0.0495	0.524	0.522	0.889
rs520843	GALNT10	GALNT10_2_gene	LARP1	-0.0482	0.488	0.521	0.889
rs12716973	KCTD13	KCTD13_3_gene	SEPHS2	0.0985	0.518	0.523	0.889
rs12716973	KCTD13	KCTD13_3_gene	TAOK2	0.125	0.518	0.524	0.889
rs7936858	LOC100507431	LOC100507431_1_gene	NFRKB	-0.0998	0.513	0.518	0.889
rs324017	NAB2	NAB2_3_gene	TSFM	-0.0654	0.512	0.523	0.889
rs6071578	PPP1R16B	PPP1R16B_3_gene	DHX35	-0.101	0.511	0.522	0.889
rs301791	RERE	RERE_1_gene	SPSB1	0.0512	0.511	0.521	0.889
rs324015	STAT6	STAT6_3_gene	LRP1	0.0628	0.528	0.523	0.889
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	SH3GL3	-0.133	0.524	0.522	0.889
rs2027349	VPS45	VPS45_3_gene	PLEKHO1	0.0663	0.521	0.516	0.889
rs10933	PBRM1	PBRM1_3_gene	DCP1A	0.0897	0.527	0.527	0.891
rs4151680	PCDHA123	PCDHA123_3_gene	SRA1	0.032	0.521	0.526	0.891
rs324015	STAT6	STAT6_2_gene	MYL6B	0.029	0.528	0.528	0.892
rs7170068	CHRNA3	CHRNA3_3_gene	TBC1D2B	-0.112	0.518	0.534	0.894
rs12716973	KCTD13	KCTD13_1_gene	FBXL19	-0.0845	0.525	0.546	0.894
rs12716973	KCTD13	KCTD13_1_gene	YPEL3	0.0641	0.515	0.536	0.894
rs12716973	KCTD13	KCTD13_1_gene	ZNF764	0.0804	0.51	0.532	0.894
rs12716973	KCTD13	KCTD13_3_gene	CTF1	0.163	0.542	0.547	0.894
rs2192932	KMT2E	KMT2E_3_gene	KMT2E	0.042	0.536	0.537	0.894
rs2192932	KMT2E	KMT2E_3_gene	RINT1	0.0749	0.545	0.546	0.894
rs3861678	LINC00637	LINC00637_3_gene	SIVA1	-0.0421	0.54	0.544	0.894
rs324017	NAB2	NAB2_2_gene	DTX3	0.0752	0.527	0.539	0.894
rs324017	NAB2	NAB2_2_gene	RNF41	-0.0671	0.523	0.535	0.894
rs324017	NAB2	NAB2_3_gene	NXPH4	-0.113	0.531	0.541	0.894
rs324017	NAB2	NAB2_3_gene	TAC3	-0.142	0.522	0.533	0.894
rs186132169	NGEF	NGEF_1_gene	GIGYF2	0.0751	0.545	0.547	0.894
rs10933	PBRM1	PBRM1_1_gene	PBRM1	-0.0657	0.547	0.545	0.894
rs10933	PBRM1	PBRM1_3_gene	DUSP7	-0.141	0.532	0.532	0.894
rs4151680	PCDHA123	PCDHA123_2_gene	NDUFA2	0.023	0.534	0.543	0.894
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHGA10	-0.0469	0.534	0.539	0.894
rs4151680	PCDHA123	PCDHA123_3_gene	PURA	0.0367	0.538	0.543	0.894
rs6071578	PPP1R16B	PPP1R16B_1_gene	DHX35	0.0459	0.546	0.545	0.894
rs324015	STAT6	STAT6_2_gene	NABP2	0.0378	0.543	0.543	0.894
rs324015	STAT6	STAT6_2_gene	PIP4K2C	-0.0985	0.535	0.535	0.894
rs2027349	VPS45	VPS45_1_gene	BOLA1	-0.166	0.536	0.541	0.894
rs4151680	PCDHA123	PCDHA123_2_gene	HARS	0.029	0.541	0.549	0.896
rs520843	GALNT10	GALNT10_2_gene	GALNT10	0.0762	0.529	0.559	0.899
rs12716973	KCTD13	KCTD13_2_gene	ASPHD1	-0.0882	0.564	0.569	0.899
rs12716973	KCTD13	KCTD13_3_gene	NFATC2IP	-0.0954	0.564	0.568	0.899
rs3861678	LINC00637	LINC00637_3_gene	APOPT1	-0.0307	0.566	0.568	0.899
rs3861678	LINC00637	LINC00637_3_gene	BAG5	0.0396	0.564	0.566	0.899
rs3861678	LINC00637	LINC00637_3_gene	INF2	-0.0565	0.553	0.556	0.899
rs324017	NAB2	NAB2_2_gene	CNPY2	-0.0483	0.541	0.553	0.899
rs324017	NAB2	NAB2_3_gene	AGAP2	-0.0919	0.557	0.566	0.899
rs324017	NAB2	NAB2_3_gene	MYL6B	-0.0352	0.559	0.568	0.899
rs186132169	NGEF	NGEF_2_gene	DGKD	0.159	0.557	0.566	0.899
rs10933	PBRM1	PBRM1_1_gene	CACNA1D	-0.114	0.572	0.569	0.899
rs10933	PBRM1	PBRM1_2_gene	GLT8D1	0.0785	0.559	0.566	0.899
rs4151680	PCDHA123	PCDHA123_1_gene	TAF7	0.0276	0.566	0.568	0.899
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHGC3	0.0645	0.549	0.557	0.899
rs6071578	PPP1R16B	PPP1R16B_2_gene	TTI1	-0.0584	0.576	0.569	0.899
rs301791	RERE	RERE_1_gene	CAMTA1	0.0268	0.548	0.556	0.899
rs324015	STAT6	STAT6_3_gene	PAN2	-0.0622	0.568	0.562	0.899
rs324015	STAT6	STAT6_3_gene	ZBTB39	-0.0958	0.563	0.556	0.899
rs9882911	TRANK1	TRANK1_2_gene	LRRFIP2	0.0585	0.574	0.56	0.899
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	AKAP13	-0.11	0.543	0.562	0.899
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	GOLGA6L4	-0.13	0.533	0.553	0.899
rs2027349	VPS45	VPS45_1_gene	SF3B4	0.0628	0.554	0.559	0.899
rs12716973	KCTD13	KCTD13_3_gene	DCTPP1	-0.0792	0.567	0.57	0.899
rs324017	NAB2	NAB2_1_gene	PIP4K2C	-0.0635	0.573	0.573	0.903
rs324017	NAB2	NAB2_3_gene	DCTN2	-0.0305	0.566	0.575	0.904
rs12716973	KCTD13	KCTD13_3_gene	ZNF764	0.106	0.572	0.576	0.904
rs7170068	CHRNA3	CHRNA3_2_gene	CIB2	-0.0587	0.577	0.582	0.905
rs324017	NAB2	NAB2_2_gene	ARHGEF25	-0.0646	0.572	0.581	0.905
rs10933	PBRM1	PBRM1_1_gene	RFT1	0.106	0.585	0.581	0.905
rs4151680	PCDHA123	PCDHA123_1_gene	PFDN1	-0.028	0.577	0.579	0.905
rs4151680	PCDHA123	PCDHA123_2_gene	RELL2	0.0459	0.571	0.578	0.905
rs324015	STAT6	STAT6_3_gene	DCTN2	0.0236	0.587	0.579	0.905
rs9882911	TRANK1	TRANK1_1_gene	ITGA9	0.446	0.568	0.581	0.905
rs10933	PBRM1	PBRM1_3_gene	RFT1	-0.101	0.588	0.585	0.908
rs520843	GALNT10	GALNT10_3_gene	SAP30L	0.0605	0.574	0.586	0.908
rs324015	STAT6	STAT6_1_gene	AGAP2	-0.0582	0.588	0.587	0.908
rs12895055	BCL11B	BCL11B_1_gene	EVL	0.0483	0.581	0.59	0.909
rs12716973	KCTD13	KCTD13_1_gene	SPNS1	-0.0602	0.574	0.592	0.909
rs12716973	KCTD13	KCTD13_2_gene	DOC2A	-0.0852	0.587	0.591	0.909
rs324017	NAB2	NAB2_3_gene	PIP4K2C	0.0871	0.584	0.592	0.909
rs10933	PBRM1	PBRM1_3_gene	PRKCD	0.0801	0.592	0.589	0.909
rs2027349	VPS45	VPS45_1_gene	ENSA	0.0493	0.589	0.592	0.909
rs7170068	CHRNA3	CHRNA3_2_gene	TMED3	0.0552	0.591	0.595	0.913
rs12716973	KCTD13	KCTD13_1_gene	PRRT2	-0.0698	0.583	0.601	0.914
rs324017	NAB2	NAB2_1_gene	R3HDM2	0.0459	0.601	0.6	0.914
rs324017	NAB2	NAB2_3_gene	ARHGEF25	-0.118	0.592	0.599	0.914
rs324015	STAT6	STAT6_2_gene	NDUFA4L2	-0.0404	0.603	0.601	0.914
rs9882911	TRANK1	TRANK1_1_gene	STAC	-0.379	0.585	0.598	0.914
rs2027349	VPS45	VPS45_2_gene	TARS2	-0.0365	0.599	0.598	0.914
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ALPK3	0.104	0.609	0.602	0.915
rs324017	NAB2	NAB2_1_gene	TSPAN31	-0.0494	0.607	0.606	0.916
rs324017	NAB2	NAB2_2_gene	SMARCC2	0.0487	0.597	0.605	0.916
rs186132169	NGEF	NGEF_1_gene	DGKD	-0.0954	0.608	0.607	0.916
rs10933	PBRM1	PBRM1_1_gene	TWF2	0.0742	0.611	0.606	0.916
rs324017	NAB2	NAB2_1_gene	METTL1	0.0576	0.609	0.608	0.917
rs12895055	BCL11B	BCL11B_1_gene	CYP46A1	-0.0878	0.604	0.612	0.917
rs3861678	LINC00637	LINC00637_2_gene	SIVA1	-0.0415	0.613	0.614	0.917
rs10933	PBRM1	PBRM1_3_gene	BAP1	0.0877	0.615	0.611	0.917
rs6071578	PPP1R16B	PPP1R16B_2_gene	VSTM2L	0.0613	0.623	0.614	0.917
rs301791	RERE	RERE_2_gene	H6PD	0.0624	0.598	0.612	0.917
rs11633075	UBE2Q2P1	UBE2Q2P1_3_gene	ZSCAN2	0.0772	0.608	0.612	0.917
rs2027349	VPS45	VPS45_1_gene	SETDB1	0.0809	0.612	0.613	0.917
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHGA10	0.048	0.617	0.618	0.922
rs7170068	CHRNA3	CHRNA3_2_gene	IDH3A	-0.0639	0.618	0.621	0.924
rs3861678	LINC00637	LINC00637_3_gene	EIF5	0.0234	0.625	0.624	0.924
rs324017	NAB2	NAB2_1_gene	CDK4	-0.0455	0.626	0.624	0.924
rs6071578	PPP1R16B	PPP1R16B_3_gene	TTI1	-0.0531	0.618	0.623	0.924
rs324015	STAT6	STAT6_1_gene	ZBTB39	-0.0467	0.625	0.622	0.924
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	SEC11A	0.0521	0.608	0.623	0.924
rs12716973	KCTD13	KCTD13_3_gene	KCTD13	-0.0931	0.625	0.626	0.926
rs7148456	BAG5	BAG5_3_gene	KLC1	0.0495	0.633	0.631	0.926
rs12716973	KCTD13	KCTD13_1_gene	KCTD13	0.0577	0.622	0.636	0.926
rs12716973	KCTD13	KCTD13_2_gene	FBRS	0.0661	0.637	0.638	0.926
rs12716973	KCTD13	KCTD13_3_gene	CORO1A	0.0959	0.633	0.634	0.926
rs3861678	LINC00637	LINC00637_3_gene	TMEM179	-0.0583	0.633	0.632	0.926
rs17200916	LOC105376975	LOC105376975_1_gene	PLCL2	-0.0547	0.643	0.635	0.926
rs324017	NAB2	NAB2_2_gene	ANKRD52	-0.061	0.624	0.631	0.926
rs324017	NAB2	NAB2_3_gene	ANKRD52	-0.0573	0.629	0.634	0.926
rs324017	NAB2	NAB2_3_gene	KIF5A	0.0659	0.632	0.637	0.926
rs10933	PBRM1	PBRM1_1_gene	PRKCD	-0.0578	0.645	0.639	0.926
rs10933	PBRM1	PBRM1_2_gene	ABHD14A	-0.0676	0.636	0.639	0.926
rs6071578	PPP1R16B	PPP1R16B_1_gene	RPRD1B	-0.0509	0.643	0.638	0.926
rs324015	STAT6	STAT6_1_gene	B4GALNT1	-0.058	0.641	0.638	0.926
rs324015	STAT6	STAT6_3_gene	TSPAN31	0.0436	0.639	0.632	0.926
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	GOLGA6L4	0.106	0.641	0.634	0.926
rs324015	STAT6	STAT6_1_gene	DTX3	-0.0485	0.644	0.641	0.927
rs7148456	BAG5	BAG5_2_gene	TRMT61A	0.0425	0.639	0.642	0.927
rs12895055	BCL11B	BCL11B_2_gene	EML1	-0.0671	0.631	0.643	0.927
rs7170068	CHRNA3	CHRNA3_1_gene	ADAMTS7	0.121	0.652	0.65	0.928
rs12716973	KCTD13	KCTD13_2_gene	HIRIP3	0.0676	0.644	0.645	0.928
rs12716973	KCTD13	KCTD13_3_gene	TMEM219	0.0585	0.652	0.652	0.928
rs2192932	KMT2E	KMT2E_3_gene	ATXN7L1	0.0717	0.648	0.646	0.928
rs3861678	LINC00637	LINC00637_2_gene	TRMT61A	0.0459	0.651	0.65	0.928
rs1198588	miR137	miR137_3_gene	MIR137HG	-0.0548	0.647	0.649	0.928
rs10933	PBRM1	PBRM1_2_gene	GLYCTK	0.0993	0.649	0.652	0.928
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB16	-0.0621	0.648	0.648	0.928
rs4151680	PCDHA123	PCDHA123_2_gene	PURA	0.0305	0.643	0.647	0.928
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB16	0.0415	0.644	0.644	0.928
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	PDE8A	0.122	0.66	0.652	0.928
rs3861678	LINC00637	LINC00637_3_gene	TRMT61A	-0.0387	0.655	0.654	0.929
rs12716973	KCTD13	KCTD13_1_gene	INO80E	-0.0438	0.644	0.658	0.93
rs7936858	LOC100507431	LOC100507431_3_gene	SNX19	0.0517	0.657	0.656	0.93
rs4151680	PCDHA123	PCDHA123_2_gene	HDAC3	0.0255	0.653	0.656	0.93
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB15	-0.0273	0.66	0.658	0.93
rs324015	STAT6	STAT6_3_gene	SPRYD4	-0.0431	0.667	0.659	0.93
rs7148456	BAG5	BAG5_1_gene	BAG5	0.037	0.668	0.674	0.931
rs7148456	BAG5	BAG5_1_gene	ZFYVE21	-0.0401	0.668	0.674	0.931
rs12895055	BCL11B	BCL11B_2_gene	CCDC85C	-0.0434	0.658	0.667	0.931
rs7170068	CHRNA3	CHRNA3_1_gene	IDH3A	-0.0731	0.663	0.662	0.931
rs12716973	KCTD13	KCTD13_1_gene	SEZ6L2	0.045	0.656	0.669	0.931
rs12716973	KCTD13	KCTD13_2_gene	TBC1D10B	-0.048	0.673	0.673	0.931
rs12716973	KCTD13	KCTD13_2_gene	ZNF747	-0.0761	0.662	0.662	0.931
rs12716973	KCTD13	KCTD13_3_gene	PRRT2	-0.0888	0.672	0.671	0.931
rs2192932	KMT2E	KMT2E_2_gene	CDHR3	-0.0823	0.673	0.672	0.931
rs3861678	LINC00637	LINC00637_1_gene	CKB	-0.0311	0.66	0.663	0.931
rs17200916	LOC105376975	LOC105376975_2_gene	PLCL2	0.0412	0.656	0.664	0.931
rs324017	NAB2	NAB2_3_gene	CDK4	0.0494	0.66	0.664	0.931
rs10933	PBRM1	PBRM1_1_gene	PHF7	-0.0738	0.678	0.67	0.931
rs4151680	PCDHA123	PCDHA123_2_gene	NRG2	-0.0549	0.669	0.672	0.931
rs301791	RERE	RERE_3_gene	SPSB1	0.0483	0.683	0.673	0.931
rs324015	STAT6	STAT6_3_gene	METTL1	-0.0433	0.677	0.668	0.931
rs324015	STAT6	STAT6_3_gene	NDUFA4L2	0.0367	0.679	0.67	0.931
rs7170068	CHRNA3	CHRNA3_2_gene	LINGO1	0.0653	0.675	0.676	0.931
rs12716973	KCTD13	KCTD13_2_gene	YPEL3	-0.0518	0.677	0.676	0.931
rs301791	RERE	RERE_1_gene	ERRFI1	-0.0309	0.675	0.676	0.931
rs324015	STAT6	STAT6_2_gene	B4GALNT1	-0.041	0.685	0.68	0.935
rs324017	NAB2	NAB2_2_gene	B4GALNT1	-0.057	0.681	0.685	0.94
rs10933	PBRM1	PBRM1_1_gene	ABHD14B	0.107	0.694	0.686	0.941
rs2027349	VPS45	VPS45_1_gene	SV2A	-0.0659	0.689	0.687	0.941
rs7170068	CHRNA3	CHRNA3_3_gene	ADAMTS7	-0.103	0.685	0.691	0.941
rs3861678	LINC00637	LINC00637_3_gene	MARK3	-0.0214	0.694	0.691	0.941
rs1198588	miR137	miR137_1_gene	SNX7	0.0395	0.697	0.691	0.941
rs324017	NAB2	NAB2_1_gene	CNPY2	-0.026	0.697	0.692	0.941
rs2027349	VPS45	VPS45_1_gene	MCL1	-0.0478	0.692	0.69	0.941
rs301791	RERE	RERE_3_gene	PARK7	0.0169	0.704	0.693	0.943
rs7170068	CHRNA3	CHRNA3_3_gene	CTSH	0.0685	0.692	0.698	0.945
rs324017	NAB2	NAB2_3_gene	RNF41	0.0431	0.695	0.698	0.945
rs324015	STAT6	STAT6_3_gene	MBD6	-0.0647	0.708	0.698	0.945
rs520843	GALNT10	GALNT10_1_gene	GRIA1	-0.0413	0.711	0.701	0.948
rs324017	NAB2	NAB2_3_gene	MARS	-0.0371	0.699	0.701	0.948
rs12716973	KCTD13	KCTD13_2_gene	ZNF689	-0.0822	0.705	0.703	0.948
rs10933	PBRM1	PBRM1_2_gene	GNL3	-0.0488	0.71	0.71	0.955
rs324015	STAT6	STAT6_1_gene	ATP23	0.0654	0.715	0.71	0.955
rs2192932	KMT2E	KMT2E_1_gene	KMT2E	-0.0467	0.708	0.712	0.956
rs324015	STAT6	STAT6_2_gene	ARHGEF25	0.0565	0.718	0.712	0.956
rs17200916	LOC105376975	LOC105376975_2_gene	SATB1	-0.0329	0.713	0.717	0.96
rs324017	NAB2	NAB2_1_gene	PA2G4	-0.0202	0.724	0.717	0.96
rs324017	NAB2	NAB2_2_gene	DDIT3	-0.0482	0.715	0.717	0.96
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	WDR73	0.0591	0.71	0.718	0.96
rs10933	PBRM1	PBRM1_3_gene	GLT8D1	-0.0512	0.728	0.721	0.962
rs4151680	PCDHA123	PCDHA123_3_gene	HDAC3	0.0181	0.726	0.721	0.962
rs7148456	BAG5	BAG5_1_gene	RCOR1	0.0346	0.751	0.751	0.964
rs7170068	CHRNA3	CHRNA3_1_gene	LINGO1	0.0667	0.747	0.742	0.964
rs7170068	CHRNA3	CHRNA3_3_gene	WDR61	-0.0329	0.751	0.753	0.964
rs520843	GALNT10	GALNT10_3_gene	GRIA1	-0.0314	0.755	0.755	0.964
rs12716973	KCTD13	KCTD13_1_gene	CCDC189	0.0404	0.732	0.739	0.964
rs12716973	KCTD13	KCTD13_1_gene	CDIPT	-0.0295	0.746	0.752	0.964
rs12716973	KCTD13	KCTD13_1_gene	DCTPP1	-0.0267	0.742	0.748	0.964
rs12716973	KCTD13	KCTD13_1_gene	MVP	-0.0428	0.724	0.732	0.964
rs12716973	KCTD13	KCTD13_1_gene	ZNF768	-0.0322	0.747	0.752	0.964
rs12716973	KCTD13	KCTD13_1_gene	ZNF785	-0.0473	0.74	0.746	0.964
rs12716973	KCTD13	KCTD13_2_gene	KIF22	0.0495	0.744	0.741	0.964
rs12716973	KCTD13	KCTD13_2_gene	MAZ	0.0205	0.76	0.756	0.964
rs2192932	KMT2E	KMT2E_1_gene	ATXN7L1	0.0958	0.737	0.739	0.964
rs2192932	KMT2E	KMT2E_1_gene	PUS7	0.0754	0.751	0.752	0.964
rs2192932	KMT2E	KMT2E_1_gene	RINT1	-0.0659	0.756	0.757	0.964
rs2192932	KMT2E	KMT2E_2_gene	KMT2E	-0.023	0.73	0.728	0.964
rs2192932	KMT2E	KMT2E_2_gene	PUS7	-0.0584	0.737	0.735	0.964
rs3861678	LINC00637	LINC00637_2_gene	BAG5	-0.0281	0.733	0.729	0.964
rs324017	NAB2	NAB2_1_gene	AVIL	0.049	0.748	0.74	0.964
rs324017	NAB2	NAB2_2_gene	LRP1	-0.0397	0.743	0.744	0.964
rs324017	NAB2	NAB2_2_gene	NXPH4	-0.0562	0.731	0.732	0.964
rs324017	NAB2	NAB2_3_gene	CTDSP2	0.0419	0.746	0.745	0.964
rs186132169	NGEF	NGEF_2_gene	TIGD1	-0.261	0.727	0.727	0.964
rs186132169	NGEF	NGEF_3_gene	TIGD1	-0.071	0.747	0.749	0.964
rs10933	PBRM1	PBRM1_1_gene	DCP1A	0.0427	0.761	0.75	0.964
rs10933	PBRM1	PBRM1_1_gene	SFMBT1	-0.0645	0.753	0.743	0.964
rs10933	PBRM1	PBRM1_1_gene	TEX264	0.0452	0.765	0.754	0.964
rs10933	PBRM1	PBRM1_3_gene	RPL29	-0.0313	0.749	0.741	0.964
rs10933	PBRM1	PBRM1_3_gene	TWF2	-0.0496	0.743	0.736	0.964
rs4151680	PCDHA123	PCDHA123_3_gene	NRG2	0.0326	0.758	0.753	0.964
rs6071578	PPP1R16B	PPP1R16B_2_gene	SLC32A1	-0.0432	0.747	0.736	0.964
rs6071578	PPP1R16B	PPP1R16B_3_gene	RALGAPB	-0.0317	0.75	0.749	0.964
rs324015	STAT6	STAT6_1_gene	KIF5A	0.0366	0.759	0.752	0.964
rs324015	STAT6	STAT6_1_gene	SMARCC2	-0.0245	0.764	0.757	0.964
rs324015	STAT6	STAT6_3_gene	PA2G4	0.0177	0.75	0.739	0.964
rs324015	STAT6	STAT6_3_gene	R3HDM2	0.0268	0.74	0.729	0.964
rs324015	STAT6	STAT6_3_gene	TSFM	0.03	0.74	0.729	0.964
rs9882911	TRANK1	TRANK1_3_gene	STAC	-0.011	0.752	0.748	0.964
rs12716973	KCTD13	KCTD13_3_gene	INO80E	-0.0491	0.764	0.76	0.965
rs12716973	KCTD13	KCTD13_3_gene	QPRT	0.0527	0.764	0.76	0.965
rs17200916	LOC105376975	LOC105376975_1_gene	TBC1D5	0.0286	0.769	0.759	0.965
rs2027349	VPS45	VPS45_3_gene	GOLPH3L	-0.0496	0.772	0.761	0.965
rs324017	NAB2	NAB2_1_gene	ZC3H10	-0.0383	0.773	0.764	0.968
rs4151680	PCDHA123	PCDHA123_3_gene	SLC35A4	-0.018	0.771	0.765	0.968
rs324017	NAB2	NAB2_2_gene	PIP4K2C	0.0358	0.767	0.766	0.969
rs3861678	LINC00637	LINC00637_1_gene	AKT1	-0.0185	0.77	0.767	0.969
rs324017	NAB2	NAB2_2_gene	BAZ2A	-0.0303	0.77	0.769	0.97
rs7148456	BAG5	BAG5_2_gene	CDC42BPB	-0.0188	0.786	0.78	0.973
rs9661794	DPYD	DPYD_3_gene	SNX7	-0.0292	0.79	0.782	0.973
rs12716973	KCTD13	KCTD13_1_gene	KIF22	-0.034	0.771	0.774	0.973
rs12716973	KCTD13	KCTD13_3_gene	ZNF785	0.0561	0.785	0.78	0.973
rs324017	NAB2	NAB2_3_gene	MYL6	0.0226	0.78	0.777	0.973
rs10933	PBRM1	PBRM1_2_gene	RFT1	0.0476	0.784	0.779	0.973
rs4151680	PCDHA123	PCDHA123_2_gene	ANKHD1	0.0318	0.777	0.773	0.973
rs4151680	PCDHA123	PCDHA123_3_gene	IK	0.00946	0.787	0.78	0.973
rs301791	RERE	RERE_1_gene	SLC45A1	0.0248	0.785	0.782	0.973
rs301791	RERE	RERE_2_gene	RERE	0.0183	0.778	0.78	0.973
rs324015	STAT6	STAT6_1_gene	STAT6	0.0375	0.785	0.777	0.973
rs2027349	VPS45	VPS45_3_gene	MRPS21	-0.0207	0.786	0.775	0.973
rs324017	NAB2	NAB2_2_gene	COQ10A	0.0374	0.784	0.783	0.973
rs7148456	BAG5	BAG5_1_gene	APOPT1	0.0344	0.817	0.813	0.973
rs7148456	BAG5	BAG5_1_gene	CKB	-0.0187	0.815	0.811	0.973
rs7148456	BAG5	BAG5_2_gene	MARK3	0.0139	0.814	0.807	0.973
rs7170068	CHRNA3	CHRNA3_1_gene	CIB2	-0.0331	0.808	0.801	0.973
rs7170068	CHRNA3	CHRNA3_1_gene	PSMA4	0.0255	0.791	0.784	0.973
rs7170068	CHRNA3	CHRNA3_3_gene	MORF4L1	-0.0147	0.787	0.787	0.973
rs520843	GALNT10	GALNT10_2_gene	CNOT8	-0.032	0.813	0.818	0.973
rs12716973	KCTD13	KCTD13_1_gene	FBRS	-0.0259	0.803	0.804	0.973
rs12716973	KCTD13	KCTD13_1_gene	MAPK3	0.0197	0.816	0.816	0.973
rs12716973	KCTD13	KCTD13_1_gene	NFATC2IP	-0.0248	0.806	0.807	0.973
rs12716973	KCTD13	KCTD13_1_gene	TAOK2	-0.0383	0.786	0.788	0.973
rs12716973	KCTD13	KCTD13_1_gene	TBC1D10B	-0.0202	0.819	0.818	0.973
rs12716973	KCTD13	KCTD13_2_gene	DCTPP1	0.0244	0.813	0.807	0.973
rs12716973	KCTD13	KCTD13_2_gene	FAM57B	0.0355	0.819	0.812	0.973
rs12716973	KCTD13	KCTD13_3_gene	BCL7C	-0.0337	0.811	0.804	0.973
rs12716973	KCTD13	KCTD13_3_gene	TBC1D10B	0.0366	0.814	0.808	0.973
rs3861678	LINC00637	LINC00637_1_gene	APOPT1	-0.0138	0.813	0.808	0.973
rs7936858	LOC100507431	LOC100507431_2_gene	APLP2	-0.0189	0.813	0.804	0.973
rs7936858	LOC100507431	LOC100507431_2_gene	ZBTB44	0.0296	0.818	0.808	0.973
rs1198588	miR137	miR137_3_gene	SNX7	-0.0227	0.815	0.81	0.973
rs324017	NAB2	NAB2_1_gene	MARS	-0.0181	0.823	0.813	0.973
rs324017	NAB2	NAB2_2_gene	SPRYD4	0.0409	0.802	0.799	0.973
rs324017	NAB2	NAB2_2_gene	STAT2	0.0288	0.791	0.79	0.973
rs324017	NAB2	NAB2_2_gene	TSFM	-0.0236	0.799	0.797	0.973
rs324017	NAB2	NAB2_3_gene	BAZ2A	-0.0236	0.823	0.818	0.973
rs186132169	NGEF	NGEF_2_gene	ATG16L1	0.116	0.805	0.801	0.973
rs4151680	PCDHA123	PCDHA123_1_gene	NRG2	0.0187	0.816	0.809	0.973
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA11	-0.0188	0.819	0.811	0.973
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB14	0.0277	0.809	0.801	0.973
rs6071578	PPP1R16B	PPP1R16B_3_gene	CTNNBL1	0.0201	0.8	0.796	0.973
rs301791	RERE	RERE_2_gene	TNFRSF9	0.0427	0.801	0.8	0.973
rs324015	STAT6	STAT6_1_gene	NAB2	0.0315	0.795	0.787	0.973
rs324015	STAT6	STAT6_2_gene	COQ10A	0.0243	0.827	0.818	0.973
rs324015	STAT6	STAT6_2_gene	CS	0.019	0.814	0.805	0.973
rs324015	STAT6	STAT6_3_gene	SHMT2	0.0256	0.804	0.793	0.973
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	AKAP13	-0.0393	0.823	0.811	0.973
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ALPK3	-0.0495	0.816	0.816	0.973
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	SH3GL3	0.123	0.79	0.792	0.973
rs2027349	VPS45	VPS45_2_gene	SETDB1	0.0247	0.801	0.791	0.973
rs2027349	VPS45	VPS45_3_gene	ENSA	0.0231	0.802	0.79	0.973
rs10933	PBRM1	PBRM1_3_gene	ABHD14B	0.1	0.832	0.822	0.974
rs324015	STAT6	STAT6_2_gene	ANKRD52	0.019	0.83	0.821	0.974
rs324015	STAT6	STAT6_2_gene	PRIM1	0.0245	0.833	0.823	0.974
rs2027349	VPS45	VPS45_1_gene	OTUD7B	-0.0329	0.831	0.823	0.974
rs2027349	VPS45	VPS45_2_gene	GOLPH3L	0.0185	0.835	0.824	0.975
rs301791	RERE	RERE_3_gene	VAMP3	-0.024	0.84	0.828	0.977
rs324015	STAT6	STAT6_2_gene	PAN2	-0.0142	0.836	0.827	0.977
rs7148456	BAG5	BAG5_3_gene	CDC42BPB	-0.0166	0.876	0.865	0.977
rs520843	GALNT10	GALNT10_1_gene	CNOT8	-0.0144	0.859	0.846	0.977
rs520843	GALNT10	GALNT10_1_gene	GALNT10	-0.0174	0.851	0.839	0.977
rs12716973	KCTD13	KCTD13_1_gene	CORO1A	0.0165	0.873	0.868	0.977
rs12716973	KCTD13	KCTD13_1_gene	HIRIP3	-0.0222	0.842	0.839	0.977
rs12716973	KCTD13	KCTD13_2_gene	NFATC2IP	-0.0238	0.851	0.843	0.977
rs12716973	KCTD13	KCTD13_2_gene	ZNF48	-0.0206	0.869	0.861	0.977
rs12716973	KCTD13	KCTD13_3_gene	ASPHD1	0.0395	0.852	0.845	0.977
rs12716973	KCTD13	KCTD13_3_gene	FBXL19	-0.0216	0.867	0.859	0.977
rs12716973	KCTD13	KCTD13_3_gene	PHKG2	0.0308	0.864	0.856	0.977
rs2192932	KMT2E	KMT2E_2_gene	ORC5	-0.014	0.877	0.868	0.977
rs2192932	KMT2E	KMT2E_2_gene	RINT1	-0.0185	0.868	0.859	0.977
rs2192932	KMT2E	KMT2E_3_gene	ORC5	0.0189	0.861	0.85	0.977
rs3861678	LINC00637	LINC00637_3_gene	PPP1R13B	0.0189	0.874	0.863	0.977
rs7936858	LOC100507431	LOC100507431_1_gene	SNX19	-0.0295	0.843	0.835	0.977
rs17200916	LOC105376975	LOC105376975_1_gene	SATB1	0.021	0.865	0.852	0.977
rs324017	NAB2	NAB2_1_gene	NAB2	-0.0149	0.877	0.866	0.977
rs324017	NAB2	NAB2_2_gene	DCTN2	-0.0106	0.842	0.837	0.977
rs324017	NAB2	NAB2_2_gene	R3HDM2	0.018	0.864	0.858	0.977
rs324017	NAB2	NAB2_3_gene	ESYT1	0.0393	0.86	0.853	0.977
rs324017	NAB2	NAB2_3_gene	NABP2	0.0148	0.856	0.85	0.977
rs324017	NAB2	NAB2_3_gene	SHMT2	-0.0214	0.865	0.859	0.977
rs186132169	NGEF	NGEF_2_gene	EIF4E2	-0.0342	0.868	0.861	0.977
rs186132169	NGEF	NGEF_3_gene	DIS3L2	0.0386	0.854	0.849	0.977
rs10933	PBRM1	PBRM1_2_gene	NISCH	0.0269	0.855	0.847	0.977
rs10933	PBRM1	PBRM1_2_gene	RRP9	-0.0237	0.877	0.868	0.977
rs10933	PBRM1	PBRM1_2_gene	TEX264	0.0274	0.849	0.841	0.977
rs10933	PBRM1	PBRM1_3_gene	SMIM4	-0.0273	0.876	0.865	0.977
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB15	-0.0218	0.871	0.862	0.977
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHGA7	0.0146	0.874	0.866	0.977
rs4151680	PCDHA123	PCDHA123_2_gene	ZMAT2	0.00762	0.872	0.864	0.977
rs4151680	PCDHA123	PCDHA123_3_gene	DIAPH1	-0.013	0.851	0.842	0.977
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB9	0.0272	0.856	0.847	0.977
rs4151680	PCDHA123	PCDHA123_3_gene	PSD2	0.0109	0.873	0.863	0.977
rs6071578	PPP1R16B	PPP1R16B_2_gene	SNHG11	-0.0149	0.868	0.855	0.977
rs6071578	PPP1R16B	PPP1R16B_3_gene	RPRD1B	0.0207	0.837	0.831	0.977
rs301791	RERE	RERE_3_gene	ERRFI1	-0.0216	0.855	0.842	0.977
rs324015	STAT6	STAT6_2_gene	BAZ2A	-0.0171	0.839	0.83	0.977
rs324015	STAT6	STAT6_2_gene	MARCH9	0.0187	0.839	0.83	0.977
rs324015	STAT6	STAT6_3_gene	STAT2	-0.0256	0.871	0.858	0.977
rs324015	STAT6	STAT6_3_gene	TIMELESS	0.021	0.882	0.868	0.977
rs9882911	TRANK1	TRANK1_3_gene	EPM2AIP1	-0.00903	0.859	0.85	0.977
rs11633075	UBE2Q2P1	UBE2Q2P1_1_gene	ZSCAN2	0.0379	0.875	0.862	0.977
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	ZNF592	-0.0348	0.834	0.833	0.977
rs2027349	VPS45	VPS45_1_gene	C1orf54	0.0385	0.846	0.837	0.977
rs2027349	VPS45	VPS45_1_gene	CIART	0.0135	0.865	0.856	0.977
rs324017	NAB2	NAB2_3_gene	OS9	0.00978	0.878	0.87	0.978
rs12895055	BCL11B	BCL11B_1_gene	CCDC85C	-0.0216	0.882	0.874	0.979
rs3861678	LINC00637	LINC00637_2_gene	XRCC3	-0.0365	0.887	0.877	0.979
rs324017	NAB2	NAB2_3_gene	PRIM1	0.0229	0.882	0.875	0.979
rs324017	NAB2	NAB2_3_gene	RPL41	0.0106	0.885	0.877	0.979
rs186132169	NGEF	NGEF_2_gene	DIS3L2	0.0746	0.881	0.874	0.979
rs10933	PBRM1	PBRM1_2_gene	GRM2	0.0315	0.886	0.877	0.979
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA10	0.0121	0.888	0.878	0.979
rs4151680	PCDHA123	PCDHA123_1_gene	PSD2	-0.0227	0.888	0.878	0.979
rs7170068	CHRNA3	CHRNA3_3_gene	TMED3	-0.0144	0.906	0.898	0.982
rs520843	GALNT10	GALNT10_2_gene	MFAP3	-0.0579	0.899	0.895	0.982
rs520843	GALNT10	GALNT10_2_gene	MRPL22	-0.0099	0.887	0.884	0.982
rs12716973	KCTD13	KCTD13_2_gene	ZNF771	-0.0141	0.912	0.902	0.982
rs12716973	KCTD13	KCTD13_3_gene	SEZ6L2	-0.0211	0.905	0.895	0.982
rs3861678	LINC00637	LINC00637_1_gene	TMEM179	-0.038	0.892	0.883	0.982
rs3861678	LINC00637	LINC00637_2_gene	MARK3	0.0077	0.907	0.897	0.982
rs324017	NAB2	NAB2_1_gene	NACA	0.00457	0.906	0.894	0.982
rs324017	NAB2	NAB2_1_gene	STAT6	0.0244	0.912	0.9	0.982
rs324017	NAB2	NAB2_2_gene	CS	-0.0123	0.907	0.899	0.982
rs324017	NAB2	NAB2_2_gene	NABP2	-0.00981	0.901	0.893	0.982
rs324017	NAB2	NAB2_3_gene	CS	0.0141	0.899	0.89	0.982
rs10933	PBRM1	PBRM1_1_gene	ALAS1	0.0174	0.91	0.897	0.982
rs10933	PBRM1	PBRM1_1_gene	SMIM4	0.0195	0.906	0.893	0.982
rs10933	PBRM1	PBRM1_3_gene	SPCS1	0.01	0.907	0.896	0.982
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHGB6	0.00966	0.912	0.902	0.982
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHA11	0.00625	0.896	0.885	0.982
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB2	0.00761	0.9	0.89	0.982
rs301791	RERE	RERE_1_gene	RERE	0.00577	0.909	0.9	0.982
rs301791	RERE	RERE_2_gene	ERRFI1	-0.0119	0.91	0.903	0.982
rs301791	RERE	RERE_2_gene	VAMP3	0.012	0.902	0.894	0.982
rs324015	STAT6	STAT6_3_gene	CDK4	0.0102	0.913	0.9	0.982
rs324015	STAT6	STAT6_3_gene	DDIT3	-0.014	0.908	0.896	0.982
rs324015	STAT6	STAT6_3_gene	RNF41	0.0105	0.9	0.887	0.982
rs7148456	BAG5	BAG5_1_gene	PPP1R13B	0.00986	0.922	0.913	0.986
rs12895055	BCL11B	BCL11B_3_gene	EML1	0.0117	0.927	0.919	0.986
rs520843	GALNT10	GALNT10_3_gene	CNOT8	0.0198	0.926	0.917	0.986
rs12716973	KCTD13	KCTD13_1_gene	BOLA2B	0.0237	0.928	0.92	0.986
rs2192932	KMT2E	KMT2E_3_gene	PUS7	0.0347	0.926	0.915	0.986
rs17200916	LOC105376975	LOC105376975_3_gene	PLCL2	0.0137	0.932	0.92	0.986
rs1198588	miR137	miR137_2_gene	SNX7	0.0121	0.919	0.909	0.986
rs324017	NAB2	NAB2_1_gene	MBD6	-0.00842	0.93	0.918	0.986
rs324017	NAB2	NAB2_1_gene	TSFM	-0.00727	0.929	0.917	0.986
rs10933	PBRM1	PBRM1_1_gene	BAP1	-0.0243	0.932	0.92	0.986
rs10933	PBRM1	PBRM1_1_gene	NEK4	-0.0192	0.926	0.914	0.986
rs10933	PBRM1	PBRM1_2_gene	PRKCD	0.0385	0.927	0.917	0.986
rs4151680	PCDHA123	PCDHA123_3_gene	ANKHD1	0.028	0.924	0.913	0.986
rs324015	STAT6	STAT6_1_gene	MBD6	-0.00957	0.921	0.909	0.986
rs324015	STAT6	STAT6_2_gene	PTGES3	-0.00439	0.92	0.908	0.986
rs2027349	VPS45	VPS45_1_gene	HIST2H2BE	0.0398	0.929	0.919	0.986
rs7170068	CHRNA3	CHRNA3_1_gene	WDR61	-0.0103	0.931	0.921	0.986
rs12716973	KCTD13	KCTD13_3_gene	RNF40	-0.0126	0.932	0.922	0.986
rs7148456	BAG5	BAG5_1_gene	KLC1	-0.00608	0.936	0.927	0.986
rs17200916	LOC105376975	LOC105376975_3_gene	TBC1D5	0.00969	0.94	0.929	0.986
rs324017	NAB2	NAB2_3_gene	DTX3	0.00957	0.938	0.929	0.986
rs10933	PBRM1	PBRM1_3_gene	PHF7	-0.0623	0.935	0.924	0.986
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHB10	-0.0281	0.936	0.927	0.986
rs4151680	PCDHA123	PCDHA123_2_gene	TAF7	0.00304	0.94	0.931	0.986
rs4151680	PCDHA123	PCDHA123_3_gene	NDUFA2	0.00262	0.938	0.928	0.986
rs301791	RERE	RERE_3_gene	ENO1	0.0052	0.942	0.93	0.986
rs2027349	VPS45	VPS45_2_gene	OTUD7B	0.00512	0.942	0.932	0.986
rs2027349	VPS45	VPS45_3_gene	C1orf56	0.0124	0.939	0.927	0.986
rs324015	STAT6	STAT6_3_gene	CS	0.0066	0.943	0.933	0.986
rs7148456	BAG5	BAG5_2_gene	PPP1R13B	0.036	0.962	0.955	0.987
rs520843	GALNT10	GALNT10_3_gene	GEMIN5	0.00404	0.95	0.941	0.987
rs12716973	KCTD13	KCTD13_2_gene	PRR14	0.0176	0.959	0.951	0.987
rs3861678	LINC00637	LINC00637_1_gene	XRCC3	-0.00316	0.974	0.968	0.987
rs3861678	LINC00637	LINC00637_2_gene	TMEM179	0.00872	0.971	0.965	0.987
rs1198588	miR137	miR137_1_gene	PLPPR5	0.00246	0.956	0.947	0.987
rs1198588	miR137	miR137_2_gene	MIR137HG	-0.0122	0.959	0.952	0.987
rs324017	NAB2	NAB2_1_gene	DDIT3	0.00441	0.969	0.961	0.987
rs324017	NAB2	NAB2_1_gene	DTX3	-0.00235	0.97	0.963	0.987
rs324017	NAB2	NAB2_1_gene	KIF5A	-0.0055	0.963	0.955	0.987
rs324017	NAB2	NAB2_3_gene	NACA	0.00246	0.957	0.95	0.987
rs324017	NAB2	NAB2_3_gene	PA2G4	-0.00384	0.955	0.948	0.987
rs324017	NAB2	NAB2_3_gene	ZBTB39	0.00418	0.964	0.957	0.987
rs186132169	NGEF	NGEF_3_gene	USP40	-0.0455	0.96	0.953	0.987
rs10933	PBRM1	PBRM1_2_gene	CACNA1D	-0.00376	0.945	0.936	0.987
rs10933	PBRM1	PBRM1_3_gene	CACNA1D	-0.00603	0.976	0.969	0.987
rs10933	PBRM1	PBRM1_3_gene	NEK4	-0.0095	0.954	0.945	0.987
rs10933	PBRM1	PBRM1_3_gene	TKT	0.00295	0.976	0.969	0.987
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHA4	-0.0374	0.974	0.968	0.987
rs4151680	PCDHA123	PCDHA123_2_gene	SRA1	0.00213	0.966	0.959	0.987
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHB5	0.0274	0.954	0.945	0.987
rs4151680	PCDHA123	PCDHA123_3_gene	PCDHGA7	0.00174	0.964	0.956	0.987
rs4151680	PCDHA123	PCDHA123_3_gene	RELL2	-0.00406	0.969	0.962	0.987
rs6071578	PPP1R16B	PPP1R16B_2_gene	RPRD1B	0.0286	0.968	0.959	0.987
rs6071578	PPP1R16B	PPP1R16B_3_gene	SNHG11	-0.00486	0.974	0.968	0.987
rs301791	RERE	RERE_1_gene	PER3	-0.00691	0.972	0.965	0.987
rs301791	RERE	RERE_1_gene	TNFRSF9	0.00612	0.971	0.965	0.987
rs324015	STAT6	STAT6_1_gene	NDUFA4L2	-0.0098	0.975	0.969	0.987
rs324015	STAT6	STAT6_1_gene	SPRYD4	0.00459	0.965	0.958	0.987
rs324015	STAT6	STAT6_2_gene	MARS	0.00438	0.954	0.945	0.987
rs324015	STAT6	STAT6_2_gene	TIMELESS	-0.00287	0.971	0.964	0.987
rs324015	STAT6	STAT6_3_gene	COQ10A	0.00447	0.955	0.945	0.987
rs324015	STAT6	STAT6_3_gene	CTDSP2	-0.00241	0.969	0.961	0.987
rs9882911	TRANK1	TRANK1_1_gene	LRRFIP2	-0.0204	0.958	0.953	0.987
rs2027349	VPS45	VPS45_1_gene	C1orf56	-0.0413	0.973	0.966	0.987
rs2027349	VPS45	VPS45_1_gene	PRPF3	0.00926	0.96	0.952	0.987
rs2027349	VPS45	VPS45_2_gene	ARNT	0.000675	0.973	0.967	0.987
rs2027349	VPS45	VPS45_2_gene	HIST2H2AC	-0.00119	0.951	0.941	0.987
rs2027349	VPS45	VPS45_3_gene	CDC42SE1	-0.00936	0.96	0.95	0.987
rs2027349	VPS45	VPS45_3_gene	OTUD7B	0.0427	0.966	0.958	0.987
rs301791	RERE	RERE_3_gene	CAMTA1	0.00183	0.978	0.972	0.989
rs324015	STAT6	STAT6_2_gene	AGAP2	0.0307	0.978	0.972	0.989
rs12895055	BCL11B	BCL11B_2_gene	CYP46A1	0.0028	0.982	0.978	0.989
rs12716973	KCTD13	KCTD13_2_gene	FBXL19	0.00761	0.983	0.978	0.989
rs12716973	KCTD13	KCTD13_2_gene	ZNF629	0.0348	0.98	0.975	0.989
rs4151680	PCDHA123	PCDHA123_1_gene	PCDHB9	-0.0048	0.982	0.978	0.989
rs6071578	PPP1R16B	PPP1R16B_1_gene	ACTR5	-0.00176	0.982	0.977	0.989
rs11633075	UBE2Q2P1	UBE2Q2P1_2_gene	NMB	0.00774	0.979	0.974	0.989
rs6071578	PPP1R16B	PPP1R16B_1_gene	TTI1	0.00288	0.985	0.981	0.99
rs2027349	VPS45	VPS45_1_gene	MLLT11	-0.00268	0.984	0.98	0.99
rs12716973	KCTD13	KCTD13_1_gene	ZNF629	-0.000757	0.988	0.985	0.993
rs12716973	KCTD13	KCTD13_3_gene	MAZ	-0.000705	0.994	0.992	0.997
rs10933	PBRM1	PBRM1_2_gene	ALAS1	-0.000644	0.994	0.992	0.997
rs4151680	PCDHA123	PCDHA123_2_gene	PCDHA11	0.0203	0.994	0.992	0.997
rs2027349	VPS45	VPS45_2_gene	SV2A	0.00054	0.992	0.99	0.997
rs6071578	PPP1R16B	PPP1R16B_2_gene	FAM83D	-0.00217	0.996	0.994	0.998
rs324017	NAB2	NAB2_3_gene	STAT2	0.0132	0.997	0.996	0.999
rs12716973	KCTD13	KCTD13_3_gene	ZNF747	-0.00617	0.999	0.998	0.999
rs324017	NAB2	NAB2_2_gene	TSPAN31	0.000721	0.998	0.998	0.999
rs7170068	CHRNA3	CHRNA3_2_gene	ADAMTS7	0.00494	1	1	1

cis pairs that passed FDR < 0.1: 4 

cis pairs that have an empirical p values < 0.05: 106